anti-Fibulin 5 (FBLN5) Anticorps

The protein encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. De plus, nous expédions Fibulin 5 Kits (41) et Fibulin 5 Protéines (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FBLN5 10516 Q9UBX5
FBLN5 23876 Q9WVH9
FBLN5 29158 Q9WVH8
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Top anti-Fibulin 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 147 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, WB ABIN185699 (0.1µg/ml) staining of Human Ovary lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Humain Souris Inconjugué ELISA, IHC, WB Figure 1: Western blot analysis using FBLN5 mouse mAb against truncated FBLN5-His recombinant protein. Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 mouse mAb. Dilution: 1/200 - 1/1000 100 μL Connectez-vous pour afficher 10 to 11 Days
$577.50
Détails
Boeuf (Vache) Lapin Inconjugué WB   200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using FBLN5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded Human pancreas carcinoma (left) and breast carcinoma (right) tissue, showing membrane and cytoplasmic (pancreas carcinoma) localization, membrane (breast carcinoma) localization using EphB4 mouse mAb with DAB staining. Dilution: 1:200~~1000 100 μL Connectez-vous pour afficher 10 to 11 Days
$456.07
Détails
Humain Souris Inconjugué ELISA, IHC, WB Figure 1: Western blot analysis using Fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2). Dilution: 1/500 - 1/2000 Figure 2: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using fibulin5 mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL Connectez-vous pour afficher 10 to 11 Days
$577.50
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Human Lung Tissue. 100 μg Connectez-vous pour afficher 13 to 16 Days
$350.00
Détails
Humain Lapin Inconjugué ELISA, WB Western Blot (WB) analysis of specific cells using Fibulin-5 Polyclonal Antibody. 100 μL Connectez-vous pour afficher Disponible
$363.46
Détails
Humain Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Western blot analysis of extracts from 3T3 cells, using FBLN5 antibody. ABIN6275124 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails

anti-Fibulin 5 Anticorps mieux référencés

  1. Human Monoclonal Fibulin 5 Primary Antibody pour IHC, ELISA - ABIN969144 : Wen, Hochholdinger, Sauer, Bruce, Schnable: The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis. dans Plant physiology 2005 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Fibulin 5 Primary Antibody pour ELISA, WB - ABIN969145 : Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis. dans The British journal of dermatology 2005 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal Fibulin 5 Primary Antibody pour IHC, ELISA - ABIN969131 : Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. dans American journal of human genetics 2003 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal Fibulin 5 Primary Antibody pour IHC, ELISA - ABIN966143 : Lee, Roy, Mogford, Schiemann, Mustoe: Fibulin-5 promotes wound healing in vivo. dans Journal of the American College of Surgeons 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal Fibulin 5 Primary Antibody pour IHC (fro), IHC (p) - ABIN537123 : Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection. dans Surgery 2005 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal Fibulin 5 Primary Antibody pour IHC - ABIN966131 : Nakamura, Ruiz-Lozano, Lindner, Yabe, Taniwaki, Furukawa, Kobuke, Tashiro, Lu, Andon, Schaub, Matsumori, Sasayama, Chien, Honjo: DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 3 Pubmed References

  7. Dog (Canine) Polyclonal Fibulin 5 Primary Antibody pour ELISA, WB - ABIN547744 : Albig, Neil, Schiemann: Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. dans Cancer research 2006 (PubMed)

Plus d’anticorps contre Fibulin 5 partenaires d’interaction

Human Fibulin 5 (FBLN5) interaction partners

  1. study reports the first Chinese family with c.1117C>T mutation of FBLN5; findings confirm a novel subtype of autosomal-dominant Charcot-Marie-Tooth disease due to a mutation in the FBLN5 gene

  2. The results showed a significant upregulation of ECM1 and ITGB3, and a significant downregulation for FBLN5 in pelvic organ prolapse patients.

  3. Serum fibulin-5 concentration can be regarded as a biomarker for evaluating disease severity and predicting prognosis in intracerebral hemorrhage patients.

  4. Fibulin-5 expression is increased in the induced sputum of asthmatic patients.

  5. Data show that fibulin-5 strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1/TIE-2 receptor axis.

  6. FBLN5 downregulation in human abdominal aortic aneurysm could contribute to extracellular matrix remodeling induced by the inflammatory component of the disease.

  7. Identify a SOX9/HDAC-dependent mechanism involved in the down-regulation of FBLN5 by inflammation in abdominal aortic aneurysms.

  8. We also found that Fibulin-5 reduces the level of expression of Ki-67, a nuclear protein associated with cell proliferation. Moreover, reduction in Fibulin-5 expression corresponds to an increase of Ki-67 detection in breast tissue samples

  9. study demonstrates the pivotal role of the extracellular protein, fibulin-5, on the adhesion and proliferation of human keloid-derived cells, through binding to integrin beta-1

  10. Lower FBLN-5 expression is an important indicator of poor survival in hepatocellular carcinoma. FBLN-5 inhibits HCC adhesion/motility via integrin-dependent mechanism.

  11. FBLN5 mRNA expression is upregulated in response to cAMP-mediated decidualization of primary human endometrial stromal cells, although FBLN5 itself does not enhance decidualization

  12. Fibulin-5 is significantly down-regulated in ovarian carcinoma and acts as a tumour suppressor by inhibiting the migration and invasion of ovarian cancer cells.

  13. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM interactions to reduce ROS production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  14. Data suggest that fibulin-5 functions as a metastasis suppressor in lung cancer by modulating tumor microenvironment to suppress Wnt/beta-catenin signaling.

