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Required for proper chromosome congression and alignment during mitosis. De plus, nous expédions FAM83D Protéines (3) et beaucoup plus de produits pour cette protéine.
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FAM83D promotes HCC (Montrer FAM126A Anticorps) recurrence by promoting CD44 (Montrer CD44 Anticorps) expression and CD44 (Montrer CD44 Anticorps)+ CSCs malignancy.
FAM83D knockdown up-regulated the protein expression level of F-box and WD repeat domain-containing 7 (FBXW7 (Montrer FBXW7 Anticorps)), but diminished the Notch1 (Montrer NOTCH1 Anticorps) protein expression level.
Higher level of FAM83D expression is positively correlated with an increase in genome instability in many cancer.
upregulation of FAM83D, a potential oncotarget gene, may be triggered by epigenetic events and can contribute to hepatocarcinogenesis
NMR-derived secondary chemical shifts and relaxation properties show that the Chica LC8 (Montrer DYNLL1 Anticorps) binding domain is essentially disordered with a dynamically restricted segment in one linker between motifs.
Taken together, these results demonstrate that FAM83D is a novel oncogene (Montrer RAB1A Anticorps) in HCC (Montrer FAM126A Anticorps) development and may constitute a potential therapeutic target in HCC (Montrer FAM126A Anticorps).
Results demonstrate that FAM83D has prognostic value for breast cancer patients and is a novel oncogene (Montrer RAB1A Anticorps) in breast cancer development that at least in part acts through mTOR (Montrer FRAP1 Anticorps) hyper-activation by inhibiting FBXW7 (Montrer FBXW7 Anticorps).
interaction partner of the chromokinesin Kid that is required for the generation of polar ejection forces and chromosome congression
Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to the spindle microtubules (By similarity).
, spindle protein CHICA
, Protein FAM83D-A
, Protein FAM83D-B