anti-Formin Homology 2 Domain Containing 1 (FHOD1) Anticorps

Human Formin Homology 2 Domain Containing 1 (FHOD1) interaction partners

1. results suggest that FHOD1 participates in key cellular processes that are dysregulated in malignancy

2. FHOD1 and INF2 (Montrer INF2 Anticorps) are novel regulators of inter- and intra-structural contractility of podosomes.

3. Immunostaining of sections of hearts with both anti-FHOD1 antibodies confirmed the presence of FHOD1 in intercalated discs and double immunostaining demonstrated its colocalisation with cadherin, plakoglobin (Montrer JUP Anticorps) and shifted localization to connexin43 (Montrer GJA1 Anticorps).

4. FHOD1 promotes formation of short actin filaments and transiently associates with transverse arcs providing tight temporal and spatial control of the formation and turnover of transverse arcs into mature ventral stress fibers during dynamic cell behavior.

5. the diaphanous formin (Montrer FMN1 Anticorps) FHOD1 as an interaction partner of N2G

6. FHOD1 participates in cytoskeletal changes in epithelial-mesenchymal transition.

7. Cdh1 (Montrer CDH1 Anticorps) contributes to spatiotemporal organization of AurB (Montrer AURKB Anticorps) activity, and organization of FHOD1 activity by AurB (Montrer AURKB Anticorps) contributes to daughter cell spreading after mitosis.

8. FHOD1 stabilizes actin filaments by protecting barbed ends from depolymerization with its dimeric FH2 domain, whereas the region N-terminal to the FH1 domain mediates F-actin bundling by simultaneously binding to the sides of adjacent F-actin filaments.

9. SIRPalpha/CD172a (Montrer SIRPA Anticorps) and FHOD1 are unique markers of littoral cells, a recently evolved major cell population of red pulp of human spleen.

10. FHOD1 and PPM1F (Montrer PPM1F Anticorps) (direct regulators of the actin cytoskeleton) were identified as novel targets of miR (Montrer MLXIP Anticorps)-200c. Expression levels of FHOD1 and PPM1F (Montrer PPM1F Anticorps) were inversely correlated with miR (Montrer MLXIP Anticorps)-200c level in breast cancer cell lines and breast cancer patient samples.

Mouse (Murine) Formin Homology 2 Domain Containing 1 (FHOD1) interaction partners

1. FHOD1 is regulated by ROCK for cytoplasm actin assembly and spindle migration during mouse oocyte meiosis.

2. We report here that a major formin in mouse fibroblasts, FHOD1, is recruited to integrin clusters, resulting in actin assembly.

3. Letter: G-protein coupled and ITAM receptor regulation of the formin (Montrer FMN1 Anticorps) FHOD1 through Rho kinase (Montrer ROCK2 Anticorps) in platelets.