anti-Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) Anticorps

GPT2 encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain GPT2 GPT2 84706 Q8TD30
Anti-Rat GPT2 GPT2 307759  
Anti-Souris GPT2 GPT2 108682 Q8BGT5
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Top anti-GPT2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 66 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-GPT2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), SimWes, WB Immunohistochemistry-Paraffin: GPT2 Antibody [NBP2-14072] - Staining of human kidney shows distinct cytoplasmic positivity in cells in tubules. Simple Western: GPT2 Antibody [NBP2-14072] - Simple Western lane view shows a specific band for GPT2 in 0.2 mg/ml of HepG2 (left) and h. Kidney (right) lysate(s). This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$491.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of ALT2 expression in SHSY5Y (A), HepG2 (B), HEK293T (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB GPT2 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GPT2 antibody detected the GPT2 protein (arrow). GPT2 Antibody (N-term)  western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the GPT2 antibody detected the GPT2 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Souris Inconjugué IF, ELISA, WB Western Blot analysis of GPT2 expression in transfected 293T cell line by GPT2 monoclonal antibody (M04), clone 7A11.<br><br>Lane 1: GPT2 transfected lysate (Predicted MW: 57.9 KDa).<br>Lane 2: Non-transfected lysate.<br> Detection limit for recombinant GST tagged GPT2 is 1 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué IF, IP, IHC, WB Western blot analysis of extracts of HepG2 and mouse kidney cell lines, using GPT2 antibody. 100 μL Connectez-vous pour afficher 16 Days
$476.15
Détails
Rat Lapin Inconjugué IHC (p), ELISA Immunochemical staining of rat GPT2 in rat brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary an Immunochemical staining of rat GPT2 in rat liver with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Connectez-vous pour afficher 20 to 21 Days
$218.90
Détails
Humain Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Human Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Human ALT2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 15 to 18 Days
$350.00
Détails
Souris Lapin Inconjugué ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Connectez-vous pour afficher 13 to 16 Days
$360.00
Détails

Plus d’anticorps contre GPT2 partenaires d’interaction

Human Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) interaction partners

  1. GPT2 reduced alpha-ketoglutarate level in cells leading to the inhibition of proline hydroxylase 2 (PHD2 (Montrer EGLN1 Anticorps)) activity involved in the regulation of HIF1alpha (Montrer HIF1A Anticorps) stability. Accumulation of HIF1alpha (Montrer HIF1A Anticorps), resulting from GPT2-alpha-ketoglutarate-PHD2 (Montrer EGLN1 Anticorps) axis, constitutively activates sonic hedgehog (Shh (Montrer SHH Anticorps)) signaling pathway.

  2. The GPT2 gene demonstrates increasing expression in brain in the early postnatal period, and GPT2 protein localizes to mitochondria. Akin to the human phenotype, Gpt2-null mice exhibit reduced brain growth. Through metabolomics and direct isotope tracing experiments, we find a number of metabolic abnormalities associated with loss of Gpt2

  3. Recessively inherited loss of function GPT2 mutations are a novel cause of intellectual disability.

  4. ATF4 (Montrer ATF4 Anticorps) silencing prevented the activating effect of histidinol and tunicamycin on ATF4 (Montrer ATF4 Anticorps) and ALT2 expression. Our findings point to ALT2 as an enzyme involved in the metabolic adaptation of the cell to stress

  5. expression of GPT2 especially in muscle and fat, suggests a unique and previously unrecognized role of this gene product in glucose, amino acid, and fatty acid metabolism and homeostasis.

  6. The biliary IL-6 (Montrer IL6 Anticorps) and TNF-alpha (Montrer TNF Anticorps) levels were positively correlated with serum DBIL, TBA and gamma-GT levels in infantile hepatitis syndrome subjects.

  7. Elevation of liver enzymes and hepatic insulin (Montrer INS Anticorps) resistance as reflected by fasting insulin (Montrer INS Anticorps) occur in the early stages of insulin (Montrer INS Anticorps) resistance and highlight the central role of the liver in insulin (Montrer INS Anticorps) resistance in the general population.

  8. A clinical method for selective measurement of ALT1 (Montrer ALT Anticorps) and 2 in human plasma is described.

Mouse (Murine) Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2) interaction partners

  1. The GPT2 gene demonstrates increasing expression in brain in the early postnatal period, and GPT2 protein localizes to mitochondria. Akin to the human phenotype, Gpt2-null mice exhibit reduced brain growth. Through metabolomics and direct isotope tracing experiments, we find a number of metabolic abnormalities associated with loss of Gpt2

  2. Data suggest that Alt2/Gpt2 (but not Alt1/Gpt1 (Montrer ALT Anticorps)) is induced in liver of obese mice (male ob/ob mice compared to lean C57BL/6J mice).

GPT2 profil antigène

Profil protéine

This gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GPT2

  • glutamic--pyruvic transaminase 2 (GPT2) anticorps
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 L homeolog (gpt2.L) anticorps
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 (gpt2) anticorps
  • alanine aminotransferase 2 (PTRG_06494) anticorps
  • glutamic--pyruvic transaminase 2 (Gpt2) anticorps
  • glutamic--pyruvic transaminase 2 (gpt2) anticorps
  • glutamic pyruvate transaminase (alanine aminotransferase) 2 (Gpt2) anticorps
  • 4631422C05Rik anticorps
  • ALT2 anticorps
  • AU014768 anticorps
  • AU041193 anticorps
  • C87201 anticorps
  • Cc2-5 anticorps
  • GPT2 anticorps
  • im:7150662 anticorps
  • sb:cb580 anticorps
  • zgc:165657 anticorps

Protein level used designations for GPT2

GPT 2 , alanine aminotransferase 2 , glutamate pyruvate transaminase 2 , glutamic--alanine transaminase 2 , glutamic--pyruvic transaminase 2 , glutamic-pyruvate transaminase 2 , glutamic pyruvate transaminase (alanine aminotransferase) 2 , ALT2 , glutamic pyruvate transaminase 2 , alanine aminotransferase 2-like

GENE ID SPECIES
84706 Homo sapiens
100056741 Equus caballus
618400 Bos taurus
444533 Xenopus laevis
415746 Gallus gallus
799963 Danio rerio
549559 Xenopus (Silurana) tropicalis
6344753 Pyrenophora tritici-repentis Pt-1C-BFP
307759 Rattus norvegicus
100521318 Sus scrofa
100550762 Meleagris gallopavo
100558944 Anolis carolinensis
100601247 Nomascus leucogenys
108682 Mus musculus
100724098 Cavia porcellus
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