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FCGR2C encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. De plus, nous expédions FCGR2C Anticorps (53) et FCGR2C Protéines (2) et beaucoup plus de produits pour cette protéine.
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When higher-affinity genotypes for FCGR2A (Montrer FCGR2A Kits ELISA), FCGR3A (Montrer CD16 Kits ELISA), and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2 (Montrer IL2 Kits ELISA)... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 (Montrer IL2 Kits ELISA) treatment
Gene copy number variation (CNV) of the PKLR (Montrer PKLR Kits ELISA), FCGR2A (Montrer FCGR2A Kits ELISA), FCGR2C, and FCGR3 (Montrer CD16 Kits ELISA) genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.
FCGR2A (Montrer FCGR2A Kits ELISA) and FCGR2C polymorphisms may also contribute to immunocomplexemia present in sarcoidosis.
FCGR2C SNPs that associated with vaccine efficacy in RV144 also strongly associated with the expression of FCGR2A/C and one of them also associated with the expression of Fc receptor-like A (FCRLA), another Fc-gamma receptor (FcgammaR) gene
These include an FCGR2A (Montrer FCGR2A Kits ELISA)/2C chimeric gene that causes a decreased expression
Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A (Montrer CD16 Kits ELISA) were less frequent than for FCGR3B (Montrer CD16 Kits ELISA) and FCGR2C.
Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus.(28-40) Status: Complete Incomplete Delete
Only FCGR3A, FCGR2C and FCGR3B show copy number variation, in contrast to FCGR2A and FCGR2B.
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.
Fc gamma receptor IIC
, IgG Fc receptor II-c
, immunoglobulin G Fc receptor II-c
, low affinity immunoglobulin gamma Fc region receptor II-c