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FPR1 encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. De plus, nous expédions FPR1 Kits (8) et FPR1 Protéines (5) et beaucoup plus de produits pour cette protéine.
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Human Monoclonal FPR1 Primary Antibody pour CyTOF, FACS - ABIN4899071
Prevete, Liotti, Visciano, Marone, Melillo, de Paulis: The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. dans Oncogene 2015
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Human Monoclonal FPR1 Primary Antibody pour FACS - ABIN4895417
Schneider, Weaver, Gaur, Tripathi, Jesaitis, Zelenka, Gao, Murphy: The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. dans The Journal of biological chemistry 2012
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Human Polyclonal FPR1 Primary Antibody pour IHC, IHC (p) - ABIN4312515
Gardner, Yazid, Ribeiro, Ali, Dick: Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice. dans Translational vision science & technology 1970
Taken together, our results suggest that intracellular FPR in naive CD4 (Montrer CD4 Anticorps) T cells and surface FPRs in activated CD4 (Montrer CD4 Anticorps) T cells might regulate immune responses by regulating CD4 (Montrer CD4 Anticorps) T cell activity.
the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS (Montrer IRF6 Anticorps)-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases
The data demonstrate that FPR1 is involved in neuroblastoma (Montrer ARHGEF16 Anticorps) development and could represent a therapy option for the treatment of neuroblastoma (Montrer ARHGEF16 Anticorps).
FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2 (Montrer FPR2 Anticorps).
Formylated MHC class Ib (Montrer HLAF Anticorps) binding peptides activate both human and mouse neutrophils primarily through FPR1.
The inhibitory function of oxidant sensing by TRPM2 (Montrer CLU Anticorps) requires the oxidation of Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 internalization and signaling inhibition
FPR1 expression is significantly upregulated in human masticatory mucosa during wound healing
FAM19A4 (Montrer FAM19A4 Anticorps) is a novel ligand of formyl peptide receptor 1.
The authors describe here the activation of isolated human blood neutrophils by TcdB and, moreover, by toxin fragments generated by limited proteolytical digestion via the FPR1 receptor.
these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.
FPR1-deficient mice showed a slight but significant decrease of demyelination in the corpus callosum and reduced glial cell activation.
the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS (Montrer TLR4 Anticorps)-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases
Intravital TPLSM revealed that formyl-peptide-FPR1 signaling is responsible for regulating neutrophil chemotaxis to allow migration into the necrotic area in hepatic ischemia-reperfusion injury
Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.
Blocking of FPR1 completely abrogated the fMet-Leu-Phe-, gliadin- and synthetic peptide-induced migration.
Ovalbumininduced airway inflammation is mediated by upregulation of the TLR2/MyD88 (Montrer MYD88 Anticorps)/NFkappaB signaling pathway and inhibition of LXA4R.
Deficiency of formyl peptide receptor 1 is associated with increased inflammation and enhanced liver injury after LPS (Montrer TLR4 Anticorps)-stimulation
Fpr1/2 are critical for normal healing of the sterile skin wound by mediating the first wave of neutrophil infiltration.
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.
N-formylpeptide chemoattractant receptor
, fMLP receptor
, fMet-Leu-Phe receptor
, N-formyl peptide receptor
, lipoxin A4 receptor