anti-Forkhead Box N1 (FOXN1) Anticorps

The protein encoded by FOXN1 is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. De plus, nous expédions FOXN1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FOXN1 8456 O15353
FOXN1 15218 Q61575
FOXN1 287469  
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Top anti-FOXN1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 94 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, IHC ABIN185069 (20µg/ml) staining of paraffin embedded Human Thymus Medulla. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN185069 (4µg/ml) staining of paraffin embedded Human Thymus. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. 100 μg 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-FOXN1 Antibody Titration: 5.0ug/ml ELISA Titer: 1:1562500 Positive Control: Raji cell lysate FOXN1 is supported by BioGPS gene expression data to be expressed in Raji 100 μL 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of FOXN1 expression in Raji (A), HeLa (B), A549 (C), NIH3T3 (D), PC12 (E) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon labeled with Anti-FOXN1 Polyclonal Antibody, Unconjugated (ABIN1387592) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse spleen labeled with Anti-FOXN1 Polyclonal Antibody, Unconjugated (ABIN1387592) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$329.45
Détails
Humain Lapin Inconjugué EIA, FACS, WB Flow cytometric analysis of A549 cells using FOXN1 Antibody (Center) Cat.-No AP51716PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of FOXN1 Antibody (Center) in A549,NCI-H460 cell line lysates (35ug/lane). This demonstrates the FOXN1 antibody detected the FOXN1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Détails
Cheval Chèvre Inconjugué ELISA, IHC, IHC (p) Human Thymus, Medulla (formalin-fixed, paraffin-embedded) stained with FOXN1 antibody ABIN297057 at 20 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-FOXN1 antibody IHC of human thymus, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué WB WB Image FOXN1 antibody [C3], C-term detects FOXN1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FOXN1 antibody [C3], C-term , diluted at 1:500. WB Image FOXN1 antibody [C3], C-term detects FOXN1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with FOXN1 antibody [C3], C-term , diluted at 1:500. 100 μL 3 to 4 Days
$466.18
Détails
Chien Lapin Inconjugué WB 100 μL 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-FOXN1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μL 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis FOXN1 using Jurkat whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails

anti-FOXN1 Anticorps mieux référencés

  1. Human Polyclonal FOXN1 Primary Antibody pour IHC (p), ELISA - ABIN547137 : Schlake, Schorpp, Maul-Pavicic, Malashenko, Boehm: Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype. dans Developmental dynamics : an official publication of the American Association of Anatomists 2000 (PubMed)

  2. Human Polyclonal FOXN1 Primary Antibody pour IF (p), IHC (p) - ABIN1387592 : Volpi, Yamazaki, Brauer, van Rooijen, Hayashida, Slavotinek, Sun Kuehn, Di Rocco, Rivolta, Bortolomai, Du, Felgentreff, Ott de Bruin, Hayashida, Freedman, Marcovecchio, Capuder, Rath, Luche, Hagedorn et al.: EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. ... dans The Journal of experimental medicine 2017 (PubMed)

Plus d’anticorps contre FOXN1 partenaires d’interaction

Zebrafish Forkhead Box N1 (FOXN1) interaction partners

  1. the foxn1-mcm2 axis plays a central role in the genetic regulatory network controlling thymus development in zebrafish

  2. zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment

  3. an evolutionarily conserved role of BMP signaling in the maintenance of Foxn1 expression.

Human Forkhead Box N1 (FOXN1) interaction partners

  1. Here, by engineering a time-delayed feedback system of BMP inhibition in mouse embryos, the authors demonstrate that thymopoiesis irreversibly fails if Foxn1 gene expression does not occur during a defining time span in mid-gestation. They also reveal an epistatic interaction between the extent of BMP signalling and the gene dosage of Foxn1.

  2. FOXN1 founder Italian mutation identified in an indian newborn with severe combined immunodeficiency.

  3. Whole-exome sequencing in a South American cohort links ALDH1A3, FOXN1 and RARB/retinoic acid regulation pathways to autism spectrum disorders.

  4. Identification of a unique mutation in FOXN1 that led to severe combined immunodeficiency in a female infant is reported.

  5. These results show that miR-18b and miR-518b are upstream controllers of FOXN1-directed epithelial lineage development.

  6. The retinoid-related orphan receptor RORalpha promotes keratinocyte differentiation via FOXN1.

  7. This is the first description of leucoderma occurring in a patient with Foxn1 deficiency, as well as the first report of this pigment abnormality following thymus transplantation.

  8. results show that FOXN1 is crucial for in utero T cell development, but not for B and NK cell differentiation

  9. role of FOXN1 in immunological disorders characterized by abnormal T-cell development or abnormal T-cell regulatory homeostasis [Review]

  10. study uncovered a positive regulatory loop between FGFR3 and FOXN1 that underlies a benign versus malignant skin tumor phenotype

  11. Mutation of the FOXN1 gene is associated with congenital severe combined immunodeficiency associated with alopecia

  12. These results establish a role for FOXN1 in initiation of terminal differentiation and implicate Akt in subsequent events.

