FAD-Dependent Oxidoreductase Domain Containing 1 Protéines (FOXRED1)

FOXRED1 encodes a protein that contains a FAD-dependent oxidoreductase domain. De plus, nous expédions FAD-Dependent Oxidoreductase Domain Containing 1 Anticorps (45) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
FOXRED1 55572 Q96CU9
FOXRED1 235169 Q3TQB2
Rat FOXRED1 FOXRED1 315547  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
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Wheat germ Humain GST tag 2 μg Connectez-vous pour afficher 11 to 12 Days
$338.33
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FOXRED1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1) partenaires d'interaction

Human FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1) interaction partners

  1. Results show that depletion of FOXRED1 in myoblasts results in decreased levels of fully assembled complexes I and II. FOXRED1 associates with the ND1 (Montrer MT-ND1 Protéines)-containing subcomplexes of ~370 kDa and ~620 kDa and that FOXRED1 activity is required for the formation of a 550-kDa subcomplex of complex I.

  2. Loss of FOXRED1, coupled with protein, choline and/or folate-deficient diets results in the depletion of glutathione, the dysregulation of nitric oxide metabolism and the peroxynitrite-mediated inactivation of complex I.

  3. A structural model of FOXRED1 reveals a large substrate-binding cavity and a putative oxygen-binding site.

  4. FOXRED1 is a crucial component in the productive assembly of respiratory chain complex I and that mutations in FOXRED1 leading to partial loss of function cause defects in complex I biogenesis.

  5. Mutations in FOXRED1 are associated with complex I deficiency.

Profil protéine FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1)

Profil protéine

This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with FOXRED1

  • FAD dependent oxidoreductase domain containing 1 (FOXRED1)
  • FAD-dependent oxidoreductase domain containing 1 (FOXRED1)
  • FAD-dependent oxidoreductase domain containing 1 (Foxred1)
  • BC024806 Protéine
  • H17 Protéine
  • RGD1311785 Protéine
  • TEG-23 Protéine
  • Tex23 Protéine

Protein level used designations for FOXRED1

FAD-dependent oxidoreductase domain-containing protein 1 , testis expressed gene 23

GENE ID SPECIES
55572 Homo sapiens
489292 Canis lupus familiaris
510097 Bos taurus
235169 Mus musculus
315547 Rattus norvegicus
100513997 Sus scrofa
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