anti-G Protein-Coupled Receptor 68 (GPR68) Anticorps

Proton-sensing receptor involved in pH homeostasis. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GPR68 8111 Q15743
GPR68 238377 Q8BFQ3
GPR68 314386  
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Top anti-GPR68 Anticorps sur anticorps-enligne.fr

Showing 10 out of 78 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-GPR68 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué ICC, IF, IHC, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué IC, IF, WB Western blot analysis of GPR68 expression in HeLa (A), mouse spleen (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Anti-GPR68 antibody  ABIN1048865 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, ICC, IHC, IHC (p) Anti-GPR68 antibody  ABIN1048864 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR68 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, IHC (p) Anti-GPR68 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p) Anti-GPR68 antibody  ABIN1048861 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR68 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué ELISA, IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with GPR68 antibody ABIN213457 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-GPR68 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with GPR68 antibody ABIN213456 at 10-20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-GPR68 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails

anti-GPR68 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal GPR68 Primary Antibody pour WB - ABIN1881516 : Singh, Berk, Oates, Zhao, Tan, Jiang, Zhou, Kirmani, Steinmetz, Lindner, Xu: Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. dans Journal of the National Cancer Institute 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal GPR68 Primary Antibody pour IHC (p) - ABIN2475955 : Mogi, Tomura, Tobo, Wang, Damirin, Kon, Komachi, Hashimoto, Sato, Okajima: Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation. dans Journal of pharmacological sciences 2005 (PubMed)

  3. Cow (Bovine) Polyclonal GPR68 Primary Antibody pour ICC, IF - ABIN1048863 : Komarova, Pereverzev, Shum, Sims, Dixon: Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. dans Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre GPR68 partenaires d’interaction

Human G Protein-Coupled Receptor 68 (GPR68) interaction partners

  1. Our results suggest that OGR1-dependent increases in TRPC4 (Montrer TRPC4 Anticorps) expression may favour formation of highly Ca(2 (Montrer CA2 Anticorps)+) -permeable TRPC4 (Montrer TRPC4 Anticorps)-containing channels that promote transformed granule cell migration. Increased motility of cancer cells is a prerequisite for cancer invasion and metastasis, and our findings may point towards a key role for TRPC4 (Montrer TRPC4 Anticorps) in progression of certain types of medullablastoma.

  2. Blocking of GPR68 or NF-small ka, CyrillicB activity severely attenuated acidification induced IL-8 (Montrer IL8 Anticorps) production.

  3. These results suggest that zOGR1, but not GPR4 (Montrer GPR4 Anticorps), is also a metal-sensing G-protein-coupled receptor (Montrer ADRA1A Anticorps) in addition to a proton-sensing G-protein-coupled receptor (Montrer ADRA1A Anticorps), although not all metals that activate hOGR1 activated zOGR1.

  4. data identify a role for GPR68 as a proton sensor that is required for proper enamel formation

  5. coexpression of OGR1- and G2A (Montrer GPR132 Anticorps)-enhanced proton sensitivity and proton-induced calcium signals. This alteration is attributed to oligomerization of OGR1 and G2A (Montrer GPR132 Anticorps). The oligomeric potential locates receptors at a specific site, which leads to enhanced

  6. Proton-sensing GPCR (Montrer NMUR1 Anticorps)-YAP (Montrer YAP1 Anticorps) Signalling Promotes Cancer-associated Fibroblast Activation of Mesenchymal Stem Cells

  7. The deconstruction of OGR1-dependent signaling may aid our understanding of mucosal inflammation mechanisms

  8. Provide evidence for the roles of OGR1 and ASIC1a (Montrer ACCN2 Anticorps) in the regulation of intestinal passive Mg(2 (Montrer MUC7 Anticorps)+) absorption.

  9. the expression of OGR1 in myeloid-derived cells, especially in double positive cells, was required for prostate tumor cell-induced immunosuppression.

  10. The involvement of ovarian cancer G-protein-coupled receptor 1 in acidic extracellular environment may be an underlying mechanism responsible for bone pain in osteoporosis or bone metastasis without clinically proved fractures.

Mouse (Murine) G Protein-Coupled Receptor 68 (GPR68) interaction partners

  1. In rapidly growing mice, lack of OGR1 leads to increased bone mass with increased bone turnover and a greater increase in bone formation than resorption.

  2. Here, we demonstrate that metals, Fe, Zn, Co, Ni and Mn are the novel OGR1 agonists, which can singly activate OGR1 in neutral pH.

  3. CaSR (Montrer CASR Anticorps) and OGR1 reciprocally inhibit signaling through each other in central neurons, and that this is lost in their transformed counterparts. Acidification potentiates OGR1.

  4. acidic pH stimulates cGMP accumulation preferentially through the OGR1/Gq/11 proteins/phospholipase C (Montrer PLC Anticorps)/Ca(2 (Montrer CA2 Anticorps)+)/nNOS (Montrer NOS1 Anticorps) in N1E-115 neuronal cells. Akt (Montrer AKT1 Anticorps)-mediated phosphorylation of nNOS (Montrer NOS1 Anticorps)

  5. OGR1 on dendritic cells is critical for their migration to draining lymph nodes, which, in turn, stimulates Th2 phenotype change and subsequent induction of airway inflammation and hyperreactivity.

  6. Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin (Montrer INS Anticorps) secretion.

  7. OGR1 alters the pH-sensitive response of NHE and H+-ATPase (Montrer ATP6AP1 Anticorps) activity in proximal tubules.

  8. regulator of G-protein signaling 18 (Montrer RGS18 Anticorps) acts as a negative regulator of the acidosis-induced osteoclastogenic OGR1/NFAT (Montrer NFATC1 Anticorps) signaling pathway

  9. OGR1 induces an increase in Ca(i (Montrer CA1 Anticorps)) in response to acidic medium and is a prime candidate for an osteoblast proton sensor.

  10. OGR1's role in osteoclastogenesis is not strong enough to affect overall bone development.

GPR68 profil antigène

Profil protéine

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (By similarity). Function also as a metastasis suppressor gene in prostate cancer (By similarity).

Gene names and symbols associated with GPR68

  • G protein-coupled receptor 68 (GPR68) anticorps
  • G protein-coupled receptor 68 (LOC100348269) anticorps
  • G protein-coupled receptor 68 (Gpr68) anticorps
  • BB131428 anticorps
  • GPR12A anticorps
  • GPR68 anticorps
  • Ogr1 anticorps

Protein level used designations for GPR68

G protein-coupled receptor 68 , ovarian cancer G-protein coupled receptor 1-like , G-protein coupled receptor 68 , ovarian cancer G protein-coupled receptor, 1 , ovarian cancer G-protein coupled receptor 1 , sphingosylphosphorylcholine receptor , bRGR1 , g protein-coupled receptor RGR1

GENE ID SPECIES
428904 Gallus gallus
453105 Pan troglodytes
696529 Macaca mulatta
100348269 Oryctolagus cuniculus
100412989 Callithrix jacchus
100437072 Pongo abelii
100598083 Nomascus leucogenys
8111 Homo sapiens
238377 Mus musculus
314386 Rattus norvegicus
281799 Bos taurus
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