anti-Glicentin-related polypeptide (GRPP) Anticorps

The protein encoded by GRPP is actually a preproprotein that is cleaved into four distinct mature peptides.

afficher tous les anticorps Gène GeneID UniProt
GRPP 2641 P01275
GRPP 14526 P55095
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Top anti-Glicentin-related polypeptide Anticorps sur

Showing 10 out of 12 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Souris Lapin Inconjugué IF (p), IHC (p)   100 μL Connectez-vous pour afficher 3 to 7 Days
Humain Lapin Carboxyfluorescein (CFS) ELISA   100 μL Connectez-vous pour afficher 16 Days
Humain Lapin Inconjugué ELISA   200 μg Connectez-vous pour afficher 11 to 16 Days
Humain Lapin Biotin ELISA   100 μL Connectez-vous pour afficher 16 Days
Humain Lapin Inconjugué IHC   100 μL Connectez-vous pour afficher 13 to 15 Days
Humain Lapin Inconjugué WB   200 μg Connectez-vous pour afficher 13 to 15 Days
Humain Lapin FITC   100 μL Connectez-vous pour afficher 13 to 15 Days
Humain Lapin Biotin   100 μL Connectez-vous pour afficher 13 to 15 Days
Humain Lapin FAM   100 μL Connectez-vous pour afficher 13 to 15 Days
Humain Lapin DyLight 647   100 μL Connectez-vous pour afficher 13 to 15 Days

GRPP Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,

, , , , , ,
Mouse (Murine)

Rat (Rattus)

Plus d’anticorps contre Glicentin-related polypeptide partenaires d’interaction

Human Glicentin-related polypeptide (GRPP) interaction partners

  1. This review summarizes the current knowledge regarding the role of GLP-1 (Montrer GCG Anticorps) in the protection against oxidative damage and the activation of the Nrf2 (Montrer GABPA Anticorps) signaling pathway. [review]

  2. Study concludes that in healthy subjects, glucagon-like peptide-1 (GLP-1 (Montrer GCG Anticorps)) increases cardiac output acutely due to a GLP-1 (Montrer GCG Anticorps)-induced vasodilation in adipose tissue and skeletal muscle together with an increase in cardiac work.

  3. Chenodeoxycholic acid stimulates glucagon-like peptide-1 (Montrer GCG Anticorps) secretion in patients after Roux-en-Y gastric bypass.

  4. The results demonstrate that glucagon-like peptide-1 (Montrer GCG Anticorps) and insulin (Montrer INS Anticorps) synergistically and additively activate vagal afferent neurons.

  5. DPP-4 (Montrer DPP4 Anticorps) activity and GLP (Montrer RCBTB1 Anticorps)-1total levels were higher in patients with microvascular complications associated with T2DM. Contrary to expectations, no negative correlation was seen between GLP-1 (Montrer GCG Anticorps) and DDP (Montrer TIMM8A Anticorps)-4 levels. This result suggests the possible inefficacy of DDP (Montrer TIMM8A Anticorps)-4 activity as a marker to predict in vivo degradation of endogenous GLP-1 (Montrer GCG Anticorps).

  6. Data suggest that cAMP acts as amplifier of insulin (Montrer INS Anticorps) secretion triggered by Ca2 (Montrer CA2 Anticorps)+ elevation in beta-cells; both messengers are also positive modulators of glucagon (Montrer GCG Anticorps) release from alpha-cells, but in this case cAMP signaling may be the important regulator and Ca2 (Montrer CA2 Anticorps)+ signaling has a more permissive role. [REVIEW]

  7. This study provides evidence that, in HepG2 cells, GLP-1 (Montrer GCG Anticorps) may affect cholesterol homeostasis by regulating the expression of miR (Montrer MLXIP Anticorps)-758 and ABCA1 (Montrer ABCA1 Anticorps).

  8. This study reports the transition dipole strengths and frequencies of the amyloid beta-sheet amide I mode for the aggregated proteins amyloid-beta1-40, calcitonin (Montrer CALCA Anticorps), alpha-synuclein, and glucagon (Montrer GCG Anticorps).

