anti-Golgin, RAB6-Interacting (GORAB) Anticorps

GORAB encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. De plus, nous expédions Golgin, RAB6-Interacting Kits (7) et Golgin, RAB6-Interacting Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GORAB 92344 Q5T7V8
GORAB 98376 Q8BRM2
GORAB 304923 B1H222
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Top anti-Golgin, RAB6-Interacting Anticorps sur anticorps-enligne.fr

Showing 10 out of 84 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: SCYL1BP1 Antibody [NBP1-92370] - Staining of human cell line A-431 shows positivity in nucleus, nucleoli, cytoplasm & golgi apparatus. Immunohistochemistry-Paraffin: SCYL1BP1 Antibody [NBP1-92370] - Staining of human kidney shows distinct positivity in glomeruli and tubular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of GORAB Antibody (N-term) in CHO cell line lysates (35µg/lane). GORAB (arrow) was detected using the purified Pab. Western blot analysis of GORAB Antibody (N-term) in mouse NIH-3T3 cell line lysates (35µg/lane). GORAB (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris Inconjugué FACS, IF, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Souris Inconjugué FACS, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Souris Inconjugué WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué WB Western blot analysis of GORAB Antibody (N-term) (ABIN653169) in CHO cell line lysates (35 µg/lane). GORAB (arrow) was detected using the purified polyclonal antibody. Western blot analysis of GORAB Antibody (N-term) (ABIN653169) in mouse NIH-3T3 cell line lysates (35 µg/lane). GORAB (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ICC, IHC (p), WB Anti-SCYL1BP1 antibody, IHC(P) IHC(P): Adenocarcinoma Metastatic Tissue Anti-SCYL1BP1 antibody, Western blotting WB: HELA Cell Lysate 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails

GORAB Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Golgin, RAB6-Interacting Anticorps mieux référencés

  1. Human Polyclonal GORAB Primary Antibody pour IF, WB - ABIN530102 : Hu, Liu, Chen, Chan, Wang, Huo, Zheng, Xie, Guan: SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma. dans Carcinogenesis 2012 (PubMed)

  2. Human Polyclonal GORAB Primary Antibody pour ICC, IF - ABIN4352325 : Egerer, Emmerich, Fischer-Zirnsak, Chan, Meierhofer, Tuysuz, Marschner, Sauer, Barr, Mundlos, Kornak: GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting. dans The Journal of investigative dermatology 2015 (PubMed)

Plus d’anticorps contre Golgin, RAB6-Interacting partenaires d’interaction

Human Golgin, RAB6-Interacting (GORAB) interaction partners

  1. Novel compound heterozygous nonsense mutations were identified in the GORAB gene of a geroderma osteodysplastica patient.

  2. in the present study a de novo deletion on 1q23.3-q24.2 combined with a GORAB missense mutation leads to a distinctive phenotype with features from Gerodermia osteodysplastica and also short stature, cutis laxa, frequent fractures, facial dysmorphism, cup-shaped ears and intellectual disability

  3. SCYL1- BP1 affects the cell cycle through increasing steady state levels of Cyclin F (Montrer CCNF Anticorps) and RRM2 (Montrer RRM2 Anticorps) proteins, thus constituting a dual regulatory circuit

  4. rs17684886 (ZNRF1 (Montrer ZNRF1 Anticorps)) and rs599019 (COLEC12 (Montrer COLEC12 Anticorps)) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5 (Montrer API5 Anticorps)) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes

  5. SCYL1-BP1 plays a critical role in the regulation of EEA1 (Montrer EEA1 Anticorps), BMPR2 (Montrer BMPR2 Anticorps) and BRCA2 (Montrer BRCA2 Anticorps) expression.

  6. SCYL1BP1 can promote the degradation of MDM2 (Montrer MDM2 Anticorps) protein and further inhibit the G1/S transition of lung SCC (Montrer CYP11A1 Anticorps) lines. Reintroduction of SCYL1BP1 into lung SCC (Montrer CYP11A1 Anticorps) lines significantly inhibited cell proliferation, migration, invasion and tumor formation.

  7. Data suggest that SCYL1-BP1 is a novel regulator of the MDM2 (Montrer MDM2 Anticorps)-p53 (Montrer TP53 Anticorps) feedback loop and that it may be a potential tumor suppressor.

  8. The chemotaxis signal pathway induced by chemokines CKbeta8 (Montrer CCL23 Anticorps) and CKbeta8 (Montrer CCL23 Anticorps)-1 is mediated via the Gi/Go protein, phospholipase C (PLC (Montrer PLC Anticorps)) and protein kinase C delta (PKC delta (Montrer PKCd Anticorps)).

  9. study supplements the limited available data on SCYL1BP1 and further establishes deficiency of this recently described golgin as the only known cause of geroderma osteodysplastica

  10. assessment of interaction with hPirh2 (Montrer RCHY1 Anticorps)

Mouse (Murine) Golgin, RAB6-Interacting (GORAB) interaction partners

  1. Gorab role in the abnormal osteoblast differentiation in the gerodermia osteodysplastica

  2. The G59S mutation in p150(glued (Montrer DCTN1 Anticorps)) protein abrogates the normal function of the protein and accelerates motor neuron degeneration (Montrer CLN8 Anticorps).

Golgin, RAB6-Interacting (GORAB) profil antigène

Profil protéine

This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with GORAB

  • golgin, RAB6 interacting (GORAB) anticorps
  • golgin, RAB6-interacting (Gorab) anticorps
  • AI467484 anticorps
  • GO anticorps
  • NTKL-BP1 anticorps
  • NTKLBP1 anticorps
  • Scyl1bp1 anticorps

Protein level used designations for GORAB

N-terminal kinase-like-binding protein 1 , NTKL-binding protein 1 , RAB6-interacting golgin , SCY1-like 1 binding protein 1 , SCY1-like 1-binding protein 1 , SCYL1-BP1 , SCYL1-binding protein 1 , hNTKL-BP1 , dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued , mNTKL-BP1 , NTKL-BP1

GENE ID SPECIES
92344 Homo sapiens
98376 Mus musculus
304923 Rattus norvegicus
770613 Gallus gallus
490349 Canis lupus familiaris
614920 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-Golgin, RAB6-Interacting (GORAB) Anticorps
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