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HSPA1L encodes a 70kDa heat shock protein. De plus, nous expédions Heat Shock 70kDa Protein 1-Like Kits (15) et Heat Shock 70kDa Protein 1-Like Protéines (12) et beaucoup plus de produits pour cette protéine.
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HSP70-HOM gene polymorphism associated with susceptibility to noise-induced hearing loss.
This is the first study to show that HSPA1L mediated HIF-1alpha (Montrer HIF1A Anticorps) stabilization. In addition, this is the first study to show that GP78 (Montrer AMFR Anticorps) inactivation promotes cancer cell proliferation, migration and eventual tumor growth both in vivo and in vitro by increasing cellular prion protein (Montrer PRNP Anticorps).
In a cohort of youth at risk for bipolar disorder, pathway analysis showed an enrichment of the glucocorticoid receptor (GR (Montrer NR3C1 Anticorps)) pathway with the genes MED1 (Montrer MED1 Anticorps), HSPA1L, GTF2A1 (Montrer GTF2A1 Anticorps) and TAF15 (Montrer TAF15 Anticorps), which might underlie the previously reported role of stress response in the risk for bipolar disorder in vulnerable populations.
The rs2763979 locus of the HSP70 (Montrer HSP70 Anticorps) genes may be associated with susceptibility to noise-induced hearing loss (NIHL) in Chinese individuals, and other HSP70 (Montrer HSP70 Anticorps) genes may also be susceptibility genes for NIHL, but the results must be further replicated in additional independent sample sets.
A heterozygous de novo mutation (c.830C > T; p.Ser277Leu) in HSPA1L in ulcerative colitis patient. Five additional rare HSPA1L mutations (p.Gly77Ser, p.Leu172del, p.Thr267Ile, p.Ala268Thr, p.Glu558Asp) were found in six other patients. All six rare HSPA1L variant proteins showed decreased chaperone activity in vitro. Moreover, three variants demonstrated dominant negative effects on HSPA1L and HSPA1A (Montrer HSPA1A Anticorps) protein activity.
Polymorphism of HSPA1L gene is associated with the development of esophageal Carcinoma.
HSPA1L (rs2227956) is associated with a decreased risk of idiopathic pulmonary fibrosis in a Mexican population.
HSP70-hom polymorphisms modify the association of diethylhexyl phthalates exposure with insulin (Montrer INS Anticorps) resistance.
The potential implication of HSPA1A (Montrer HSPA1A Anticorps) +190G/C, HSPA1B (Montrer HSPA1A Anticorps) +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population, was analyzed.
In HSPA1L T2437C polymorphisms, there was no significant differences in frequencies of the variant homozygous in patients compared to controls.
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.
Heat shock 70 kDa protein 1L
, heat shock 70 kDa protein 1-like
, heat shock 70 kDa protein 1L
, heat shock 70 kDa-like protein 1
, heat shock 70kDa protein 1-like
, heat shock protein cognate 70, testis
, heat shock-related protein hsc70t
, inducible heat shock protein 70
, spermatid-specific heat shock protein 70
, heat shock 10kDa protein 1-like
, Heat shock protein 70-1l
, heat shock 70 kDa protein 3
, heat shock 70 kDa protein 1-Hom
, heat shock 70kD protein-like 1
, heat shock 70kDa-like protein 1