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GIMAP6 encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. De plus, nous expédions GIMAP6 Protéines (7) et beaucoup plus de produits pour cette protéine.
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GIMAP6 plays a role in modulating immune function and that it does this by controlling cell death and the activation of T cells.
These data,demonstrating the downregulation of the mRNA and protein expression levels of GIMAP5 and GIMAP6 in the tumor tissues and blood of patients with Hepatocellular carcinoma (HCC) , suggested the involvement of GIMAP5 and GIMAP6 in the pathogenesis of HCC, and indicate their possible use as diagnostic markers for HCC.
The results indicate a requirement for GIMAP6 in the maintenance of a normal peripheral adaptive immune system and a significant role for the protein in normal autophagic processes. Moreover, as GIMAP6 is expressed in a cell-selective manner, this indicates the potential existence of a cell-restricted mode of autophagic regulation.
This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7.
GTPase, IMAP family member 6
, GTPase IMAP family member 6
, immune associated nucleotide 2
, immune associated nucleotide 6
, immune-associated nucleotide 6
, immunity-associated nucleotide 6 protein