anti-Glucose-6-Phosphate Isomerase (GPI) Anticorps

GPI belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. De plus, nous expédions Glucose-6-Phosphate Isomerase Kits (68) et Glucose-6-Phosphate Isomerase Protéines (59) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GPI 292804 Q6P6V0
GPI 14751 P06745
GPI 2821 P06744
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Top anti-Glucose-6-Phosphate Isomerase Anticorps sur anticorps-enligne.fr

Showing 10 out of 230 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB GPI Antibody (C-term) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. GPI Antibody (C-term) western blot analysis in A2058,Y79,Ramos,A375,K562 and mouse Neuro-2a cell line lysates (35µg/lane).This demonstrates the GPI antibody detected the GPI protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Souris Inconjugué ELISA, ICC, IHC, WB Figure 1: Western blot analysis using GPI mouse mAb against HepG2 (1) , SMMC-7721 (2) cell lysate and rat liver tissues lysate (3). Dilution: 1/500 - 1/2000 Figure 2: Western blot analysis using GPI mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY GPI cDNA (2). Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 10 to 11 Days
$577.50
Détails
Humain Lapin Inconjugué WB Western blot analysis of GPI expression in human placenta extract ( Lane 1) and JURKAT whole cell lysates ( Lane 2). GPI at 63KD was detected using rabbit anti- GPI Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Souris Lapin Inconjugué WB Western blot analysis of GPI expression in mouse thymus extract ( Lane 1). GPI at 64KD was detected using rabbit anti- GPI Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Glucose 6 phosphate isomerase Antibody [NBP1-90177] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli, plasma membrane & cytoplasm. Immunohistochemistry-Paraffin: Glucose 6 phosphate isomerase Antibody [NBP1-90177] - Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB ABIN571080 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. ABIN571080 (0.05µg/ml) staining of HeLa (A), A431 (B), A549 (C), MCF7 (D), Jurkat (E) and K562 (F) lysates (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails

anti-Glucose-6-Phosphate Isomerase Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal GPI Primary Antibody pour WB - ABIN1881382 : Benveniste, Frelin, Janmohamed, Barbara, Herrington, Hyam, Iscove: Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential. dans Cell stem cell 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal GPI Primary Antibody pour ICC, IHC - ABIN969176 : Muraki, Matsumoto, Chino, Hayashi, Suzuki, Goto, Ito, Murata, Tsutsumi, Sumida: Glucose-6-phosphate isomerase variants play a key role in the generation of anti-GPI antibodies: possible mechanism of autoantibody production. dans Biochemical and biophysical research communications 2004 (PubMed)
    Show all 3 Pubmed References

  3. Dog (Canine) Polyclonal GPI Primary Antibody pour WB - ABIN611563 : Ohashi, Burkart, Flohé, Kolb: Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. dans Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal GPI Primary Antibody pour ELISA, ICC - ABIN5682732 : Lucarelli, Galleggiante, Rutigliano, Sanguedolce, Cagiano, Bufo, Lastilla, Maiorano, Ribatti, Giglio, Serino, Vavallo, Bettocchi, Selvaggi, Battaglia, Ditonno: Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma. dans Oncotarget 2015 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal GPI Primary Antibody pour FACS, WB - ABIN653743 : Jiang, Wang, Wang, Xu, Xu, Tang, Sun, Wang, Zhang: Enolase1 (ENO1) and glucose-6-phosphate isomerase (GPI) are good markers to predict human sperm freezability. dans Cryobiology 2015 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal GPI Primary Antibody pour ICC, IF - ABIN4314558 : Wu, Hsu, Chen, Yu, Chang, Tai, Liu, Su, Chang, Yu: Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. dans Molecular & cellular proteomics : MCP 2010 (PubMed)

Plus d’anticorps contre Glucose-6-Phosphate Isomerase partenaires d’interaction

Mouse (Murine) Glucose-6-Phosphate Isomerase (GPI) interaction partners

  1. PGI is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.

  2. The mGPI-transgenic mice presented GPI more efficiently and showed a dramatic increase in negative selection and an inhibition of arthritis.

  3. Increased red cell turnover in a line of CD22-deficient mice is caused by Gpi1c: a model for hereditary haemolytic anaemia.

