anti-Granzyme B (GZMB) Anticorps

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. De plus, nous expédions Granzyme B Kits (82) et Granzyme B Protéines (38) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GZMB 3002 P10144
GZMB    
GZMB    
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Top anti-Granzyme B Anticorps sur anticorps-enligne.fr

Showing 10 out of 290 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Western Blot: Granzyme B Antibody (B18.1) [NBP1-97525] - Detection of recombinant granzyme B. Granzyme B migrates as a 27 kDa species. Method: Recombinant granzyme B was resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and probed with the monoclonal anti-granzyme B antibody B18.1 at 1ug/ml. Proteins were visualized using a peroxidase-conjugated antibody to mouse IgG (SBA) and a chemiluminescence detection system Flow Cytometry: Granzyme B Antibody (B18.1) [NBP1-97525] - Granzyme B Antibody (B18.1) [FITC] Detection of granzyme B in permeabilized human CD8+ T lymphocytes (filled profile). Isotype control in combination with a secondary FITC-labeled antibody is shown as control. Method: Permeabilized human T cells (5 x 10^5 0.1 mg Connectez-vous pour afficher 8 to 11 Days
€432.50
Détails
Chimpanzé Souris Inconjugué EIA, FACS, IHC (fro), IF, IP   0.1 mg Connectez-vous pour afficher 6 to 8 Days
€452.65
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB ABIN6266555 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis on NIH-3T3 cell lysate using Granzyme B Antibody,The lane on the left is treated with the antigen-specific peptide. 100 μL Connectez-vous pour afficher 11 to 12 Days
€345.81
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of GZMB Antibody (C-term) in HL-60 cell line lysates (35 µg/lane). GZMB (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
€345.58
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of GZMB antibody (N-term) in mouse stomach lysates (35 µg/lane). GZMB (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
€345.58
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using Granzyme B Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Granzyme B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
€267.70
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of GZMB antibody (N-term) (ABIN390495) in mouse stomach lysates (35 µg/lane). GZMB (arrow) was detected using the purified polyclonal antibody. GZMB Antibody (N-term) (ABIN390495) IHC analysis in formalin fixed and paraffin embedded human Lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
€340.71
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of GZMB Antibody (C-term) (ABIN390496) in HL-60 cell line lysates (35 µg/lane). GZMB (arrow) was detected using the purified polyclonal antibody. GZMB Antibody (C-term) (ABIN390496) IHC analysis in formalin fixed and paraffin embedded human Lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
€340.71
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Thymus Tissue; Lane2: Mouse Lymph Node Tissue. 100 μg Connectez-vous pour afficher 13 to 16 Days
€279.65
Détails
Humain Souris Inconjugué IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
€462.39
Détails

anti-Granzyme B Anticorps mieux référencés

  1. Human Monoclonal GZMB Primary Antibody pour FACS, ICC - ABIN4316065 : Dressel, Raja, Höning, Seidler, Froelich, von Figura, Günther: Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 8 Pubmed References

  2. Human Monoclonal GZMB Primary Antibody pour FACS - ABIN4896044 : Dorneles, Lima, Teixeira-Carvalho, Araújo, Martins-Filho, Sriranganathan, Al Qublan, Heinemann, Lage: Immune Response of Calves Vaccinated with Brucella abortus S19 or RB51 and Revaccinated with RB51. dans PLoS ONE 2015 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal GZMB Primary Antibody pour FACS - ABIN1302451 : Tak, Spaeny-Dekking, Kraan, Breedveld, Froelich, Hack: The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA). dans Clinical and experimental immunology 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal GZMB Primary Antibody pour FACS - ABIN4896043 : Kreft, Verbraak, Wierenga-Wolf, van Meurs, Oostra, Laman, Hintzen: The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis. dans Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  5. Human Polyclonal GZMB Primary Antibody pour FACS, WB - ABIN4899391 : Jiang, Canfield, Gallagher, Jiang, Jiang, Zheng, Chess: HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes. dans The Journal of clinical investigation 2010 (PubMed)

  6. Human Monoclonal GZMB Primary Antibody pour FACS, IF - ABIN284448 : Marcet-Palacios, Odemuyiwa, Coughlin, Garofoli, Ewen, Davidson, Ghaffari, Kane, Lacy, Logan, Befus, Bleackley, Moqbel: Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. dans Biochemical and biophysical research communications 2008 (PubMed)

  7. Human Monoclonal GZMB Primary Antibody pour IHC (p), WB - ABIN2473886 : Kummer, Kamp, van Katwijk, Brakenhoff, Radosevi?, van Leeuwen, Borst, Verweij, Hack: Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins. dans Journal of immunological methods 1993 (PubMed)
    Show all 2 Pubmed References

  8. Chimpanzee Monoclonal GZMB Primary Antibody pour IHC (fro), FACS - ABIN2473884 : Hsi, Yeh: Monoclonal antibodies to human amnion. dans Journal of reproductive immunology 1987 (PubMed)
    Show all 4 Pubmed References

