anti-Formin-Like 2 (FMNL2) Anticorps

FMNL2 encodes a formin-related protein. De plus, nous expédions FMNL2 Protéines (4) et FMNL2 Kits (2) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FMNL2 71409 A2APV2
FMNL2 114793 Q96PY5
FMNL2 311033  
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Top anti-FMNL2 Anticorps sur

Showing 10 out of 28 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Cobaye Lapin Inconjugué WB WB Suggested Anti-FMNL2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué WB 100 μL 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with FMNL2 antibody ABIN297065 at 5-10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-FMNL2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
Chimpanzé Lapin Inconjugué IHC (p), WB 50 μg 6 to 8 Days
Humain Souris Inconjugué ELISA, WB FMNL2 monoclonal antibody (M01), clone 2B4 Western Blot analysis of FMNL2 expression in IMR-32 . Western Blot detection against Immunogen (45.32 KDa) . 100 μg 11 to 12 Days
Humain Lapin Inconjugué IHC (p), WB 50 μg 12 to 14 Days
Humain Lapin Inconjugué IF, IHC (p) Immunofluorescent staining of U-251 MG with FMNL2 polyclonal antibody  (Green) shows positivity in plasma membrane and cytoplasm. Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human duodenum with FMNL2 polyclonal antibody  shows strong cytoplasmic positivity in glandular cells. 100 μL 11 to 12 Days
Chimpanzé Lapin Inconjugué IHC, WB 0.05 mg 2 to 3 Days
Humain Lapin Inconjugué WB 100 μg 2 to 3 Days

anti-FMNL2 Anticorps mieux référencés

  1. Human Monoclonal FMNL2 Primary Antibody pour ELISA, WB - ABIN566725 : Zhu, Liang, Ding: Overexpression of FMNL2 is closely related to metastasis of colorectal cancer. dans International journal of colorectal disease 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal FMNL2 Primary Antibody pour ICC, IF - ABIN4312213 : Gardberg, Talvinen, Kaipio, Iljin, Kampf, Uhlen, Carpén: Characterization of Diaphanous-related formin FMNL2 in human tissues. dans BMC cell biology 2010 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre FMNL2 partenaires d’interaction

Mouse (Murine) Formin-Like 2 (FMNL2) interaction partners

  1. Our data thus link FMNL2/3 formins to actin assembly-dependent functions of Cdc42 in anterograde transport through the Golgi apparatus.

  2. force generation in lamellipodia strongly depends on FMNL formin activity.

  3. FMNL1 and FMNL2 are required non-redundantly in the repair of damaged myofibrils.

  4. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  5. mDia1-FH2 has an effect on the conformation of actin filaments

Human Formin-Like 2 (FMNL2) interaction partners

  1. The outcome of this study illustrated that LINC00483 promoted colorectal cancer cells proliferation and metastasis via modulating FMNL2 by acting as a competitive RNA of miR-204-3p.

  2. Findings reveal that the aberrant activation of FMNL2 promotes the pathogenesis of adenomyosis through inducing the EMT process.

  3. Data indicate that the interaction of cortactin and formin-like 2 (FMNL2) could promote the invadopodia formation and matrix degradation.

  4. FMNL2 knockout cells were characterized by impaired filopodia formation similar to depletion of the Rho GTPase Cdc42.

  5. Data demonstrate that the FMNL2/COMMD10/p65 NF kappaB axis acts as a critical regulator in the maintenance of metastatic phenotypes in colorectal cancer.

  6. Our data proved that RMRP acted as an oncogene LncRNA to promote the expression of KRAS, FMNL2 and SOX9 by inhibiting miR-206 expression in lung cancer. These data suggested that RMRP might serve as a therapeutic target in lung adenocarcinoma

  7. FMNL2 is likely to be generally required in melanoma cells for invasion.

  8. miR-206 functioned as a tumor suppressor in the progression of colorectal cancer(CRC) by targeting FMNL2 and c-MET. Restoration of miR-206 expression may represent a promising therapeutic approach for targeting malignant CRC.

  9. Capping protein and FMNL2 functionally coregulate filament barbed-end assembly.

  10. The two interacting FMNL-Cdc42 heterodimers expose six membrane interaction motifs on a convex protein surface, the assembly of which may facilitate actin filament elongation at the leading edge of lamellipodia and filopodia.

  11. These data establish a role for FMNL2 in the regulation of beta1-integrin and provide a mechanistic understanding of the function of FMNL2 in cancer invasiveness.

  12. MiR-34a was down-regulated in colorectal cancer cells and inversely correlated with FMNL2 and E2F5 expressions. Our study suggests that miR-34a is an important tumor suppressor of CRC progression by targeting FMNL2 and E2F5.

  13. Rac1-induced actin assembly and subsequent AJ formation critically depends on FMNL2.

  14. miR-137, induced by its upstream transcription factor HMGA1, can suppress colorectal cancer cell invasion and metastasis by targeting FMNL2.

  15. Protein N-myristoylation plays critical roles in the cellular morphological changes induced by FMNL2 and FMNL3.

  16. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  17. formin-like 2 expression correlated positively with tumor differentiation (P = .046) and vascular invasion (P = .008). Patients whose tumors had lower formin-like 2 expression had shorter overall survival times

  18. Findings identify a novel EMT and tumor promoting function for FMNL2, which is involved in TGF-beta-induced EMT and colorectal carcinoma cell invasion via Smad3 effectors, or in collaboration with MAPK/MEK pathway.

  19. a novel regulatory and functional interaction between RhoC and FMNL2 for modulating cell shape and invasiveness and provide mechanistic insight into RhoC-specific signalling events.

  20. FMNL2 may play an important role in the metastasis of CRC and may be a useful marker for metastasis of CRC.

FMNL2 profil antigène

Profil protéine

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.

Gene names and symbols associated with anti-Formin-Like 2 (FMNL2) Anticorps

  • formin-like 2 (Fmnl2) anticorps
  • formin like 2 (FMNL2) anticorps
  • formin-like protein 2 (LOC476151) anticorps
  • formin-like 2a (fmnl2a) anticorps
  • formin like 2 (Fmnl2) anticorps
  • 5430425K04Rik anticorps
  • FHOD2 anticorps
  • fmnl2 anticorps
  • Man anticorps
  • si:ch211-279a7.1 anticorps

Protein level used designations for anti-Formin-Like 2 (FMNL2) Anticorps

formin-like domain containing protein MAN , formin-like protein 2 , protein Man , formin homology 2 domain containing 2 , formin homology 2 domain-containing protein 2 , formin-like 2

71409 Mus musculus
114793 Homo sapiens
459663 Pan troglodytes
476151 Canis lupus familiaris
695391 Macaca mulatta
771739 Gallus gallus
100006456 Danio rerio
100543936 Meleagris gallopavo
311033 Rattus norvegicus
788312 Bos taurus
100723045 Cavia porcellus
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