F-Box Protein 8 Protéines (FBXO8)

FBXO8 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. De plus, nous expédions F-Box Protein 8 Anticorps (55) et F-Box Protein 8 Kits (13) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
FBXO8 26269 Q9NRD0
FBXO8 50753 Q9QZN3
Rat FBXO8 FBXO8 306436  
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Top F-Box Protein 8 Protéines sur anticorps-enligne.fr

Showing 5 out of 7 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Levure Arabidopsis thaliana His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,781.17
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,856.33
Détails

FBXO8 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour F-Box Protein 8 (FBXO8) partenaires d'interaction

Human F-Box Protein 8 (FBXO8) interaction partners

  1. Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC (Montrer FAM126A Protéines)) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC (Montrer FAM126A Protéines). The preferential down-regulation of FBX8 in HCC (Montrer FAM126A Protéines) patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC (Montrer FAM126A Protéines) progression.

  2. FBX8 as a metastasis suppressor that functions through mTOR (Montrer FRAP1 Protéines) signaling pathway and has significant prognostic power.

  3. FBX8 down-expression was an independent prognostic indicator for glioma patient's survival.

  4. FBX8 was markedly down-regulated in gastric cancer tissues. Knocking down FBX8 promoted proliferation and invasion in tumor cell line. Patients with low FBX8 had poor prognosis.

  5. FBX8 is a novel c-Myc binding protein (Montrer PFDN5 Protéines) and that c-Myc (Montrer MYC Protéines) induces cell invasive activity

Mouse (Murine) F-Box Protein 8 (FBXO8) interaction partners

  1. Fbx8, an F-box protein (Montrer FBXO30 Protéines) bearing the Sec7 (Montrer CYTH1 Protéines) domain, mediates ubiquitination of Arf6 (Montrer ARF6 Protéines).

Profil protéine F-Box Protein 8 (FBXO8)

Profil protéine

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Gene names and symbols associated with F-Box Protein 8 Protéines (FBXO8)

  • F-box protein 8 (FBXO8)
  • F-box protein 8 (fbxo8)
  • F-box and associated interaction domains-containing protein (AT2G16810)
  • F-box protein 8 L homeolog (fbxo8.L)
  • F-box protein 8 (Fbxo8)
  • FBS Protéine
  • Fbx8 Protéine
  • FBXO8 Protéine
  • T24I21.22 Protéine
  • T24I21_22 Protéine
  • zgc:136842 Protéine

Protein level used designations for F-Box Protein 8 Protéines (FBXO8)

F-box protein 8 , F-box only protein 8 , F-box only protein 8-like , f-box only protein 8-like , F-box protein Fbx8 , F-box/SEC7 protein FBS

GENE ID SPECIES
461611 Pan troglodytes
699302 Macaca mulatta
100014085 Monodelphis domestica
100061095 Equus caballus
100145349 Xenopus (Silurana) tropicalis
100358150 Oryctolagus cuniculus
100399392 Callithrix jacchus
100442882 Pongo abelii
100516833 Sus scrofa
100549567 Meleagris gallopavo
100566023 Anolis carolinensis
100591261 Nomascus leucogenys
816182 Arabidopsis thaliana
678549 Danio rerio
444719 Xenopus laevis
422565 Gallus gallus
26269 Homo sapiens
477359 Canis lupus familiaris
538528 Bos taurus
50753 Mus musculus
306436 Rattus norvegicus
101119879 Ovis aries
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