G Protein-Coupled Receptor 35 (GPR35) Kits ELISA

Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. De plus, nous expédions GPR35 Anticorps (65) et GPR35 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
GPR35 2859 Q9HC97
Anti-Souris GPR35 GPR35 64095 Q9ES90
Anti-Rat GPR35 GPR35 367315  
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Top GPR35 Kits ELISA sur anticorps-enligne.fr

Showing 2 out of 6 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.056 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
Humain < 0.056 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days

Plus Kits ELISA pour GPR35 partenaires d'interaction

Human G Protein-Coupled Receptor 35 (GPR35) interaction partners

  1. high level expression of G protein-coupled receptor 35 V2/3 mRNA in regional lymph nodes of colon cancer patients is a sign of poor prognosis.

  2. The histology of colon sections from GPR35(-/-) mice with dextran sulfate sodium-induced colitis showed extensive pathological changes including submucosal edema, diffuse ulcerations, and evidence of complete loss of crypts compared to wild-type mice with DSS-induced colitis.

  3. Immunoreactivity for GPR35 was detected in normal corneas, keratoconus and Fuchs' dystrophy, mainly in the corneal epithelium and endothelium. In corneas with Fuchs' dystrophy, less intensive immunoreactivity for GPR35 in endothelium was revealed.

  4. We performed a label-free kinome short hairpin RNA screen and identified a putative signaling network of GPR35 in HT-29 cells, some of which was validated using gene expression, biochemical and cellular assays. The results showed that GPR35 induced hypoxia-inducible factor 1alpha, and was involved in synaptic transmission, sensory perception, the immune system, and morphogenetic processes.

  5. Using exome array data, we identified GPR35 as a novel susceptibility gene associated with chronic AIC in pediatric cancer patients

  6. GPR35 interacts with CXCL17 in breast cancer cells.

  7. Small molecules that stimulate or block GPR35 activity can modulate vascular proliferation and migration.

  8. This article shows that GPR35 is the receptor of CXCL17.

  9. Single-nucleotide polymorphism in GPR35 gene is associated with Crohn's disease.

  10. results clearly show that R4.60, R(164), R(167), and R6.58 play crucial roles in the agonist initiated activation of GPR35.

  11. GPR35 shows associations in both ulcerative colitis (UC) and primary sclerosing cholangitis (PSC), whereas TCF4 represents a PSC risk locus not associated with UC. Both loci may represent previously unexplored aspects of PSC pathogenesis.

  12. This review presents a summary of what is known about the G-protein coupled receptors GPR35 and GPR55 and their potential characterization as lysophospholipid or cannabinoid receptors, respectively--{REVIEW}

  13. screening assays used to identification of small MW agonists; some compounds are species-specific agonists; agonists/ligands include zaprinast, cromolyn & dicumarol

  14. human iNKT cells express GPR35 functionally active in reducing IL-4 release.

  15. These results strongly suggest that 2-acyl lysophosphatidic acid is an endogenous ligand for GPR35.

  16. The results of the study demonstrate the coupling of GPR35 to endogenous G proteins that modulate neuronal Ca2+ channel and thereby provide evidence for a potential role of GPR35 in regulating neuronal excitability and synaptic transmission

Mouse (Murine) G Protein-Coupled Receptor 35 (GPR35) interaction partners

  1. Kynurenic acid increases energy utilization by activating G protein-coupled receptor Gpr35, which stimulates lipid metabolism, thermogenic, and anti-inflammatory gene expression in adipose tissue.

  2. GPR35 signaling promotes mucosal repair by inducing fibronectin and integrin alpha5 expression, coupling to Gi protein, and activating ERK1/2 in colonic epithelial cells. These findings define GPR35 as a candidate therapeutic target in inflammatory bowel disease.

  3. Cardiac expression of GPR35 is regulated by hypoxia through activation of HIF-1.

  4. GPR35 activation may contribute to KYNA effects on the previously reported decrease of brain extracellular glutamate levels and reduction of excitatory transmission

GPR35 profil antigène

Antigen Summary

Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.

Gene names and symbols associated with GPR35

  • G protein-coupled receptor 35 (GPR35) anticorps
  • G-protein coupled receptor 35 (LOC486201) anticorps
  • G protein-coupled receptor 35 (Gpr35) anticorps
  • GPR35 anticorps
  • KPG_007 anticorps

Protein level used designations for GPR35

G protein-coupled receptor 35 , G-protein coupled receptor 35 , KYNA receptor , kynurenic acid receptor

424833 Gallus gallus
460070 Pan troglodytes
486201 Canis lupus familiaris
505056 Bos taurus
2859 Homo sapiens
64095 Mus musculus
367315 Rattus norvegicus
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