anti-Fibroblast Growth Factor Receptor Anticorps
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
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anti-Fibroblast Growth Factor Receptor (FGFR) anticorps Primary Antibody
anti-Fibroblast Growth Factor Receptor (FGFR) anticorps Primary Antibody
Fibroblast Growth Factor Receptor (FGFR) profil antigène
Profil protéine
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
Gene names and symbols associated with FGFR
- heartless (htl) anticorps
- fibroblast growth factor receptor 1 L homeolog (fgfr1.L) anticorps
- fibroblast growth factor receptor (FGFR) anticorps
- fibroblast growth factor receptor 1 S homeolog (fgfr1.S) anticorps
- fibroblast growth factor receptor (fgfr) anticorps
- fibroblast growth factor receptor 1 (FGFR1) anticorps
- fibroblast growth factor receptor 1 (fgfr1) anticorps
- fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L) anticorps
- basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849) anticorps
- ach anticorps
- bfgfr anticorps
- cd331 anticorps
- cd333 anticorps
- cek anticorps
- cek2 anticorps
- CG7223 anticorps
- CT22273 anticorps
- CT39172 anticorps
- DFGF-R1 anticorps
- DFGF-R2 anticorps
- Dfr-1 anticorps
- Dfr1 anticorps
- DFR1/DFGF-R2 anticorps
- Dmel\\CG7223 anticorps
- DmHD-38 anticorps
- DPR3 anticorps
- dtk1 anticorps
- DTRK(FR1) anticorps
- EMS2 anticorps
- FGF-R2 anticorps
- fgfbr anticorps
- fgfr anticorps
- fgfr-1 anticorps
- fgfr-3 anticorps
- fgfr1 anticorps
- FGFR2 anticorps
- flg anticorps
- FLG-1 anticorps
- flt-2 anticorps
- flt2 anticorps
- Fr1 anticorps
- hbgfr anticorps
- HD-38 anticorps
- hsfgfr3ex anticorps
- Htl anticorps
- HTL/FGFR1 anticorps
- i79 anticorps
- i100 anticorps
- i150 anticorps
- j372 anticorps
- jtk4 anticorps
- kal2 anticorps
- n-sam anticorps
- ogd anticorps
- Tk1 anticorps
- X1FGFR anticorps
- XFGFR-1 anticorps
- xfgfr1 anticorps
- XFGFRA2 anticorps
Protein level used designations for FGFR
CG7223-PA , CG7223-PB , CG7223-PC , FGF receptor , fibroblast growth factor receptor , fibroblast growth factor receptor 1 , htl-PA , htl-PB , htl-PC , FGFR-1 , fibroblast growth factor receptor-1 , fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , basic fibroblast growth factor receptor 1 , basic fibroblast growth factor receptor 1-like
| GENE ID | SPECIES |
|---|---|
| 42160 | Drosophila melanogaster |
| 399444 | Xenopus laevis |
| 373310 | Strongylocentrotus purpuratus |
| 394418 | Xenopus laevis |
| 445706 | Ciona intestinalis |
| 475582 | Canis lupus familiaris |
| 548648 | Xenopus (Silurana) tropicalis |
| 779370 | Xenopus laevis |
| 6037802 | Culex quinquefasciatus |
| 100390192 | Callithrix jacchus |
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- anti-Fibronectin Leucine Rich Transmembrane Protein 1 Anticorps
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- anti-Fibronectin Type III and SPRY Domain Containing 1 Anticorps
- anti-Fibronectin Type III Domain Containing 3A Anticorps
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