anti-Golgin, RAB6-Interacting (GORAB) Anticorps

GORAB encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. De plus, nous expédions Golgin, RAB6-Interacting Kits (7) et Golgin, RAB6-Interacting Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GORAB 92344 Q5T7V8
GORAB 98376 Q8BRM2
GORAB 304923 B1H222
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Top anti-Golgin, RAB6-Interacting Anticorps sur anticorps-enligne.fr

Showing 10 out of 82 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of GORAB Antibody (N-term) in CHO cell line lysates (35µg/lane). GORAB (arrow) was detected using the purified Pab. Western blot analysis of GORAB Antibody (N-term) in mouse NIH-3T3 cell line lysates (35µg/lane). GORAB (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Souris Inconjugué FACS, IF, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Souris Inconjugué FACS, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Souris Inconjugué WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Lapin Inconjugué WB Western blot analysis of GORAB Antibody (N-term) (ABIN653169) in CHO cell line lysates (35 µg/lane). GORAB (arrow) was detected using the purified polyclonal antibody. Western blot analysis of GORAB Antibody (N-term) (ABIN653169) in mouse NIH-3T3 cell line lysates (35 µg/lane). GORAB (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC (p), WB Immunohistochemistry with NTKLBP1 Polyclonal Antibody 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$456.50
Détails

anti-Golgin, RAB6-Interacting Anticorps mieux référencés

  1. Human Polyclonal GORAB Primary Antibody pour IF, WB - ABIN530102 : Hu, Liu, Chen, Chan, Wang, Huo, Zheng, Xie, Guan: SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma. dans Carcinogenesis 2012 (PubMed)

  2. Human Polyclonal GORAB Primary Antibody pour ICC, IF - ABIN4352325 : Egerer, Emmerich, Fischer-Zirnsak, Chan, Meierhofer, Tuysuz, Marschner, Sauer, Barr, Mundlos, Kornak: GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting. dans The Journal of investigative dermatology 2015 (PubMed)

Plus d’anticorps contre Golgin, RAB6-Interacting partenaires d’interaction

Human Golgin, RAB6-Interacting (GORAB) interaction partners

  1. Loss of RAB6-interacting golgin (GORAB) causes impairment of coat protein complex I (COPI)-mediated retrieval of trans-Golgi enzymes, resulting in a deficit in glycosylation of secretory cargo proteins.

  2. Novel compound heterozygous nonsense mutations were identified in the GORAB gene of a geroderma osteodysplastica patient.

  3. in the present study a de novo deletion on 1q23.3-q24.2 combined with a GORAB missense mutation leads to a distinctive phenotype with features from Gerodermia osteodysplastica and also short stature, cutis laxa, frequent fractures, facial dysmorphism, cup-shaped ears and intellectual disability

  4. SCYL1- BP1 affects the cell cycle through increasing steady state levels of Cyclin F and RRM2 proteins, thus constituting a dual regulatory circuit

  5. rs17684886 (ZNRF1) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes

  6. SCYL1-BP1 plays a critical role in the regulation of EEA1, BMPR2 and BRCA2 expression.

  7. SCYL1BP1 can promote the degradation of MDM2 protein and further inhibit the G1/S transition of lung SCC lines. Reintroduction of SCYL1BP1 into lung SCC lines significantly inhibited cell proliferation, migration, invasion and tumor formation.

  8. Data suggest that SCYL1-BP1 is a novel regulator of the MDM2-p53 feedback loop and that it may be a potential tumor suppressor.

  9. The chemotaxis signal pathway induced by chemokines CKbeta8 and CKbeta8-1 is mediated via the Gi/Go protein, phospholipase C (PLC) and protein kinase C delta (PKC delta).

  10. study supplements the limited available data on SCYL1BP1 and further establishes deficiency of this recently described golgin as the only known cause of geroderma osteodysplastica

  11. assessment of interaction with hPirh2

  12. Study demonstrates that gerodermia osteodysplastica is caused by loss-of-function mutations in SCYL1BP1, which is highly expressed in skin and osteoblasts.

Mouse (Murine) Golgin, RAB6-Interacting (GORAB) interaction partners

  1. Gorab role in the abnormal osteoblast differentiation in the gerodermia osteodysplastica

  2. The G59S mutation in p150(glued) protein abrogates the normal function of the protein and accelerates motor neuron degeneration.

Golgin, RAB6-Interacting (GORAB) profil antigène

Profil protéine

This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with GORAB

  • golgin, RAB6 interacting (GORAB) anticorps
  • golgin, RAB6-interacting (Gorab) anticorps
  • AI467484 anticorps
  • GO anticorps
  • NTKL-BP1 anticorps
  • NTKLBP1 anticorps
  • Scyl1bp1 anticorps

Protein level used designations for GORAB

N-terminal kinase-like-binding protein 1 , NTKL-binding protein 1 , RAB6-interacting golgin , SCY1-like 1 binding protein 1 , SCY1-like 1-binding protein 1 , SCYL1-BP1 , SCYL1-binding protein 1 , hNTKL-BP1 , dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued , mNTKL-BP1 , NTKL-BP1

GENE ID SPECIES
92344 Homo sapiens
98376 Mus musculus
304923 Rattus norvegicus
770613 Gallus gallus
490349 Canis lupus familiaris
614920 Bos taurus
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