anti-Family with Sequence Similarity 20, Member C (FAM20C) Anticorps

FAM20C encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. De plus, nous expédions FAM20C Protéines (3) et FAM20C Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FAM20C 56975 Q8IXL6
FAM20C 80752 Q5MJS3
FAM20C 304334  
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Top anti-FAM20C Anticorps sur anticorps-enligne.fr

Showing 10 out of 47 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FAM20C Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FAM20C Antibody Titration:  0.2-1 ug/ml  Positive Control:  NTERA2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué IHC (p), WB DMP4 antibody (C-term) (ABIN654936) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: FAM20C Antibody [NBP2-16415] - Immunohistochemical analysis of paraffin-embedded MDA-MB468 xenograft, using antibody at 1:100 dilution. Western Blot: FAM20C Antibody [NBP2-16415] - Sample (30 ug of whole cell lysate) A: Molt-4 7. 5% SDS PAGE gel, diluted at 1:500. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$559.35
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin fixed and paraffin embedded human breast carcinoma  reacted WITH DMP4 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of DMP4 Antibody (C-term) in HepG2 cell line lysates (35ug/lane).This demonstrates the DMP4 antibody detected the DMP4 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB FAM20C antibody used at 1 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 9 to 11 Days
$473.93
Détails
Humain Lapin Inconjugué WB FAM20C antibody used at 1 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 9 to 11 Days
$473.93
Détails

Plus d’anticorps contre FAM20C partenaires d’interaction

Human Family with Sequence Similarity 20, Member C (FAM20C) interaction partners

  1. that FAM20C may affect the biomineralization by the means more than local phosphorylation of extracellular matrix proteins and systemic phosphorus homeostasis

  2. Histidine-rich Ca-binding protein (HRC) was phosphorylated by family with sequence similarity 20C (Fam20C) both in vitro and in vivo.

  3. These results suggest that TET1 potentially promotes the cytodifferentiation potential of human dental pulp cells through its DNA demethylation machinery and upregulation of FAM20C protein expression.

  4. findings clarify FAM20C's role in hard tissue formation and mineralization, and show that Raine syndrome is congenital sclerosing osteomalacia with cerebral calcification.

  5. Alterations of Fam20C activity, promoted by myriocin and sphingolipids, are not accompanied by any significant change in Fam20C protein. These data provide the proof of concept that Fam20C activity is under the control of sphingolipid signaling

  6. Our report reinforces that Raine syndrome is compatible with life, and that mild hypophosphatemia and amelogenesis imperfecta are key features of the attenuated form.

  7. Fam20A potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro.

  8. The Fam20C-and VLK-family of kinases mediate the phosphorylation of proteins in the secretory pathway and extracellular space.Mutation in several secretory pathway kinases cause human disease

  9. by treating Fam20C expressing HEK293T cells with myriocin, a potent inhibitor of the sphingosine biosynthetic pathway, the activity of Fam20C released into the conditioned medium is substantially decreased corroborating the concept that sphingosine

  10. Using CRISPR/Cas9 genome editing, mass spectrometry, and biochemistry, study identifies more than 100 secreted phosphoproteins as genuine Fam20C substrates; further, study shows that Fam20C exhibits broader substrate specificity than previously appreciated.

  11. phenotype in two families with non-lethal Raine syndrome with FAM20C mutations

  12. Findings suggest that certain homozygous FAM20C mutations can cause FGF23-related hypophosphatemic osteomalacia and indicate the multiple roles of FAM20C in bone.

  13. Results suggest that FAM20C suppresses FGF23 production by enhancing DMP1 expression, and inactivating mutations in FAM20C cause FGF23-related hypophosphatemia by decreasing transcription of DMP1.

  14. We report on a child who is homozygous for a 487-kb deletion in 7p22.3 that contains FAM20C

  15. Fam20C phosphorylates FGF23, which promotes FGF23 proteolysis by furin by blocking O-glycosylation by polypeptide N-acetylgalactosaminyltransferase 3.

