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transcription factor; may be important for brain cell development.
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Human Polyclonal GMFB Primary Antibody pour WB - ABIN1881377
Li, Ye, Cheng, Hu, Zhou, Lü, Xie: Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer. dans European journal of cancer (Oxford, England : 1990) 2010
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Human Polyclonal GMFB Primary Antibody pour ICC, IF - ABIN4315210
Yu, Wu, Fan, Lv, Guo, Zhao, Zhou, Zhang, Wang, Xiao, Chen, Zhu, Chen, Lin, Liu, Zhou, Wang, Huo, Zhou, Sha: Evaluation of blastomere biopsy using a mouse model indicates the potential high risk of neurodegenerative disorders in the offspring. dans Molecular & cellular proteomics : MCP 2009
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GMF transgenic mice might be a novel mouse model of accelerated aging, due to the abnormal lamin A (Montrer LMNA Anticorps)
Deficiency of glia maturation factor (Montrer GMFG Anticorps) protects the dopaminergic neuron loss in a model of parkinsonism.
The data suggest that debranching by GMFbeta plays an important role in branched actin regulation, lamellipodial dynamics, and directional migration.
[glial maturation factor; GMF] Results imply that GMF is involved in the signaling leading to the activation of glycogen synthase kinase-3beta and caspase-3 (Montrer CASP3 Anticorps) in N18 cells and strongly suggest its involvement in neurodegeneration.
proteinuria induction of GMF-beta in renal proximal tubular cells may play a critical role in the progression of renal diseases by enhancing oxidative injuries
GMF-beta is an important player in glioma progression via promoting neovascularization.
The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology.
GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration.
There is a significant increase in GMF beta protein expression levels in IFN beta (Montrer IFNB1 Anticorps)-1a treated LX-2 cells.
GMFB promoted T-cell differentiation into CD4 (Montrer CD4 Anticorps)-/CD8 (Montrer CD8A Anticorps)+ cells when analysed by two-colour flow cytometry.
transcription factor; may be important for brain cell development
glia maturation factor beta
, glia maturation factor, beta
, Glia maturation factor beta
, DNA for thyroid hormone receptor binding site (276bp)
, uncharacterized protein LOC495362