  13. Mechanisms and signaling pathways by which Foxn1 modulates keratinocyte differentiation in hair follicle and nail apparatus. Molecular and functional consequences of loss of function of Foxn1 protein in skin. Review.

  14. Foxn1 is a sensitive and specific marker for thymoma and thymic carcinoma.

  15. Foxn1/FGF2 pathway involved in instructing melanocytes where to place pigment.

Mouse (Murine) Forkhead Box N1 (FOXN1) interaction partners

  1. Thymopoesis is largely normal in Foxn1+/nu mice.

  2. Study report the identification of a highly conserved Foxn1-binding sequence that is located proximal to the beta5t-coding sequence in the mouse genome. This cis-regulatory element is indeed essential for the optimal expression of beta5t in cortical thymic epithelial cells and the optimal production of CD8+ T cells.

  3. data identify the transcription factor Foxn1 as a potential key epidermal regulator modifying both epidermal and dermal healing processes after cutaneous wounding

  4. MicroRNA-205 maintains T cell development following stress by regulating Foxn1 and its two regulated targets, stem cell factor and ccl25, following stress.

  5. this study identified Bmp4 as a significant factor for improved maintenance of Foxn1 expression, promotion of thymic epithelial progenitor populations self-renewal and immature epithelial cell differentiation and survival

  6. results show that Foxn1, and alleles under its control, are expressed in the pre-meiotic male germline, revealing a new tool for germline targeting of genes, and raising important concerns for gender selection when using Foxn1 regulatory elements.

  7. this study shows that critical events in thymic lympho-stromal cross-talk and T cell selection are regulated by Foxn1

  8. sphingolipids and fatty acids associated with a decrease in glycerolipids suggest that the lipidome in mice skin is regulated by the Foxn1 gene

  9. Foxn1 transcription factor regulates wound healing of skin through promoting epithelial-mesenchymal transition.

  10. early differentiation and maturation of cortical and medullary thymic epithelial cells coincides with precise sub-lineage-specific regulation of Foxn1 expression levels.

  11. upregulated expression in thymus epithelial cells upon challenges

  12. Chromatin immunoprecipitation assay using RarB as the immunoprecipitation target suggests retinoic acid regulation of Aldh1a3 and Foxn1 in mice.

  13. The maturation and distribution of thymic epithelial cells in the Foxn1(-/-) thymic rudiment and the thymopoiesis of this newly developed rudiment, were examined.

  14. Expression of FoxN1 in early life adversely influence immature epithelial cells T and B cell, and skin epithelial development.

  15. this study presents the characterization of the adult thymic epithelial stem cells and demonstrates the dispensability of FoxN1 function for their stemness.

  16. Enforced Foxn1 expression is sufficient to reprogramme fibroblasts into functional thymic epithelial cells.

  17. TAp63 levels are positively correlated with TEC senescence but inversely correlated with expression of FoxN1 and FoxN1-regulated thymic epithelial cell differentiation.

  18. Upregulation of a single transcription factor can substantially reverse age-related thymic involution, identifying FOXN1 as a specific target for improving thymus function.

  19. The similar characteristics between IL-22 and Foxn1 leads to a speculation that Foxn1 is probably involved in thymic regeneration driven by IL-22.

  20. skews multipotent progenitors development toward T lineage

FOXN1 profil antigène

Profil protéine

The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene names and symbols associated with anti-Forkhead Box N1 (FOXN1) Anticorps

  • forkhead box N1 (FOXN1) anticorps
  • forkhead box N1 (foxn1) anticorps
  • forkhead box N1 (foxN1) anticorps
  • forkhead box protein N1 (LOC100125524) anticorps
  • forkhead box N1 (Foxn1) anticorps
  • D11Bhm185e anticorps
  • Fkh19 anticorps
  • FKHL20 anticorps
  • foxN anticorps
  • foxn1 anticorps
  • HFH-11 anticorps
  • Hfh11 anticorps
  • nu anticorps
  • nude anticorps
  • Rnu anticorps
  • RONU anticorps
  • Whn anticorps
  • whnb anticorps

Protein level used designations for anti-Forkhead Box N1 (FOXN1) Anticorps

forkhead box protein N1 , forkhead box N1 , forkhead box N protein , forkhead box protein N1-like , transcription factor Forkhead box protein N1 , Rowett nude , winged helix nude , winged-helix nude , winged-helix transcription factor nude , HNF-3/forkhead homolog 11 , hepatocyte nuclear factor 3 forkhead homolog 11

GENE ID SPECIES
417570 Gallus gallus
100059109 Equus caballus
266748 Danio rerio
468381 Pan troglodytes
708926 Macaca mulatta
100024620 Monodelphis domestica
100303472 Saccoglossus kowalevskii
100410086 Callithrix jacchus
100467385 Ailuropoda melanoleuca
100601006 Nomascus leucogenys
100125524 Oryzias latipes
8456 Homo sapiens
491168 Canis lupus familiaris
516724 Bos taurus
15218 Mus musculus
287469 Rattus norvegicus
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