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The protein encoded by GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. De plus, nous expédions GDF5 Anticorps (141) et GDF5 Protéines (37) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 68 products:
Mouse (Murine) GDF5 Kit ELISA pour Sandwich ELISA - ABIN425323
Bae, Ohe, Lee, Heo, Byun, Bae, Kwon, Kwon: Photo-cured hyaluronic acid-based hydrogels containing growth and differentiation factor 5 (GDF-5) for bone tissue regeneration. dans Bone 2013
Show all 2 Pubmed References
Human GDF5 Kit ELISA pour Sandwich ELISA - ABIN417836
Bae, Kim, Lee, Heo, Yang, Kim, Kwon, Bang, Bae, Kwon: ZrO? surface chemically coated with hyaluronic acid hydrogel loading GDF-5 for osteogenesis in dentistry. dans Carbohydrate polymers 2012
Mouse (Murine) GDF5 Kit ELISA pour Sandwich ELISA - ABIN815322
Shtaif, Dror, Bar-Maisels, Phillip, Gat-Yablonski: Growth without growth hormone: can growth and differentiation factor 5 be the mediator? dans Growth factors (Chur, Switzerland) 2015
Changes in the expression of downstream regulators of skeletal differentiation, like barx1 (Montrer BARX1 Kits ELISA) and gdf5, is one mechanism by which head skeletal element number and articulation are altered during evolution.
Results suggest that CDMP1/GDF5 requires cleavage by two distinct proteolytic enzymes.
BMP-14 rs143383 polymorphism reduced the susceptibility to knee osteoarthritis (OA) and hand OA not only in total analysis but also in subgroup analysis; BMP-14 rs143383 polymorphism may be a protective factor against OA occurrence
The structure of Grem2 (Montrer GREM2 Kits ELISA)-GDF5 complex has revealed a number of key findings for DAN-family mediated BMP2 (Montrer BMP2 Kits ELISA) inhibition.
miR (Montrer MLXIP Kits ELISA)-615-3p negatively regulates the osteogenic differentiation of hLF (Montrer EPAS1 Kits ELISA) cells through post-transcriptionally suppressing osteogenic regulators GDF5 and FOXO1 (Montrer FOXO1 Kits ELISA).
p38 (Montrer CRK Kits ELISA), c-jun (Montrer JUN Kits ELISA), and NFkappaB (Montrer NFKB1 Kits ELISA) pathways activated during intervertebral disc degeneration by IL-1beta (Montrer IL1B Kits ELISA) but not GDF-5
GDF5 elicited significant (p < 0.05) changes in the expression of anabolic, catabolic and hypertrophic genes with several consistent effects in healthy donors and in OA patients
GDF5 was up regulated in patients after chronic rhinosinusitis developing osteitis.
he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population
The purpose of this study is to investigate the immunohistochemical expression of cytokeratin 18 (CK18 (Montrer KRT18 Kits ELISA)) and the reactivity to GDF5 (CDMP-1), called the morphogenetic protein-1, cartilage-derived, in lingual squamous cell carcinoma.
homozygous sequence variants in the GDF5 gene underlie acromesomelic dysplasia type-grebe in consanguineous families
The prevention of IL-1Beta (Montrer IL1B Kits ELISA)-induced nucleus pulposus extracellular matrix degeneration by miR-7 (Montrer LILRB1 Kits ELISA) silencing was attenuated by GDF5 siRNA.
spatiotemporal dynamics of Gdf5 expression may instruct lineage divergence.
Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2 (Montrer BMP2 Kits ELISA)-induced Smad1 (Montrer SMAD1 Kits ELISA)-Smad5 (Montrer SMAD5 Kits ELISA)-Smad8 (Montrer SMAD9 Kits ELISA) phosphorylation.
Combined, these data suggest a possible pathway linking GDF5, ERG (Montrer ERG Kits ELISA) and downstream factors in the processes of chondrocyte differentiation during articular joint formation.
Growth differentiation factor 5 is a novel target-derived factor that promotes sympathetic axon growth and branching and makes a distinctive regional contribution to the establishment of sympathetic innervation.
Dach2 (Montrer DACH2 Kits ELISA) and Hdac9 (Montrer HDAC9 Kits ELISA) mediate the effects of muscle activity on muscle reinnervation; Myog (Montrer MYOG Kits ELISA) and Gdf5 appear to stimulate muscle reinnervation through parallel pathways
Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 (Montrer BMP7 Kits ELISA) induced the expression of the alphaV sub-unit.
Clonal expansion of Gdf5 progenitors contributes to linear growth of the enthesis.
GDF5 might play a critical role in 3T3-L1 preadipocyte differentiation
These results suggest that PI3K/Akt (Montrer AKT1 Kits ELISA) signals play a role in the GDF5-mediated brown adipogenesis through a mechanism related to activation of the Smad (Montrer SMAD1 Kits ELISA) pathway.
These results suggest that the SNP of the GDF5 gene could be a very useful genetic marker for body measurement traits in the bovine reproduction and breeding.
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
growth factor GDF5
, growth differentiation factor 5
, growth/differentiation factor 5-like
, cartilage-derived morphogenetic protein-1
, growth/differentiation factor 5
, cartilage-derived morphogenetic protein 1
, growth differentiation factor 5 preproprotein
, growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)