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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). De plus, nous expédions FANCI Protéines (3) et FANCI Kits (2) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal FANCI Primary Antibody pour WB - ABIN152583
Yuan, El Hokayem, Zhou, Zhang: FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures. dans The Journal of biological chemistry 2009
Show all 2 Pubmed References
Human Polyclonal FANCI Primary Antibody pour IP, WB - ABIN253065
Colnaghi, Jones, Cotto-Rios, Schindler, Hanenberg, Huang: Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair. dans Blood 2011
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.
Fanconi anemia group I protein
, Fanconi anemia group I protein homolog