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When transfected into cell lines in which it is not expressed, suppresses cell growth. De plus, nous expédions FAM107A Anticorps (24) et FAM107A Kits (13) et beaucoup plus de produits pour cette protéine.
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This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 (Montrer COMMD1 Protéines) that is involved in NF-kappaB (Montrer NFKB1 Protéines) degradation and cell cycle suppression in neuroblastoma (Montrer ARHGEF16 Protéines) cells.
Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression.
Results found that DRR expression leads to elevated AKT (Montrer AKT1 Protéines) activation by recruiting AKT (Montrer AKT1 Protéines) to focal adhesios in a manner dependent on SRC (Montrer SRC Protéines)-family kinases (SFKs) and cell adhesion.
DRR1 protein is expressed in normal cells, particularly in the nervous system during embryogenesis, is involved in neuronal cell survival, and is downregulated during neuroblastoma (Montrer ARHGEF16 Protéines) carcinogenesis.
Expression of the down-regulated in renal cell carcinoma (Montrer MOK Protéines) gene (DRR1) gene at 3p14.2 was lost in 7 and down regulated in 2 "chr3+" tumours.
TU3A is epigenetically inactivated in human cancer
Endogenous DRR1 localizes to some, but not all, synapses, with preference for the presynaptic region. Enhancement of DRR1 expression reduced spine density, diminished the probability of synaptic glutamate (Montrer GRIN1 Protéines) release, and altered cognitive performance.
When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development.
uncharacterized protein LOC494764
, down-regulated in renal cell carcinoma 1
, family with sequence similarity 107 member A transcript
, protein FAM107A
, downregulated in renal cell carcinoma