anti-FIP1 Like 1 (S. Cerevisiae) Anticorps
FIP1L1 encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors.
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anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) (full length) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) (C-Term) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) (AA 1-378) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) (AA 509-558) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) (N-Term) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps (Biotin) Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps (Alexa Fluor 350) Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps (Alexa Fluor 488) Primary Antibody
anti-FIP1 Like 1 (S. Cerevisiae) (FIP1L1) anticorps (Alexa Fluor 555) Primary Antibody
FIP1 Like 1 (S. Cerevisiae) (FIP1L1) profil antigène
Profil protéine
This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity. Its N-terminus contains a PAP-binding site and its C-terminus an RNA-binding domain. An interstitial chromosomal deletion on 4q12 creates an in-frame fusion of human genes FIP1L1 and PDGFRA (platelet-derived growth factor receptor, alpha). The FIP1L1-PDGFRA fusion gene encodes a constitutively activated tyrosine kinase that joins the first 233 amino acids of FIP1L1 to the last 523 amino acids of PDGFRA. This gene fusion and chromosomal deletion is the cause of some forms of idiopathic hypereosinophilic syndrome (HES). This syndrome, recently reclassified as chronic eosinophilic leukemia (CEL), is responsive to treatment with tyrosine kinase inhibitors. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene names and symbols associated with FIP1L1
- factor interacting with PAPOLA and CPSF1 (fip1l1) anticorps
- factor interacting with PAPOLA and CPSF1 (FIP1L1) anticorps
- factor interacting with PAPOLA and CPSF1 S homeolog (fip1l1.S) anticorps
- factor interacting with PAPOLA and CPSF1 (Fip1l1) anticorps
- FIP1 like 1 (S. cerevisiae) (Fip1l1) anticorps
- FIP1 like 1b (S. cerevisiae) (fip1l1b) anticorps
- 1300019H17Rik anticorps
- FIP1 anticorps
- fip1l1 anticorps
- hFip1 anticorps
- Rhe anticorps
- Rje anticorps
- wu:fd36f11 anticorps
- zgc:103421 anticorps
Protein level used designations for FIP1L1
FIP1 like 1 , FIP1-like 1 protein , pre-mRNA 3'-end-processing factor FIP1 , FIP1L1 cleavage and polyadenylation specific factor subunit , factor interacting with PAP , rearranged in hypereosinophilia
GENE ID | SPECIES |
---|---|
733481 | Xenopus (Silurana) tropicalis |
100172699 | Pongo abelii |
81608 | Homo sapiens |
494780 | Xenopus laevis |
289582 | Rattus norvegicus |
422754 | Gallus gallus |
612980 | Canis lupus familiaris |
100138550 | Bos taurus |
66899 | Mus musculus |
450021 | Danio rerio |
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