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Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. De plus, nous expédions F-Box Protein 28 Kits (13) et F-Box Protein 28 Protéines (6) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal FBXO28 Primary Antibody pour WB - ABIN1881338
Seki, Ohira, Nagase, Ishikawa, Miyajima, Nakajima, Nomura, Ohara: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. dans DNA research : an international journal for rapid publication of reports on genes and genomes 1998
Show all 5 Pubmed References
It was shown on human primary islets that FBXO28 improves pancreatic beta-cell survival under diabetogenic conditions without affecting insulin secretion.
Expression levels of TP53BP2, FBXO28, and FAM53A genes were associated with patient survival specifically in ER-positive, TP53-mutated tumors.
Fbxo28 regulates topoisomerase IIalpha decatenation activity and plays an important role in maintaining genomic stability.
Refinement of the critical region of 1q41q42 microdeletion syndrome identifies FBXO28 as a candidate causative gene for intellectual disability and seizures.
Study identified F-box protein, FBXO28 that controls MYC-dependent transcription by non-proteolytic ubiquitylation. Depletion of FBXO28 or overexpression of an F-box mutant unable to support MYC ubiquitylation results in an impairment of MYC-driven transcription, transformation and tumourigenesis.
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box protein 28
, F-box only protein 28
, centromere protein 30