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Receptor for gastrin releasing peptide (GRP). De plus, nous expédions GRPR Kits (6) et GRPR Protéines (6) et beaucoup plus de produits pour cette protéine.
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Bat Polyclonal GRPR Primary Antibody pour IHC (p), WB - ABIN271325
Grimsholm, Rantapää-Dahlqvist, Dalén, Forsgren et al.: Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the ... dans Neuropeptides 2008
Show all 2 Pubmed References
These data suggest that GRPR expression in fibroblast-like synoviocytes (FLS)and that exogenous GRP are able to activate FLS invasion. This effect occurs at least in part through the AKT activation. Therefore, understanding of the GRP/GRPR pathway could be relevant in the development of FLS-targeted therapy for Rheumatoid arthritis .
ablating GRP (Montrer UCMA Anticorps) receptor-expressing neurons eliminated basal and hypoxia-induced sighing, but left breathing otherwise intact initially
Together, we define the respective function of NMBR (Montrer NMBR Anticorps) and GRPR in itch transmission, and reveal an unexpected relationship not only between the two receptors but also between the two populations of interneurons in itch signaling.
BNP (Montrer BNC2 Anticorps)-NPRA (Montrer NPR1 Anticorps) signaling is involved in both itch and pain and does not function upstream of the GRP (Montrer UCMA Anticorps)-GRPR dedicated neuronal pathway.
The present results suggest that BB2 receptor-expressing spinal neurons transmit herpes-associated itch by BB2 receptor-independent signaling.
spinal GRPr and NMBr (Montrer NMBR Anticorps) independently drive itch neurotransmission in mice.
GRPR and stathmin (Montrer STMN1 Anticorps) control in opposite directions both cued fear extinction and neural activities of the amygdala and prefrontal cortex
Gastrin-releasing peptide receptor mediates chemotaxis in neutrophils, and may be an alternative chemotactic receptor playing a role in the pathogenesis of inflammatory disorders.
The data suggest that opioid-induced itch is an active process concomitant with but independent of opioid analgesia, occurring via the unidirectional cross-activation of GRPR signaling by MOR1D heterodimerization
We propose that deletion of GRPR leads to the induction of depression-like behavior which is paralleled by dysregulation of amygdala gene expression, potentially resulting from deficient light-induced corticosterone release in GRPR-knockout mice
GRP/GRP (Montrer LSM4 Anticorps)-R signaling activation contributes to castration-resistant prostate cancer progression
Expression of Gastrin-Releasing Peptide Receptor in Breast Cancer and Its Association with Pathologic, Biologic, and Clinical Parameters
Our results suggest that, similar to what happens in neutrophils, gastrin-releasing peptide (Montrer GRP Anticorps) is a migratory, rather than a proliferative, stimulus, for non-small cell lung carcinoma cells, indicating a putative role for gastrin-releasing peptide (Montrer GRP Anticorps) and gastrin-releasing peptide receptor in metastasis
GRP-R regulates glucose metabolism in neuroblastoma (Montrer ARHGEF16 Anticorps) by modulating HIF-1alpha (Montrer HIF1A Anticorps), PDK4 (Montrer PDK4 Anticorps) and PDP2 (Montrer PDP2 Anticorps).
BBS (Montrer BBS2 Anticorps) caused a significant increase in Shh (Montrer SHH Anticorps) gene transcription and protein secretion that was dependent on BBS (Montrer BBS2 Anticorps)-induced GPCR (Montrer NMUR1 Anticorps)/Galphaq (Montrer GNAQ Anticorps)-//Rho mediated activation of nuclear factor kappaB (NFkappaB (Montrer NFKB1 Anticorps)), which can stimulate a NF-kappaB (Montrer NFKB1 Anticorps) response element in the Shh (Montrer SHH Anticorps) gene promoter
No association of 16 GRP (Montrer LSM4 Anticorps) and 7 GRPR variants were found with agoraphobia with/without panic disorder.
GRPR is highly expressed in epidermoid carcinoma of the anal canal, suggesting this receptor might have a role in anal carcinogenesis.
a key mechanism for GRPR-regulated colon cancer cell migration through the Galpha13 (Montrer GNA13 Anticorps)-PRG (Montrer PRB3 Anticorps)-RhoA (Montrer RHOA Anticorps)-ROCK pathway.
GRPR expression was more pronounced in an advanced-stage lung cancer
integrin ss1 subunit critically regulates GRP-R-mediated neuroblastoma (Montrer ARHGEF16 Anticorps) cell migration and invasion
Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
gastrin-releasing peptide receptor
, gastrin-releasing peptide receptor-like
, GRP-preferring bombesin receptor
, bombesin receptor