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The protein encoded by GRAP, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. De plus, nous expédions GRAP Protéines (5) et GRAP Kits (3) et beaucoup plus de produits pour cette protéine.
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Human Polyclonal GRAP Primary Antibody pour ELISA, WB - ABIN256861
Fathi, Rasouli, Yeganeh, Salekdeh, Baharvand: Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor. dans Molecular biotechnology 2015
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This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
GRB2-related adapter protein
, growth factor receptor-bound protein 2-related adaptor protein
, GRB2-related adaptor protein