  4. Data show that silencing of AMF/PGI induced MET and suppressed the tumor growth and pulmonary metastasis of LM8 cells in nude mice.

  5. induces hyperpermeability of endothelial and mesothelial cells leading to accumulation of ascites fluid (tumor autocrine motility factor)

  6. acid-induced conformational changes in phosphoglucose isomerase result in its increased cell surface association and deposition on fibronectin fibrils

  7. Gpi1 immunoreactivity was found in ganglion, amacrine, horizontal and bipolar cells, but not in rods, cones, pigment epithelium and Muller cells.

  8. High-resolution crystal structures of the enzyme from mouse have been determined in native form and in complex with the inhibitor erythrose 4-phosphate, and with the substrate glucose 6-phosphate.

  9. crystal structure of Autocrine Motility Factor

  10. AMF expression significantly contributes to the aggressive phenotype of pancreatic cancer

  11. Results report the first high-resolution crystal structure of the inhibitor-free form and the eight types of inhibitor complexes of mouse autocrine motility factor.

  12. the receptor molecule for AMF/NLK/MF in leukemic differentiation is not gp78

Human Glucose-6-Phosphate Isomerase (GPI) interaction partners

  1. we describe new p.(Arg472Cys) and p.(Ser160Pro) GPI mutations in the first cases of GPI deficiency in the Czech and Slovak populations.

  2. Study demonstrated a novel pathway regulating hypoxia-induced angiogenesis in rheumatoid arthritis mediated by glucose-6-phosphate isomerase.

  3. Our data suggest that glucose-6-phosphate isomerase gene polymorphism may serve as potential biomarkers to predict the overall survival of hepatocellular carcinoma.

  4. Mutation p.Gln413Arg fs*24 is the first frameshift null mutation to be described in GPI deficiency. Molecular modeling suggests that the structural change induced by the p.Gly87Ala pathogenic variant has direct impact in the structural arrangement of the region close to the active site of the enzyme.

  5. The 2 cysteines in hGPIc-c are prone to form disulfides upon oxidation. hGPIc-c could induce arthritis in both B10.Q and B10Q.Ncf1*/* mice, whereas hGPIs-s immunization did not induce disease at all, showing that these disulfides are critical for the arthritis-inducing immune response. The cysteines at position 330 and 333 are not crucial for TCR recognition. GILT expression affects hGPI-c-c processing at the CXXC motif.

  6. These results suggested that E4P by directly interacting with extracellular HPI/AMF may be an effective strategy to deter BCSC growth and progression.

  7. The silencing of PGI/AMF decreased the levels of phosphorylated Akt (-71.9%, P<0.001) compared with the scrambled siRNA, as well as the levels of the stemness marker, SOX2 (-61.7%, P<0.01). Taken together, these findings suggest that PGI/AMF silencing decreases migration, tumorsphere formation as well as the proportion of on the side population cells in glioblastoma U87 cells.

  8. NLK is able to promote cell proliferation and type II collagen synthesis during in vitro chondrocyte propagation.

  9. Suggest tha AMF/PGI-mediated tumorigenesis occurs through MAPK-ERK signaling in endometrial carcinoma.

  10. Study supports a role for AMF mediating epithelial-mesenchymal transition in endometrial cancer (EC) through MAPK signaling. Therefore, AMF may provide a potential prognostic and therapeutic target in preventing EC progression.

  11. Results showed an increase in GPI and AMFR in clear cell-renal cell carcinoma cells, and their colocalization on plasma membrane. Kaplan-Meier curves showed significant differences in survival among groups of patients with high versus low GPI.

  12. The association of ENO1 and GPI with postthaw sperm viability and motility was confirmed using Pearson's linear correlation. ENO1 and GPI can be used as markers of human sperm freezability before starting the cryopreservation procedure.

  13. High GPI expression is associated with metastatic phenotype of breast cancer.

  14. PGI is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.

  15. Serum anti-GPI autoantibodies are useful for the diagnosis of rheumatoid arthritis in Chinese patients.

  16. Findings suggest that autocrine motility factor (AMF)-HER2 interaction might be a novel target for therapeutic management of patients with breast cancer, whose disease is resistant to trastuzumab.