  15. Fibulin-5 may be implicated in the aetiology of rectal prolapse in a subgroup of young male patients.

  16. Fibulin-5 expression is a disease marker of hepatic fibrosis.

  17. Loss of FBLN5 expression is associated with glioma.

  18. Up-regulation of elastin and fibulin-5 mRNA levels in ICA were strongly correlated with family history of cardiovascular disease when compared to CCA

  19. Data suggest that expression of FBLN5 (fibulin 5) and LOXL1 (lysyl oxidase-like protein 1) (but not expression of elastin) is down-regulated in uterosacral ligaments of postmenopausal women with pelvic organ prolapse.

  20. These results indicate that Fibulin-5 inhibits hepatocellular carcinoma invasion and metastasis by suppressing matrix metalloproteinase-7 expression.

Mouse (Murine) Fibulin 5 (FBLN5) interaction partners

  1. Fibulin 5 localized to the RPE, choroid, and Bruch's membrane. Knockout mice had a significantly reduced scotopic A response by 1 month of age, when compared to their wild-type counterparts, which remained throughout life and only declined as a result of normal aging. The functional decline was associated with reduced number of photoreceptor cells.

  2. Fibulin-5 overexpression promoted the proliferation and migration of airway smooth muscle cell.

  3. Fibulin-5 overexpression significantly down-regulated the phosphorylation level of eIF2alpha and subsequently inhibited the TRPV1 channel and CREB/CGRP signaling

  4. therapy-induced hypoxia elevated Fbln5 expression, whereas pharmacologic inhibition of TGF-beta signaling reduced Fbln5 expression. These findings offer insight into the signaling axis that induces Fbln5 expression in PDA and a potential strategy to block its production

  5. Identify a SOX9/HDAC-dependent mechanism involved in the down-regulation of FBLN5 by inflammation in abdominal aortic aneurysms.

  6. involved in the stiffening of fibrotic tissue

  7. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM interactions to reduce ROS production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  8. While premaxillo-maxillary suture mesenchymal cells in fibulin-5-null mice were capable of differentiating into osteoblasts, suture cells in mutant mice were less proliferative.

  9. Fibulin-5 plays critical roles in proliferation, migration and invasion of certain tumors, and the effect of fibulin-5 on tumorigenesis appears to be largely context-dependent. (Review)

  10. These results are consistent with a role for TGFbeta2 in lung septation and for Ltbp4 in regulating fibulin-5 dependent elastic fiber assembly.

  11. Without LTBP-4, fibulin-5 and tropoelastin deposition was discontinuous and punctate in vitro and in vivo

  12. This study used the maturation of fibulin-5 knockout (KO) and wild-type mice to study the effects of fragmented elastic fibers on the growth and remodeling of carotid arteries.

  13. suggest that uPA promotes cell migration by binding to fibulin-5, initiating its cleavage by plasmin, which leads to its dissociation from beta1-integrin and thereby unblocks the capacity of integrin to facilitate cell motility

  14. MMP9 and fibulin-5 have roles in progression of pelvic organ prolapse in mice and humans

  15. mechanical testing and confocal imaging of common carotid arteries from fibulin-5 null mice and littermate controls to characterize the mechanical behavior and microstructural content of these arteries

  16. These findings introduce a novel function for Fbln5 in the regulation of integrin-induced reactive oxygen species production.

  17. Fibulin-2 and fibulin-5 cooperatively function to form the internal elastic lamina during postnatal development by directing the assembly of elastic fibers, and are responsible for maintenance of the adult vessel wall after injury

  18. Fibulin-5 is a calcium-dependent, elastin-binding protein that localizes to the surface of elastic fibres in vivo.

  19. FBLN-5 is a novel TGF-beta-inducible target gene that regulates cell growth and motility in a context-specific manner and affects protein kinase activation by TGF-beta.

  20. coordinately expressed and regulated with elastin in lung fibroblasts and may serve a key role during lung injury and repair.

Cow (Bovine) Fibulin 5 (FBLN5) interaction partners

  1. These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 regulates targeting of DANCE on suitable microfibrils to form elastic fibers.

Fibulin 5 (FBLN5) profil antigène

Profil protéine

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Gene names and symbols associated with anti-Fibulin 5 (FBLN5) Anticorps

  • fibulin 5 (fbln5) anticorps
  • fibulin 5 (FBLN5) anticorps
  • fibulin 5 (Fbln5) anticorps
  • A55 anticorps
  • ADCL2 anticorps
  • ARCL1A anticorps
  • ARMD3 anticorps
  • DANCE anticorps
  • DKFZp469K0327 anticorps
  • EVEC anticorps
  • FBLN5 anticorps
  • FIBL-5 anticorps
  • Fibulin-5 anticorps
  • MGC108414 anticorps
  • UP50 anticorps
  • zgc:103575 anticorps

Protein level used designations for anti-Fibulin 5 (FBLN5) Anticorps

fibulin-5 , fibulin 5 , fibulin-5-like , developmental arteries and neural crest EGF-like protein , urine p50 protein , FIBL-5 , EVEC , dance , embryonic vascular EGF repeat-containing protein

GENE ID SPECIES
449806 Danio rerio
453112 Pan troglodytes
595007 Xenopus (Silurana) tropicalis
697372 Macaca mulatta
100172278 Pongo abelii
100222931 Taeniopygia guttata
100392828 Callithrix jacchus
100480209 Ailuropoda melanoleuca
100588580 Nomascus leucogenys
10516 Homo sapiens
480227 Canis lupus familiaris
23876 Mus musculus
29158 Rattus norvegicus
535185 Bos taurus
100347343 Oryctolagus cuniculus
100715192 Cavia porcellus
100155248 Sus scrofa
423413 Gallus gallus
101112927 Ovis aries
100063331 Equus caballus
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