Growth Factor Receptor-Bound Protein 14 (GRB14) Kits ELISA

The product of GRB14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. De plus, nous expédions GRB14 Anticorps (55) et GRB14 Protéines (11) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
GRB14 50915 Q9JLM9
GRB14 58844 O88900
GRB14 2888 Q14449
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Top GRB14 Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 31 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Rat 0.094 ng/mL 0.156-10 ng/mL Diagramm of the ELISA kit to detect Rat GRB14with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Connectez-vous pour afficher 12 to 14 Days
$638.00
Détails
Souris 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$630.00
Détails
Humain 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$630.00
Détails
Poulet 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Cobaye 0.188 ng/mL 0.313-20 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Lapin 0.938 ng/mL 1.563-100 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Mouton
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Chien
  96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails

Plus Kits ELISA pour GRB14 partenaires d'interaction

Mouse (Murine) Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. Study reveals that Grb14 acts as a new signaling node that regulates lipogenesis and modulates insulin sensitivity in the liver by acting at a crossroad between the insulin receptor and the p62-Nrf2-LXR signaling pathways.

  2. The phosphorylation status of the BPS region of Grb14 determines the positive or negative role it will play in insulin receptor (Montrer INSR Kits ELISA) signaling.

  3. Data show that Grb14 inhibits the activity of PTP1B (Montrer PTPN1 Kits ELISA) in retina in a phosphorylation-regulated (Montrer PHAX Kits ELISA) manner, and that rhodopsin (Montrer RHO Kits ELISA)-regulated Src kinase (Montrer CSK Kits ELISA) activation in retina leads to the phosphorylation of Grb14.

  4. Grb14 is a normal physiological modulator of CNG channel function in vivo.

  5. Grb14 functions in vivo as a tissue-specific modulator of insulin (Montrer INS Kits ELISA) action, most likely via repression of IR-mediated IRS-1 (Montrer IRS1 Kits ELISA) tyrosine phosphorylation

  6. regulation of Grb14 expression in adipose tissue may play a physiological role in insulin (Montrer INS Kits ELISA) sensitivity

  7. Grb14 exerts a dual role on the regulation by insulin (Montrer INS Kits ELISA) of hepatic metabolism. It inhibits insulin receptor (Montrer INSR Kits ELISA) catalytic activity, and as a sterol regulatory element binding protein (Montrer CNBP Kits ELISA)-1c maturation.

  8. These results demonstrate that Grb14 can undergo subcellular redistribution upon illumination and suggest that rhodopsin photoexcitation may trigger signaling events alternative to the classical transducin activation.

  9. Grb10 (Montrer GRB10 Kits ELISA) and Grb14 have roles in regulation of insulin (Montrer INS Kits ELISA) signaling and glucose homeostasis

Human Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. We investigated the modification of air pollution and diabetes association by a genetic risk score covering 63 T2D genes. Five single variants near GRB14, UBE2E2, PTPRD, VPS26A and KCNQ1 (Montrer KCNQ1 Kits ELISA) showed nominally significant interactions with PM10 (P<0.05). Our results suggest that genetic risk for T2D may modify susceptibility to air pollution through alterations in insulin (Montrer INS Kits ELISA) sensitivity.

  2. The N-terminus of the BPS domain plays an important role in the regulation of human Grb14 and insulin receptor (Montrer INSR Kits ELISA) complex formation through phosphorylation, in addition to other domains.

  3. Data suggest that GRB10 (Montrer GRB10 Kits ELISA) and GRB14 are both Ca2 (Montrer CA2 Kits ELISA)+-dependent CaM-binding proteins; more than one CaM-binding site and/or accessory CaM-binding sites appear to exist in GRB10 (Montrer GRB10 Kits ELISA) and GRB14, as compared to a single one present in GRB7 (Montrer GRB7 Kits ELISA). (GRB10 (Montrer GRB10 Kits ELISA) = growth factor receptor-bound protein 10 (Montrer GRB10 Kits ELISA); GRB14 = growth factor receptor-bound protein 14; CaM = calmodulin; GRB7 (Montrer GRB7 Kits ELISA) = growth factor receptor-bound protein 7 (Montrer GRB7 Kits ELISA))

  4. Colorectal cancer patients with high GRB14 levels had a shorter survival and GRB14 was upregulated at an advanced clinical stage with enhanced tumor invasion and lymph node metastasis.

  5. Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor (Montrer INSR Kits ELISA).

  6. Genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. Adipose tissue (AT) mRNA expression of 6 genes (TBX15/WARS2, STAB1 (Montrer STAB1 Kits ELISA), PIGC, ZNRF3, GRB14

  7. Modulation of mouse rod photoreceptor responses by Grb14 protein.

  8. ANKRD55 rs459193 and GRB14 rs13389219 associate with insulin (Montrer INS Kits ELISA) resistance.

  9. Studies indicate that insulin receptor (IR (Montrer INSR Kits ELISA)) and IGF Type 1 Receptor (IGFR) have been identified as important partners of Grb10 (Montrer GRB10 Kits ELISA)/14 and SH2B1 (Montrer SH2B1 Kits ELISA)/B2 adaptors.

  10. Grb14 is the first negative regulator of CEACAM3 (Montrer CEACAM3 Kits ELISA)-initiated bacterial phagocytosis and might help to focus granulocyte responses to the subcellular sites of pathogen-host cell contact

Cow (Bovine) Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. These findings suggest that Grb14 may play a regulatory role in granulosa cells during follicular deviation in cattle.

  2. The growth factor receptor (Montrer RYK Kits ELISA) bound protein (Grb) 14 NPXY motif could be acting as a dominant negative for insulin receptor (Montrer INSR Kits ELISA) substrate (IRS)-1 (Montrer IRS1 Kits ELISA) functions in the retina.

  3. Grb14 contains a phosphorylated insulin receptor interacting domain between the pleckstrin homolog) and SH2 domains that binds to and forms a specific complex with the cytoplasmic domain of IRbeta

GRB14 profil antigène

Antigen Summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.

Gene names and symbols associated with GRB14

  • growth factor receptor bound protein 14 (GRB14) anticorps
  • growth factor receptor bound protein 14 (grb14) anticorps
  • growth factor receptor bound protein 14 (Grb14) anticorps
  • AI505286 anticorps
  • GRB14 anticorps

Protein level used designations for GRB14

growth factor receptor-bound protein 14 , growth factor receptor-bound protein 14-like , GRB14 adapter protein , growth factor receptor bound protein 14

GENE ID SPECIES
459695 Pan troglodytes
100390507 Callithrix jacchus
100447515 Pongo abelii
100561062 Anolis carolinensis
50915 Mus musculus
58844 Rattus norvegicus
2888 Homo sapiens
100718629 Cavia porcellus
100514075 Sus scrofa
497029 Bos taurus
100861137 Capra hircus
424183 Gallus gallus
101105217 Ovis aries
100341938 Oryctolagus cuniculus
478770 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour GRB14 (GRB14) Kits ELISA
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