FREM2 encodes a membrane protein that belongs to the FRAS1 family.
FREM2 profil antigène
This gene encodes a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes. Mutations in this gene are associated with Fraser syndrome.
Gene names and symbols associated with FREM2
FRAS1 related extracellular matrix protein 2 (FREM2) anticorps
Fras1 related extracellular matrix protein 2 (Frem2) anticorps
Protein level used designations for FREM2
, FRAS1-related extracellular matrix protein 2
, NV domain containing protein NV1
, NV domain-containing protein 1