anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) Anticorps

The protein encoded by E2IG3 may interact with p53 and may be involved in tumorigenesis. De plus, nous expédions Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Protéines (6) et Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
E2IG3 26354 Q9BVP2
E2IG3 30877 Q8CI11
E2IG3 290556 Q811S9
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Top anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Anticorps sur anticorps-enligne.fr

Showing 10 out of 139 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué BI, IHC (f), IF, ICS, WB   0.1 mg Connectez-vous pour afficher 6 to 8 Days
$243.52
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-GNL3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysate GNL3 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Mouse Target Name: GNL3 Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml WB Suggested Anti-GNL3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Stomach 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, WB Western Blot: Nucleostemin Antibody [NBP2-42528] - Analysis of HeLa (A )HepG2 (B) and K562 (C) nuclear lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Humain Lapin Inconjugué IHC (p), IP, IHC, WB Detection of Human and Mouse GNL3 by Western Blot (H & M) and Immunoprecipitatation (H). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse 3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-GNL3 antibody ABIN151112 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B). GNL3 was also immunoprecipitated using rabbit anti-GNL3 antibodies ABIN151113 and another GNL3 Ab. Detection: Chemiluminescence with exposure times of 10 seconds (A and B). Immunohistochemistry-Paraffin: Nucleostemin Antibody [ABIN151112] - Human skin carcinoma. Antibody used at a dilution of 1:200. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué IHC (p), IP, IHC, WB Detection of Human and Mouse GNL3 by Western Blot (H & M) and Immunoprecipitatation (H). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse 3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-GNL3 antibody ABIN151113 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate (B). GNL3 was also immunoprecipitated using rabbit anti-GNL3 antibodies ABIN151112 and another GNL3 Ab. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B). Immunohistochemistry-Paraffin: Nucleostemin Antibody [ABIN151113] - Human skin carcinoma. Antibody used at a dilution of 1:1,000. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Souris Inconjugué FACS, ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of GNL3 Antibody (C-term) (ABIN388154) in HL60 cell line lysates (35 µg/lane). GNL3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GNL3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Souris Inconjugué ELISA, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Humain Lapin Inconjugué WB Western blot analysis of anti-GNL3 Antibody (Center) (ABIN388155) in HL60 cell line lysates (35 µg/lane). GNL3 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails

E2IG3 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Anticorps mieux référencés

  1. Human Monoclonal E2IG3 Primary Antibody pour BI, IHC (f) - ABIN2689866 : Kafienah, Mistry, Williams, Hollander: Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow. dans Stem cells (Dayton, Ohio) 2006 (PubMed)
    Show all 5 Pubmed References

  2. Mouse (Murine) Polyclonal E2IG3 Primary Antibody pour WB - ABIN1881380 : Hirai, Romanova, Kellner, Verma, Rayner, Asakura, Kikyo: Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation. dans Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal E2IG3 Primary Antibody pour IHC (p), IP - ABIN151112 : Okamoto, Yasukawa, Nguyen, Kasim, Maida, Possemato, Shibata, Ligon, Fukami, Hahn, Masutomi: Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. dans Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal E2IG3 Primary Antibody pour ELISA, WB - ABIN1724769 : Meng, Hsu, Tsai: GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest. dans Oncogene 2011 (PubMed)

  5. Human Polyclonal E2IG3 Primary Antibody pour ELISA, WB - ABIN4341079 : Yoshida, Fujimoto, Kudoh, Nagata, Nakayama, Shinohara, Ito: Nucleostemin affects the proliferation but not differentiation of oral squamous cell carcinoma cells. dans Cancer science 2011 (PubMed)

Plus d’anticorps contre Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) partenaires d’interaction

Zebrafish Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. The nucleolar GTP-binding (Montrer RND2 Anticorps) proteins Gnl2 (Montrer GNL2 Anticorps) and nucleostemin are required for retinal neurogenesis in developing zebrafish.

Human Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. In addition, migration and invasion demonstrated significant inhibition in Nucleostemin-deficient cells. Furthermore, the knockdown of Nucleostemin dramatically suppressed xenograft progression in BALB/c nude mice. Our findings suggest that Nucleostemin is associated with malignancy in an ovarian cancer SKOV-3 cell line.

  2. Identified a positive correlation between up-regulation of nucleostemin and human glioma cell proliferation and that knocking-down nucleostemin alleviated glioma proliferation by reducing beta-Catenin (Montrer CTNNB1 Anticorps) transportation into the nucleus.

  3. Relative expression of GNL3 in synovial tissue and fluid samples was significantly higher in the osteoarthritic group as compared to the non-osteoarthritic group.