  16. mutations in FAM20C provide a putative new mechanism in human subjects leading to dysregulated FGF23 levels, hypophosphatemia, hyperphosphaturia, dental anomalies, intracerebral calcifications and osteosclerosis of the long bones

  17. Our results identify FAM20C as a kinase for secreted phosphoproteins and establish a biochemical basis for Raine syndrome.

  18. Fam20C appears to be the Golgi casein kinase that phosphorylates secretory pathway proteins within S-x-E motifs; Fam20C phosphorylates caseins and several secreted proteins implicated in biomineralization; mutations in Fam20C cause an osteosclerotic bone dysplasia known as Raine syndrome

  19. Osteosclerotic bone dysplasia in siblings with a Fam20C mutation

  20. This study defines the causative role of FAM20C in this lethal osteosclerotic disorder and its crucial role in normal bone development.

Mouse (Murine) Family with Sequence Similarity 20, Member C (FAM20C) interaction partners

  1. that Fam20c indeed regulates cell behaviors and cell signaling pathway in a cell-autonomous manner

  2. family with sequence similarity member 20C is the primary, but not the only, kinase for the SIBLINGs

  3. Fam20A potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro.

  4. Loss of Fam20C function leads to periodontal disease in mice

  5. Successful generation of Fam20C-GFP transgenic mice will provide a unique model for studying Fam20C gene expression and the biological function of this gene during odontogenesis and osteogenesis

  6. we have successfully generated the immortalized mouse floxed Fam20c dental papilla mesenchymal and osteoblast cell lines.

  7. These results indicated that the downregulation of Dmp1 may not directly associate with, or significantly contribute to the bone and dentin defects in the Fam20C-cKO mice.

  8. that FAM20C is not a constituent of the enamel extracellular matrix and functions intracellularly within ameloblasts.

  9. FAM20C is a molecule essential to amelogenesis, its inactivation in the dental epithelium does not significantly affect dentinogenesis.

  10. FAM20C is essential to the differentiation and mineralization of dental tissues through the regulation of molecules critical to the differentiation of tooth-formative cells.

  11. Our findings indicate that FAM20C is essential to the differentiation of osteoblasts/osteocytes and is involved in the regulation of phosphate homeostasis via the mediation of FGF23

  12. Fam20c null mice develop hypophosphatemic rickets and defective enamel and dentin

  13. temporospatial expression profile of FAM20C

  14. This study defines the causative role of FAM20C in this lethal osteosclerotic disorder and its crucial role in normal bone development.

FAM20C profil antigène

Profil protéine

This gene encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. A similar gene in mice encodes a protein that plays a role in dentin mineralization, and mutations in the human gene are associated with the autosomal recessive disorder Raine syndrome.

Gene names and symbols associated with FAM20C

  • FAM20C, golgi associated secretory pathway kinase (FAM20C) anticorps
  • family with sequence similarity 20, member C (FAM20C) anticorps
  • family with sequence similarity 20, member C (Fam20c) anticorps
  • FAM20C, golgi associated secretory pathway kinase (Fam20c) anticorps
  • family with sequence similarity 20, member Cb (fam20cb) anticorps
  • C76981 anticorps
  • DMP-4 anticorps
  • DMP4 anticorps
  • GEF-CK anticorps
  • mKIAA4081 anticorps
  • RGD1311980 anticorps
  • RNS anticorps
  • si:ch73-266a4.1 anticorps

Protein level used designations for FAM20C

family with sequence similarity 20, member C , dentin matrix protein 4 , extracellular serine/threonine protein kinase FAM20C , golgi-enriched fraction casein kinase , fam20c2

GENE ID SPECIES
100231802 Taeniopygia guttata
100342945 Oryctolagus cuniculus
416445 Gallus gallus
56975 Homo sapiens
491596 Canis lupus familiaris
80752 Mus musculus
304334 Rattus norvegicus
560397 Danio rerio
534672 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-FAM20C (FAM20C) Anticorps
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