Four and A Half LIM Domains 1 (FHL1) Kits ELISA

FHL1 encodes a member of the four-and-a-half-LIM-only protein family.

list all ELISA KIts Gène GeneID UniProt
Anti-Humain FHL1 FHL1 2273 Q13642
Anti-Souris FHL1 FHL1 14199 P97447
Anti-Rat FHL1 FHL1 25177 Q9WUH4
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Top Four and A Half LIM Domains 1 Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$736.84
Détails
Rat
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$875.60
Détails
Souris
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$875.60
Détails

Plus Kits ELISA pour Four and A Half LIM Domains 1 partenaires d'interaction

Human Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. Altogether, the specific localization of FHL1B and its modulation in disease-patient's myoblasts confirmed FHL1-related Emery-Dreifuss muscular dystrophy as a nuclear envelope disease.

  2. Low FHL1 expression is associated with head and neck squamous cell carcinoma.

  3. We have uncovered FHL1 as a novel potential regulator of calcium homeostasis in both fish and humans and have implicated it in isolated hypoparathyroidism.

  4. Mutations in FHL1 cause unclassifiable cardiomyopathy with coexisting Emery-Dreifuss muscular dystrophy.

  5. results provide evidence that FHL1A interacts with PLEKHG2 and regulates cell morphological change through the activity of PLEKHG2.

  6. a novel FHL1 splice site variant results in the absence of FHL1A and the abundance of FHL1C, which may contribute to the complex and severe phenotype of Uruguay syndrome.

  7. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E (Montrer CCNE1 Kits ELISA) were markedly elevated at both the protein and mRNA level.

  8. results indicate that anti-FHL1 autoantibodies in peripheral blood have promising potential as a biomarker to identify a subset of severe IIM.

  9. In healthy individuals, FHL1A is the predominant splice variant and is mainly found in skeletal and cardiac muscle. In two individuals with an Emery-Dreifuss plus phenotype with pulmonary artery hypoplasia and facial dysmorphology, there was demonstrated loss of isoform A and B, and an almost 200-fold overexpression of isoform C.

  10. FRG1 mice overexpressing FHL1 showed an improvement in the dystrophic phenotype

Mouse (Murine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. KyoT2 downregulates airway remodeling and resistance in asthmatic mice through a Hes1 (Montrer HES1 Kits ELISA)-dependent mechanism.

  2. Results found that osteogenesis increases with the overexpression of Fhl1 and decreases with reduced Fhl1 expression and suggest that Fhl1 mediates interacting estrogen and Wnt (Montrer WNT2 Kits ELISA) signaling during osteogenesis.

  3. Findings indicate that loss of function is responsible for the myopathy in the Fhl1 W122S knock-in mice.

  4. The CSL-KyoT2 corepressor complex is a negative regulator of Notch (Montrer NOTCH1 Kits ELISA) signaling.

  5. Data show that loss of FHL1 function leads to myopathy in vivo and suggest that loss of function of FHL1 may be one of the mechanisms underlying muscle dystrophy in patients with FHL1 mutations.

  6. Fhl1 transcriptional changes provide salutary effects on stressed myocytes in cardiomyopathy.

  7. Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2 (Montrer FHL2 Kits ELISA)) bind to and regulate activity of Prkd1 (protein kinase D (Montrer PRKD1 Kits ELISA) 1) in cardiac/ventricular myocytes; knockdown of Fhl1 down-regulates Prkd1 (Montrer PRKD1 Kits ELISA) activation.

  8. A novel mechanism involving four-and-a-half LIM domain protein (Montrer PDLIM7 Kits ELISA)-1 and extracellular signal-regulated kinase-2 (Montrer MAPK1 Kits ELISA) regulates titin (Montrer TTN Kits ELISA) phosphorylation and mechanics.

  9. Wnt (Montrer WNT2 Kits ELISA) signaling induces muscle cell differentiation, at least partly, through Fhl1 activation.

  10. FHL1 is a novel regulator of myosin-binding (Montrer PPP1R12A Kits ELISA) protein C (Montrer PROC Kits ELISA) activity that may have a role in sarcomere assembly

Pig (Porcine) Four and A Half LIM Domains 1 (FHL1) interaction partners

  1. The LIM domain protein (Montrer PDLIM7 Kits ELISA) FHL1C interacts with tight junction protein ZO-1 (Montrer TJP1 Kits ELISA) contributing to the epithelial-mesenchymal transition of a breast adenocarcinoma cell line.

Four and A Half LIM Domains 1 (FHL1) profil antigène

Antigen Summary

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

Gene names and symbols associated with FHL1

  • four and a half LIM domains 1 (fhl1) anticorps
  • four and a half LIM domains 1 (FHL1) anticorps
  • four and a half LIM domains 1a (fhl1a) anticorps
  • Four and a half LIM domains protein 1 (fhl1) anticorps
  • four and a half LIM domains 1 S homeolog (fhl1.S) anticorps
  • four and a half LIM domains 1 (Fhl1) anticorps
  • DKFZp468O1927 anticorps
  • fhl anticorps
  • FHL-1 anticorps
  • Fhl1 anticorps
  • FHL1A anticorps
  • FHL1B anticorps
  • fhla anticorps
  • FLH1A anticorps
  • KyoT anticorps
  • MGC89165 anticorps
  • SLIM anticorps
  • SLIM-1 anticorps
  • SLIM1 anticorps
  • SLIMMER anticorps
  • XMPMA anticorps
  • zgc:92025 anticorps

Protein level used designations for FHL1

four and a half LIM domains 1 , four and a half LIM domains protein 1-like , four and a half LIM domains a , four and a half LIM domains protein 1 , Four and a half LIM domains protein 1 , four and a half lim domains protein 1 , LIM protein SLIMMER , four-and-a-half Lin11, Isl-1 and Mec-3 domains 1 , skeletal muscle LIM-protein 1 , FHL-1 , RAM14-1 , RBP-associated molecule 14-1 , SLIM , SLIM-1 , four and a half LIM domains 1 protein

GENE ID SPECIES
448334 Xenopus (Silurana) tropicalis
710692 Macaca mulatta
100172515 Pongo abelii
100307044 Ovis aries
100357263 Oryctolagus cuniculus
100387250 Callithrix jacchus
100590327 Nomascus leucogenys
399646 Danio rerio
100196873 Salmo salar
100529032 Ictalurus punctatus
447182 Xenopus laevis
2273 Homo sapiens
14199 Mus musculus
25177 Rattus norvegicus
509056 Bos taurus
397667 Sus scrofa
492162 Canis lupus familiaris
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