Glutathione S-Transferase mu 3 (Brain) Protéines (GSTM3)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. De plus, nous expédions Glutathione S-Transferase mu 3 (Brain) Anticorps (62) et Glutathione S-Transferase mu 3 (Brain) Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
GSTM3 2947 P21266
GSTM3 14864 P19639
Rat GSTM3 GSTM3 108348148 Q9Z1B2;
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Top Glutathione S-Transferase mu 3 (Brain) Protéines sur anticorps-enligne.fr

Showing 6 out of 8 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain Inconjugué 100 μg Connectez-vous pour afficher 2 to 3 Days
$295.00
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Escherichia coli (E. coli) Humain His tag,T7 tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$560.00
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$400.00
Détails

GSTM3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Glutathione S-Transferase mu 3 (Brain) (GSTM3) partenaires d'interaction

Human Glutathione S-Transferase mu 3 (Brain) (GSTM3) interaction partners

  1. Differential activity of antioxidant enzymes caused by the polymorphism in GSTM3 may contribute to resistance to hormonal therapy through oxidative stress. The GSTM3 rs7483 polymorphism may be a promising biomarker for prostate cancer patients treated with androgen-deprivation therapy (ADT)

  2. The individuals carrying the deletions of GSTM1 (Montrer GSTM1 Protéines) and GSTT1 (Montrer GSTT1 Protéines) were at risk for Neurocysticercosis (NCC (Montrer SLC12A3 Protéines)). Genetic variants of GSTM3 and GSTP1 (Montrer GSTP1 Protéines) were not associated with NCC (Montrer SLC12A3 Protéines).

  3. Expression of GSTM3 might be regulated by epigenetic changes in lens tissue. Hypermethylation in GSTM3 promoter and altered histone modification might have a role in the ARC (Montrer NOL3 Protéines) formation.

  4. This meta-analysis suggested that the GSTT1 (Montrer GSTT1 Protéines) and GSTM3 polymorphisms might influence osteosarcoma risk.

  5. No associations between the GSTT1, GSTP1, and GSTM3 genotypes and neoplasia risk were observed. In conclusion, we determined the genotype distribution of GST polymorphisms in control subjects and breast cancer patients from northeastern Mexico.

  6. NSD1 interacted with RNAPII and bound to GSTM3 -63A/C TATA box.

  7. To identify the genotypes of CYP1A1 (Montrer CYP1A1 Protéines), GSTM1 (Montrer GSTM1 Protéines), GSTM3, GSTT1 (Montrer GSTT1 Protéines) and GSTP1 (Montrer GSTP1 Protéines) in a case-control study.

  8. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (Montrer FXYD3 Protéines) (p = 0.0110), S100A11 (Montrer S100A11 Protéines) (p = 0.0071), and GSTM3 (p = 0.0173) in colon cancer lymphatic metastasis.

  9. This meta-analysis suggests that the GSTM3 A/B polymorphism may be an important protective factor for head and neck cancer, especially of laryngeal cancer and Caucasian populations.

  10. rs1332018 genetic variants in the GSTM3 promoter predispose the host to downregulating GSTM3 expression in kidney, facilitate carcinogenesis, and predict an unfavourable postoperative prognosis of renal cell carcinoma (Montrer MOK Protéines).

Mouse (Murine) Glutathione S-Transferase mu 3 (Brain) (GSTM3) interaction partners

  1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 (Montrer NFE2L2 Protéines) regulation: cytochrome CYP2A5, GSTM3, GSTM1 (Montrer GSTM1 Protéines), ENTPD5 (Montrer ENTPD5 Protéines),UDPGDH (Montrer UGDH Protéines), and EPHX1 (Montrer EPHX1 Protéines).

  2. Data show that beta-catenin (Montrer CTNNB1 Protéines) accumulation increases GST activity in nuclei of HCC (Montrer FAM126A Protéines) cells, and suggest that GSTM3 may be a novel target gene of the beta-catenin (Montrer CTNNB1 Protéines)/Tcf (Montrer HNF4A Protéines)-Lef complex.

Profil protéine Glutathione S-Transferase mu 3 (Brain) (GSTM3)

Profil protéine

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GSTM3

  • glutathione S-transferase mu 3 (GSTM3)
  • glutathione S-transferase Mu 3 (GSTM3)
  • glutathione S-transferase, mu 3 (Gstm3)
  • glutathione S-transferase Mu 3 (LOC479911)
  • glutathione S-transferase mu 3 (Gstm3)
  • Fsc2 Protéine
  • GST5 Protéine
  • GSTB Protéine
  • GSTM3-3 Protéine
  • GTM3 Protéine
  • mGSTM5 Protéine

Protein level used designations for GSTM3

GST class-mu 3 , S-(hydroxyalkyl)glutathione lyase M3 , brain GST , brain type mu-glutathione S-transferase , glutathione S-alkyltransferase M3 , glutathione S-aralkyltransferase M3 , glutathione S-aryltransferase M3 , glutathione S-transferase M3 (brain) , glutathione S-transferase Mu 3 , glutathione S-transferase, Mu-3 , hGSTM3-3 , glutathione S-transferase M3 , glutathione S-transferase GT9.3 , glutathione S-transferase mu 3 , glutathione-S-transferase, mu , glutathione S-transferase Mu 3-like , glutathione S-transferase Mu 5 , GST class-mu 5

GENE ID SPECIES
2947 Homo sapiens
100169963 Felis catus
14864 Mus musculus
615507 Bos taurus
457128 Pan troglodytes
479911 Canis lupus familiaris
700303 Macaca mulatta
100061826 Equus caballus
100514231 Sus scrofa
100356052 Oryctolagus cuniculus
100732625 Cavia porcellus
102188913 Capra hircus
108348148 Rattus norvegicus
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