  9. genetic association studies in population in China: Data confirm that an SNP in an intron of SLC47A1 (Montrer SLC47A1 Anticorps) (rs2289669) is associated with hypoglycemic response to metformin in patients with newly diagnosed type 2 diabetes; differential increases in basal GLP1 (Montrer GCG Anticorps) plasma levels are also related to this SNP. (SLC47A1 (Montrer SLC47A1 Anticorps) = solute carrier family 47 member 1 (Montrer SLC47A1 Anticorps); GLP1 (Montrer GCG Anticorps) = glucagon-like peptide-1 (Montrer GCG Anticorps))

  10. GLP-2 (Montrer GCG Anticorps) augmented BRIN BD11 (Montrer DEFB110 Anticorps) beta-cell proliferation, but was less efficacious in 1.1B4 cells. These data highlight the involvement of GLP-2 receptor (Montrer GLP2R Anticorps) signalling in the adaptations to pancreatic islet cell stress.

Mouse (Murine) Glicentin-related polypeptide (GRPP) interaction partners

  1. FXR (Montrer NR1H4 Anticorps) exerts its function in L cells through interacting with CREB (Montrer CREB1 Anticorps), a crucial transcriptional regulator of cAMP-CREB (Montrer CREB1 Anticorps) signaling pathway, to inhibit its transcriptional activity. Targeting FXR (Montrer NR1H4 Anticorps) to rescue GLP-1 (Montrer GCG Anticorps) secretion may be a promising strategy for type II diabetes.

  2. results show that glucagon (Montrer GCG Anticorps) controls gene expression and metabolic zonation in the liver through a counterplay with the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway.

  3. Data (including data from studies using transgenic and knockout mice) suggest that Glp1 (Montrer GCG Anticorps)/Glp1r (Montrer GLP1R Anticorps) signaling in insulin (Montrer INS Anticorps)-secreting cells plays important role in development of glucose intolerance in obesity; however, Glp1r (Montrer GLP1R Anticorps) is not required in insulin (Montrer INS Anticorps)-secreting cells for improvement in glucose intolerance after weight loss due to bariatric surgery (here, vertical sleeve gastrectomy).

  4. Chronic stress accelerates DPP4-mediated GLP-1 degradation and alters plasma adiponectin, accelerating vascular senescence and impairing ischemia-induced neovascularization.

  5. Data suggest that metabolism of glutamine (Montrer GFPT1 Anticorps) and related analogs by Gdh (Montrer UGDH Anticorps) in intestinal L-cells explains why Glp1 (Montrer GCG Anticorps) secretion, but not that of insulin (Montrer INS Anticorps) by pancreatic beta-cells, is activated by these secretagogues. (Gdh (Montrer UGDH Anticorps) = glutamate (Montrer GRIN1 Anticorps) dehydrogenase; Glp1 (Montrer GCG Anticorps) = glucagon-like peptide 1 (Montrer GCG Anticorps))

  6. Glucokinase (Montrer GCK Anticorps) governs an alpha-cell metabolic pathway that suppresses secretion at or above normoglycemic levels; abnormal suppression of glucagon (Montrer GCG Anticorps) secretion deregulates hepatic glucose metabolism and, over time, induces a pre-diabetic phenotype.

  7. in colonic crypt cultures, the GLP-1 (Montrer GCG Anticorps) secretion induced by such Gq + Gs GPR40 (Montrer FFAR1 Anticorps) agonists is indeed inhibited by blockers of both Gq and Gs and is eliminated by combining these.

  8. Enteric GLP-1 (Montrer GCG Anticorps) activates NO production by enteric neurons that is impaired in type 2 diabetes. Gut (Montrer GUSB Anticorps) microbiota dysbiosis induces enteric neuropathy. Gut (Montrer GUSB Anticorps) microbiota dysbiosis is responsible for the GLP-1 (Montrer GCG Anticorps) resistance.

  9. of glucagon-like peptide-1 (Montrer GCG Anticorps) in vagotomized mice may prevent VLDL overproduction and insulin (Montrer INS Anticorps) resistance induced by high-fat diet.

  10. beta-cell function, plasma active GLP-1 (Montrer GCG Anticorps) levels, the GLP-1R (Montrer GLP1R Anticorps) pathway in beta cells and L cell differentiation, were investigated.

Glicentin-related polypeptide (GRPP) profil antigène

Profil protéine

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Gene names and symbols associated with GRPP

  • glucagon (GCG) anticorps
  • glucagon (Gcg) anticorps
  • GLP-1 anticorps
  • GLP1 anticorps
  • GLP2 anticorps
  • Glu anticorps
  • GRPP anticorps
  • PPG anticorps

Protein level used designations for GRPP

glicentin-related polypeptide , glucagon-like peptide 1 , glucagon-like peptide 2 , preproglucagon , glucagon-like peptide I

2641 Homo sapiens
14526 Mus musculus
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