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Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. De plus, nous expédions F-Box Protein 42 Kits (12) et F-Box Protein 42 Protéines (5) et beaucoup plus de produits pour cette protéine.
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SCF (Montrer KITLG Anticorps)(JFK) as a bona fide E3 ligase for ING4 (Montrer ING4 Anticorps) and unraveled the JFK-ING4 (Montrer ING4 Anticorps)-NF-kappaB (Montrer NFKB1 Anticorps) axis as an important player in the development and progression of breast cancer
The findings of this study suggest that a haplotype of the FBXO42 gene might be associated with a higher susceptibility to PD.
Substrate phosphorylation and feedback regulation in JFK-promoted p53 (Montrer TP53 Anticorps) destabilization.
JFK promotes p53 (Montrer TP53 Anticorps) turnover through assembly of an SCF (Montrer KITLG Anticorps) (Skp1 (Montrer SKP1 Anticorps)-Cul1 (Montrer CUL1 Anticorps)-F-box) complex, revealing a pathway for the control of p53 (Montrer TP53 Anticorps) degradation and providing a link between the SCF (Montrer KITLG Anticorps) complex and p53 (Montrer TP53 Anticorps) regulation.
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A\; MIM 601434), cullin (see CUL1\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004
F-box only protein 42
, just one F-box and Kelch domain-containing protein
, F-box protein 42
, F-box only protein 42-like