anti-GRB2-Related Adaptor Protein (GRAP) Anticorps

The protein encoded by GRAP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. De plus, nous expédions GRAP Kits (5) et GRAP Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
GRAP 363616  
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Top anti-GRAP Anticorps sur anticorps-enligne.fr

Showing 10 out of 65 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-GRAP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: THP-1 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN184595 (0.3µg/ml) staining of human thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: Grap Antibody Dilution: 1.0ug/ml Sample Type: Rat Spleen 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from 293/MCF-7/COLO cells, using GRAP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Boeuf (Vache) Chèvre Inconjugué WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$462.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using GRAP, antibody at 1:500 dilution. IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP, antibody at 1:100 dilution. 100 μL Connectez-vous pour afficher 3 to 4 Days
$466.18
Détails
Hamster Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$610.50
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails

anti-GRAP Anticorps mieux référencés

  1. Human Polyclonal GRAP Primary Antibody pour ELISA, WB - ABIN256861 : Fathi, Rasouli, Yeganeh, Salekdeh, Baharvand: Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor. dans Molecular biotechnology 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GRAP Primary Antibody pour ELISA, WB - ABIN546720 : Feng, Ouyang, Hu, Shi, Gentz, Ni: Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre GRAP partenaires d’interaction

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression.

  2. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed as a novel component of TGF-beta signaling in cultured human renal tubule cells.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2, acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 domain-containing adapters Grb2 and Grap

GRAP profil antigène

Profil protéine

This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) anticorps
  • GRB2-related adaptor protein (Grap) anticorps
  • GRB2-related adapter protein (LOC489534) anticorps
  • GRB2-related adaptor protein a (grapa) anticorps
  • GRB2-related adaptor protein b (grapb) anticorps
  • GRB2-related adapter protein (LOC100727005) anticorps
  • 8430435N19Rik anticorps
  • BB233594 anticorps
  • Grap anticorps
  • MGC109892 anticorps
  • si:dkeyp-9d4.1 anticorps
  • zgc:110202 anticorps

Protein level used designations for GRAP

GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein , GRB2-related adaptor protein

GENE ID SPECIES
10750 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
416523 Gallus gallus
489534 Canis lupus familiaris
534491 Bos taurus
553596 Danio rerio
555184 Danio rerio
100727005 Cavia porcellus
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