  4. The expression level of GNL3 was examined in 89 human gastric cancer samples using immunohistochemistry (IHC) staining. GNL3 in gastric cancer tissues was significantly upregulated compared with paracancerous tissues.

  5. over-expression of GNL3 and SKA3 (Montrer SKA3 Anticorps) in the PC-3 (Montrer PCSK1 Anticorps) human prostate cancer cell line decreased in vitro cell migration and invasion

  6. p53 (Montrer TP53 Anticorps) activation by inauhzin via inhibiting SIRT1 (Montrer SIRT1 Anticorps), also inhibits cellular IMPDH2 (Montrer IMPDH2 Anticorps) activity, reduces the levels of cellular GTP (Montrer AK3 Anticorps) and GTP-binding (Montrer RND2 Anticorps) nucleostemin, thus representing in a new anti-cancer strategy.

  7. overexpression of NS suppressed ARF polyubiquitination by its E3 ligase Ubiquitin Ligase for ARF and elongated its half-life, whereas knockdown of NS led to the decrease of ARF levels

  8. Silence of nucleostemin inhibit cell proliferation through up-regulating p21 (Montrer CDKN1A Anticorps) expression and nucleostemin may be involved in the pathogenesis of esophageal squamous cell carcinoma.

  9. It is concluded that nucleostemin expression could not be specific in a certain type of cells in colon cancer cell line HT29.

  10. Data shows that the NS protein expression status was positively correlated with both ER and HER2 (Montrer ERBB2 Anticorps) status and was a powerful prognostic factor.

Mouse (Murine) Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin expression participates in the preservation of the viability and integrity of embryonic stem cells.

  2. nucleostemin protects hematopoietic stem cells (HSCs) from DNA damage accumulation and is required for the maintenance of HSCs.

  3. Mechanistic studies performed in mouse embryonic fibroblast cells showed that loss of nucleostemin triggers DNA damage and growth arrest independently of the p53 (Montrer TP53 Anticorps) status or rRNA synthesis

  4. Nucleostemin in the maintenance of ESC self-renewal, demonstrate the importance of rapid transit through G1 for this process, and expand the known classes of reprogramming factors.

  5. NS functions downstream of Myc (Montrer MYC Anticorps) as a rate-limiting regulator of cell proliferation and transformation.

  6. NS undergoes a ubiquitin- and MDM2 (Montrer MDM2 Anticorps)-independent proteasomal degradation when intracellular GTP (Montrer AK3 Anticorps) levels are markedly reduced

  7. a complex composed of TERT (Montrer TERT Anticorps), BRG1 (Montrer SMARCA4 Anticorps), and NS/GNL3L (Montrer GNL3L Anticorps) maintains the function of tumor initiating cells

  8. Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.

  9. analysis of nucleolar localization of stem cell protein (Montrer TAL1 Anticorps) nucleostemin

  10. Nucleostemin has a unique ability, derived from an ancestral function, to control the proliferation rate of stem/progenitor cells in vivo independently of p53.

Xenopus laevis Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) interaction partners

  1. Nucleostemin functions in early amphibian development to control cell proliferation of neural progenitor cells.

Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (E2IG3) profil antigène

Profil protéine

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with E2IG3

  • guanine nucleotide binding protein-like 3 (nucleolar) (gnl3) anticorps
  • G protein nucleolar 3 (GNL3) anticorps
  • guanine nucleotide binding protein-like 3 (nucleolar) (Gnl3) anticorps
  • G protein nucleolar 3 (Gnl3) anticorps
  • guanine nucleotide binding protein-like 3 (nucleolar) L homeolog (gnl3.L) anticorps
  • BC037996 anticorps
  • C77032 anticorps
  • E2IG3 anticorps
  • id:ibd2914 anticorps
  • NNP47 anticorps
  • Ns anticorps
  • nstm anticorps
  • wu:fb38a04 anticorps
  • wu:fc55d07 anticorps
  • zgc:123093 anticorps

Protein level used designations for E2IG3

guanine nucleotide-binding protein-like 3 , nucleostemin , nucleostemin-like protein , guanine nucleotide binding protein-like 3 (nucleolar) , guanine nucleotide-binding protein-like 3-like , E2-induced gene 3 protein , estradiol-induced nucleotide binding protein , novel nucleolar protein 47 , nucleolar GTP-binding protein 3

GENE ID SPECIES
321897 Danio rerio
394765 Xenopus (Silurana) tropicalis
415897 Gallus gallus
100155235 Sus scrofa
100231668 Taeniopygia guttata
100458988 Pongo abelii
26354 Homo sapiens
30877 Mus musculus
100685258 Canis lupus familiaris
506152 Bos taurus
290556 Rattus norvegicus
380340 Xenopus laevis
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