Fas Apoptotic Inhibitory Molecule (FAIM) Kits ELISA

The protein encoded by FAIM protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. De plus, nous expédions FAIM Anticorps (119) et FAIM Protéines (9) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
FAIM 55179 Q9NVQ4
Anti-Rat FAIM FAIM 140930 Q8R5H8
Anti-Souris FAIM FAIM 23873 Q9WUD8
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Détails

Plus Kits ELISA pour FAIM partenaires d'interaction

Human Fas Apoptotic Inhibitory Molecule (FAIM) interaction partners

  1. the anti-apoptotic effect of SRT1720 was mitigated by FAIM knockdown with a small interfering RNA-targeted FAIM. These results indicated that pretreatment with SRT1720 improves survival of aged hMSCs, and enhances their therapeutic efficacy for rat myocardial infarction (MI).

  2. subcellular fractionation experiments revealed that, in contrast to FAIM-S and FAIM-L, FAIM-S_2a and FAIM-L_2a are able to localize to the nucleus, where they may have additional functions. In summary, here we report on two novel FAIM isoforms that may have relevant roles in the physiology and pathology of the nervous system

  3. Data indicate that FAIM is a novel regulator of insulin signalling and plays an essential role in energy homoeostasis.

  4. FAIM modulates IGF-1-induced Akt activation and IRF4 expression and has a role in multiple myeloma cell survival

  5. FAIM (1-90) was crystallized and diffracted to a resolution of 2.5 A; the crystal belonged to space group P3(1), with unit-cell parameters a=b=58.02, c=71.11 A, alpha=beta=90, gamma=120 degrees.

  6. Human keratinocytes were transfected with either Flip, Faim, or Lifeguard (LFG). Our results suggest that heterotopic expression of antiapoptotic proteins can induce the resistance of keratinocytes to a major mechanism of rejection.

  7. Expression of the long form of Fas apoptotic inhibitory molecule (FAIML) results in the protection of neurons from the cytotoxic actions of death ligands.

  8. FAIM acts to specifically enhance CD40 signaling for NF-kappaB activation, IRF-4 expression, and BCL-6 down-regulation in vitro, but has no effect on its own

Mouse (Murine) Fas Apoptotic Inhibitory Molecule (FAIM) interaction partners

  1. The neuron-specific form of FAIM protein (FAIM-L) is a death receptor antagonist that stabilizes XIAP protein levels, thus preventing death receptor-induced neuronal apoptosis. Here we show that FAIM-L modulates synaptic transmission, prevents chemical-LTD induction in hippocampal neurons, and thwarts axon degeneration after nerve growth factor (NGF) withdrawal.

  2. Data indicate that FAIM is a novel regulator of insulin signalling and plays an essential role in energy homoeostasis.

  3. defined a TCR-induced FAIM/Akt/Nur77 signaling axis that is critical for modulating the apoptosis of developing thymocytes

  4. The NMR solution structure of the C-terminal domain of murine FAIM is solved in isolation and revealed to be a novel protein fold, a noninterleaved seven-stranded beta-sandwich.

  5. FAIM plays a novel role in modulating Fas-mediated apoptosis and acts through influencing the expression of c-FLIP and regulating the physical binding of caspase-8 to Fas.

  6. FAIM is expressed in germinal center B cells, enhances interferon regulatory factor (IRF)4 expression, and is in turn positively regulated through IRF4 in a positive reinforcing (i.e., feed-forward) system.

FAIM profil antigène

Antigen Summary

The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with FAIM

  • Fas apoptotic inhibitory molecule (FAIM) anticorps
  • Fas apoptotic inhibitory molecule (Faim) anticorps
  • Fas apoptotic inhibitory molecule (faim) anticorps
  • Fas apoptotic inhibitory molecule L homeolog (faim.L) anticorps
  • Fas apoptotic inhibitory molecule (Tsp_00038) anticorps
  • Fas apoptotic inhibitory molecule b (faimb) anticorps
  • faim anticorps
  • FAIM1 anticorps
  • zgc:92712 anticorps

Protein level used designations for FAIM

fas apoptotic inhibitory molecule 1 , Fas apoptotic inhibitory molecule , Fas apoptosis inhibitory molecule 1 , uncharacterized protein LOC436668

GENE ID SPECIES
55179 Homo sapiens
460729 Pan troglodytes
716216 Macaca mulatta
140930 Rattus norvegicus
616795 Bos taurus
496608 Xenopus (Silurana) tropicalis
485687 Canis lupus familiaris
424270 Gallus gallus
23873 Mus musculus
734582 Xenopus laevis
10901294 Trichinella spiralis
100568454 Sus scrofa
100727709 Cavia porcellus
436668 Danio rerio
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