  17. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

  18. For PGI, an extended active site in which residues in the first, second, and third layers around the reacting substrate are predicted.

  19. GPI is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.

  20. By regulating ER calcium release, AMF/PGI interaction with gp78/AMFR therefore protects against ER stress identifying novel roles for these cancer-associated proteins in promoting tumor cell survival.

Zebrafish Glucose-6-Phosphate Isomerase (GPI) interaction partners

  1. The differential expression of gpia and gpib in zebrafish suggests partition or divergence of gpi functions between the two duplicates.

  2. Comparison of glucose phosphase isomerase (GPI) genes from several vertebrates suggests that GPIs are being subjected to purifying selection to maintain the polarity and volume of the protein, but not its charge.

Glucose-6-Phosphate Isomerase (GPI) profil antigène

Profil protéine

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Gene names and symbols associated with GPI

  • glucose-6-phosphate isomerase (GPI) anticorps
  • glucose-6-phosphate isomerase (Gpi) anticorps
  • glucose-6-phosphate isomerase (gpi) anticorps
  • gpi (pgi) anticorps
  • glucose-6-phosphate isomerase 1 (GPI1) anticorps
  • gpi Glucose-6-phosphate isomerase (gpi) anticorps
  • Phosphoglucose isomerase (Pgi) anticorps
  • glucose phosphate isomerase 1 (Gpi1) anticorps
  • glucose-6-phosphate isomerase b (gpib) anticorps
  • AMF anticorps
  • CG8251 anticorps
  • DDBDRAFT_0185620 anticorps
  • DDBDRAFT_0231026 anticorps
  • DDB_0185620 anticorps
  • DDB_0231026 anticorps
  • Dmel\\CG8251 anticorps
  • GNPI anticorps
  • gpi anticorps
  • Gpi-1 anticorps
  • Gpi-1r anticorps
  • Gpi-1s anticorps
  • Gpi-1t anticorps
  • Gpi1 anticorps
  • Gpi1-r anticorps
  • Gpi1-s anticorps
  • Gpi1-t anticorps
  • Gpi1s anticorps
  • MF anticorps
  • NK anticorps
  • NK/GPI anticorps
  • NLK anticorps
  • Org anticorps
  • pgi anticorps
  • pgi-2 anticorps
  • PHI anticorps
  • SA-36 anticorps
  • SA36 anticorps

Protein level used designations for GPI

AMF , NLK , PHI , autocrine motility factor , glucose phosphate isomerase , muscle phosphohexose isomerase , neuroleukin , phosphoglucose isomerase , phosphohexose isomerase , PGI , glucosephosphate isomerase , glucose-6-phosphate isomerase , gpi Glucose-6-phosphate isomerase , CG8251-PA , CG8251-PB , CG8251-PC , Pgi-PA , Pgi-PB , Pgi-PC , phosphoglucoisomerase , glucose phosphate isomerase 1 complex , glucose phosphate isomerase 1, regulatory , glucose phosphate isomerase 1, structural , glucose phosphate isomerase 1, temporal , maturation factor , structural glucose phosphate isomerase 1 , hexose monophosphate isomerase , hexosephosphate isomerase , oxoisomerase , phosphohexomutase , phosphosaccharomutase , sperm antigen 36 , sperm antigen-36 , glucose phosphate isomerase b

GENE ID SPECIES
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292804 Rattus norvegicus
415783 Gallus gallus
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692243 Hordeum vulgare
3117706 Legionella pneumophila str. Paris
1022330 Bifidobacterium longum NCC2705
7997113 Bartonella grahamii as4aup
543945 Solanum lycopersicum
780596 Triticum aestivum
1089499 Tropheryma whipplei str. Twist
8624197 Dictyostelium discoideum AX4
8691155 Bifidobacterium dentium Bd1
100008744 Oryctolagus cuniculus
35886 Drosophila melanogaster
611942 Canis lupus familiaris
14751 Mus musculus
2821 Homo sapiens
100057160 Equus caballus
100719769 Cavia porcellus
246095 Danio rerio
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