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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. De plus, nous expédions Glutathione S-Transferase alpha 3 Kits (23) et Glutathione S-Transferase alpha 3 Protéines (14) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 134 products:
Human Polyclonal GSTA3 Primary Antibody pour IF (p), IHC (p) - ABIN755767
Li, He, Zhang, Miao: Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes. dans Toxicology letters 2014
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Human Polyclonal GSTA3 Primary Antibody pour IHC, IHC (p) - ABIN4316399
Larsson, Mannervik, Raffalli-Mathieu: Quantitative and selective polymerase chain reaction analysis of highly similar human alpha-class glutathione transferases. dans Analytical biochemistry 2011
GSTA3 expression is significantly downregulated in human masticatory mucosa during wound healing
Density functional theory calculations used to propose a refined mechanism for the isomerization of delta(5)-androstene-3,17-dione catalyzed by GST A3-3
analysis of how isomerization of the steroid Delta(5)-androstene-3,17-dione by the glutathione transferase A3-3
Data indicate that steroidogenic factor 1 (SF-1 (Montrer NR5A1 Anticorps)) and glutathione S-transferase A (GSTA (Montrer GSTa2 Anticorps)) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.
The 3D structures of human GSTs (Montrer GSTa2 Anticorps) A2-2 and A3-3 in complex with Delta(4)-androstene-3-17-dione, were solved.
describe an I71L polymorphism in GSTA3 that occurs at a low frequency in African populations
Significantly contributes to the double-bond isomerization necessary for steroid hormone biosynthesis in complex systems, thereby complementing the indispensable 3beta-hydroxysteroid oxidoreductase activity of 3beta-hydroxysteroid dehydrogenase.
aflatoxin B1 induces cholangiocarcinomas in GSTA3-/- mice
There were no significant compensatory changes in KO mice GST subunits, GST enzymatic activity, epoxide hydrolase (Montrer EPHA2 Anticorps), or CYP1A2 (Montrer CYP1A1 Anticorps) and CYP3A11 levels. Finally, there was a modest increase in F2-isoprostane and isofuran in KO mice that confirmed putative GSTA3 hydroperoxidase activity in vivo for the first time.
Reporter gene assays demonstrated that mouse GSTA3 5(')-upstream region is activated by 15-deoxy-Delta(12,14)-prostaglandin J2 through an antioxidant response element, and that this may be involved in regulating GSTA3 expression during adipogenesis.
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
glutathione S-transferase alpha 3
, glutathione S-transferase A1
, glutathione S-transferase alpha 1
, GST class-alpha member 1
, glutathione S-transferase alpha-1
, GST class-alpha member 3
, S-(hydroxyalkyl)glutathione lyase A3
, glutathione S-alkyltransferase A3
, glutathione S-aralkyltransferase A3
, glutathione S-aryltransferase A3
, glutathione S-transferase A3
, glutathione S-transferase A3-3
, glutathione S-transferase A3-3 (GST class-alpha)
, glutathione S-transferase alpha 2
, glutathione S-transferase alpha class A3
, glutathione S-transferase Ya3
, glutathione S-transferase Yc
, GST A5-5
, GST Yc2
, glutathione S-transferase Yc-2
, glutathione S-transferase alpha-5
, GST class-alpha
, alpha II
, glutathione S-transferase alpha II