  9. Human Polyclonal GZMB Primary Antibody pour ICC, IF - ABIN4316064 : Chen, Chen, Choi, Sang, Chen, Zhang, Gouw, Andtbacka, Chan, Rodesch, Jimenez, Cano, Jones, Oyedeji, Martins, Hill, Schumacher, Willmore, Scaife, Ward, Morton, Randall, Lazar, Patel, Trent, Frazier et al.: Exploiting antitumor immunity to overcome relapse and improve remission duration. ... dans Cancer immunology, immunotherapy : CII 2012 (PubMed)

  10. Human Polyclonal GZMB Primary Antibody pour IF (p), IHC (p) - ABIN675354 : Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive. dans Journal of Alzheimer's disease : JAD 2014 (PubMed)

Plus d’anticorps contre Granzyme B partenaires d’interaction

Human Granzyme B (GZMB) interaction partners

  1. our exploratory study suggests that EOMES, BCL6 and GZMB gene expression are aberrant within the PB T cell transcriptome of HT patients. The association of this transcription signature with the heterogeneity of HT and disease control is suggested.

  2. Serum interleukin 1 receptor antagonist (IL1RA) and granzyme B (GZMB) levels were markedly increased in Crohn's disease (CD) patients, suggesting that these markers can serve as biomarkers to identify gut inflammation.

  3. Authors found that R(48)-GzmB is a stable protein that accumulates to similar levels in activated NK cells as Q(48)-GzmB. rs8192917 polymorphism may influence antitumor activity and the effect of antitumor cellular immunotherapy.

  4. GzmA and gzmB were predominantly expressed by natural killer cells, and during abdominal sepsis, the percentage of these cells expressing gzms in peritoneal lavage fluid decreased, while the amount of expression in the gzm(+) cells increased

  5. Study provides evidence that Il10 expression is limited to migratory CD25++ regulatory T cells only.

  6. Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up

  7. Granzyme B breaches the inner membrane through Tim22, the metabolite carrier translocase pore, in a mitochondrial heat-shock protein 70-dependent manner.

  8. Differential proteomics were used to identify granzyme B substrates in three unrelated bacteria: Escherichia coli, Listeria monocytogenes, and Mycobacteria tuberculosis. Granzyme B cleaves a highly conserved set of proteins in all three bacteria, which function in vital biosynthetic and metabolic pathways that are critical for bacterial survival under diverse environmental conditions.

  9. Proteolysis by granzyme B enhances presentation of autoantigenic PAD4 epitopes in rheumatoid arthritis.

  10. our results suggest granzyme B PET imaging can serve as a quantitatively useful predictive biomarker for efficacious responses to cancer immunotherapy.

  11. Plasma GzmB levels may reflect the degree of pruritus and dermatitis in patients with atopic dermatitis

  12. These results suggest the critical importance of miR-378 in the regulation of GrzB expression and a protective role for GrzB in controlling dengue virus replication in vivo.

  13. Analysis of infiltrating granzyme B-expressing T cells at the invasive borders of the colon tumors revealed a significant difference in expression granzyme by race underlining decreased antitumor cytotoxic immunity in African Americans.

  14. Increased TIM3+CD8+T cells with lower perforin and granzyme B expression and higher CD95 expression in MDS patients were observed.

  15. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  16. granzyme-B levels were found to be significantly associated with increased insulin resistance in adolescent polycystic ovary syndrome patients. Additionally, elevated levels of serum granzyme-B were predictive for increased cardiovascular risk in PCOS patients

  17. results suggest that enhanced IL-21R expression of CD19(+)CD5(+) B cells and production of IL-21 by iNKT cells may play an important role in the pathogenesis of pSS by regulating CD19(+)CD5(+) B cell functions and increasing GrB production, presumably leading to a counter-regulatory effect in the disease.

  18. Findings show that GrB was produced in 57.1% colorectal cancer cell (CRC) lines and 100% CRC-derived Cancer Stem Cells and present a novel role for GrB as up-modulator of epitelial-to-mesenchimal transition in CRC cells.

  19. FASL, granzyme B, and cytochrome c blood expression reflects breast cancer progression and response to therapy. (Review)

  20. Data show that NK cell lines could secreted rapidly inactive Mr 35 000 granzyme B (GZB)outside secretory lysosomes (SLs).

Granzyme B (GZMB) profil antigène

Profil protéine

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Gene names and symbols associated with anti-Granzyme B (GZMB) Anticorps

  • granzyme B (GZMB) anticorps
  • CCPI anticorps
  • CGL-1 anticorps
  • CGL1 anticorps
  • CSP-B anticorps
  • CSPB anticorps
  • CTLA1 anticorps
  • CTSGL1 anticorps
  • HLP anticorps
  • SECT anticorps

Protein level used designations for anti-Granzyme B (GZMB) Anticorps

C11 , CTLA-1 , T-cell serine protease 1-3E , cathepsin G-like 1 , cytotoxic T-lymphocyte proteinase 2 , cytotoxic serine protease B , fragmentin 2 , fragmentin-2 , granzyme B , human lymphocyte protein

GENE ID SPECIES
3002 Homo sapiens
Fournisseurs de qualité sélectionnés pour anti-Granzyme B (GZMB) Anticorps