anti-F-Box Protein 32 (FBXO32) Anticorps

FBXO32 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. De plus, nous expédions FBXO32 Kits (30) et FBXO32 Protéines (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FBXO32 114907 Q969P5
FBXO32 67731 Q9CPU7
FBXO32 171043 Q91Z62
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Top anti-FBXO32 Anticorps sur

Showing 10 out of 87 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FBXO32 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-FBXO32  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
Souris Chèvre Inconjugué ELISA, WB ABIN570946 (1 µg/mL) staining of Human Skeletal Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 2 to 3 Days
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 2 to 3 Days
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 7 to 9 Days
Boeuf (Vache) Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of Mouse heart lysate, using FBXO32 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277334 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Connectez-vous pour afficher 11 to 12 Days
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat uterus labeled with Anti MAFbx/Fbx32 Polyclonal Antibody, Unconjugated (bs2591R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Connectez-vous pour afficher 3 to 7 Days
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 16 Days

anti-FBXO32 Anticorps mieux référencés

  1. Human Polyclonal FBXO32 Primary Antibody pour ELISA, WB - ABIN451805 : Hanai, Cao, Tanksale, Imamura, Koshimizu, Zhao, Kishi, Yamashita, Phillips, Sukhatme, Lecker: The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. dans The Journal of clinical investigation 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal FBXO32 Primary Antibody pour IF (p), IHC (p) - ABIN747698 : Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats. dans Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2016 (PubMed)

Plus d’anticorps contre FBXO32 partenaires d’interaction

Zebrafish F-Box Protein 32 (FBXO32) interaction partners

  1. Atrogin-1 inactivation leads to progressive impairment of heart and skeletal muscle function and structure. Autophagy is severely impaired in Atrogin-1-deficient zebrafish embryos.

Rainbow Trout (Oncorhynchus mykiss) F-Box Protein 32 (FBXO32) interaction partners

  1. Results suggest that the up-regulation of FBXO32 is associated with skeletal and smooth muscle atrophy that occurs during fasting.

Human F-Box Protein 32 (FBXO32) interaction partners

  1. F-box only protein 32 (FBXO32) directly ubiquitinates C-terminal binding protein 1 (CtBP1), which is required for its stability and nuclear retention.

  2. Authors found that the FBXO32 and SMAD4 levels were higher in normal tissues than in CRC tissues. The expressions of FBXO32 and SMAD4 were related to clinicopathological parameters in CRC.

  3. role of the muscle specific E3s MuRF-1 and MAFbx in skeletal muscle wasting during various pathologies, as well as their regulation by modifiable lifestyle factors, were explored (review)

  4. FBXO32 activates NF-kappaB through IkappaBalpha degradation in inflammatory and genotoxic stress

  5. Transcriptional analysis of endophilin-A mutant mice, complemented by proteomics, highlighted ataxia- and protein-homeostasis-related genes and revealed upregulation of the E3-ubiquitin ligase FBXO32/atrogin-1 and its transcription factor FOXO3A.

  6. Low FBXO32 expression is associated with breast cancer tumorigenesis.

  7. the involvement of oxidative stress in the atrophy of COPD peripheral muscle cells in vitro, via the FoxO1/MuRF1/atrogin-1 signaling pathway of the ubiquitin/proteasome system

  8. These results have revealed the roles for atrogin-1 in the regulation of smooth muscle contractility through enhancement of myocardin ubiquitylation/degradation and its transcriptional activity.

  9. Our results indicate that abnormal SCF activity with subsequent impairment of the autophagic flux due to a novel FBXO32 mutation is implicated in the pathogenesis of Dilated cardiomyopathy .

  10. Our data suggest that FBXO32 is a candidate gene for recessive familial dilated cardiomyopathy. Acting as a cardiac ubiquitin ligase, mutated FBXO32 could perturb the degradation of target proteins in the ubiquitin proteasome system.

  11. Vitamin D3 might have an inhibitory effect on the expression of MAFbx and MuRF1 in skeletal muscle.

  12. Atrogin-1 expression tended to be increased in the skeletal muscle of patients with malignant disease even before cancer related cachexia weight loss.

  13. Expression of USP19 correlates with that of MuRF1 and MAFbx/atrogin-1 in skeletal muscles

  14. FBXO32 targets Lys-326 of c-Myc to form polyubiquitin chains, resulting in inhibition of cell proliferation.

  15. In conclusion, atrogin-1, MuRF1, FOXO1/3A, and eIF3-f mRNA, and protein levels, are differentially regulated by exercise contraction mode but not WPH supplementation combined with hypertrophy-inducing training.

  16. MAFbx not only regulates protein degradation, but also reduces protein synthesis, exerting a dual role in regulating cardiac mass and preventing from cardiac hypertrophy.

  17. FBXO32 methylation status and protein expression were independently associated with survival in ESCC. FBXO32 may be a functional tumor suppressor. Its inactivation through promoter methylation could play an important role in ESCC carcinogenesis.

  18. both MuRF1 and MAFbx are enriched in skeletal, cardiac, and smooth muscle--REVIEW

  19. EZH2 is a key factor in the proliferation and survival of PAX3-FOXO1 alveolar RMS cells working, at least in part, by repressing FBXO32

  20. ATROGIN1 gene expression is increased in patients with severe burn injury.

Pig (Porcine) F-Box Protein 32 (FBXO32) interaction partners

  1. we speculated that the overexpression of FBXO32 is responsible for congenital splay leg syndrome and it plays an important role in the PI3K-Akt pathway

  2. this study shows that aspartate suppresses lipopolysaccharide-induced MAFbx expression in skeletal muscle via activation of Akt signaling, and inhibition of AMPKa and FOXO1 signaling

  3. Porcine congenital splayleg (PCS) is a condition characterized by extensive fibre atrophy and raised fibre density. The combined differential expression of MAFbx and P311 is of potential in the diagnosis of subclinical PCS.

Cow (Bovine) F-Box Protein 32 (FBXO32) interaction partners

  1. A study on the variability of bovine FBXO32 gene that is predictive of genetic potential for body length phenotype.

FBXO32 profil antigène

Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with FBXO32

  • F-box protein 32 (fbxo32) anticorps
  • F-box protein 32 (FBXO32) anticorps
  • F-box protein 32 (Fbxo32) anticorps
  • 4833442G10Rik anticorps
  • AI430017 anticorps
  • Atrogin1 anticorps
  • Fbx32 anticorps
  • Gm20361 anticorps
  • MAFbx anticorps
  • MGC56479 anticorps
  • zgc:56479 anticorps

Protein level used designations for FBXO32

F-box only protein 32 , atrogin-1 , F-box protein 32 , F-box only protein 32-like , atrogin 1 , muscle atrophy F-box protein , atrophy gene 1

393891 Danio rerio
420343 Gallus gallus
464371 Pan troglodytes
475091 Canis lupus familiaris
704804 Macaca mulatta
100026040 Monodelphis domestica
100057506 Equus caballus
100142676 Ovis aries
100356177 Oryctolagus cuniculus
100387690 Callithrix jacchus
100462679 Salmo salar
100499214 Oncorhynchus mykiss
100580109 Nomascus leucogenys
114907 Homo sapiens
733657 Sus scrofa
513776 Bos taurus
67731 Mus musculus
171043 Rattus norvegicus
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