anti-Hect Domain and RLD 5 (HERC5) Anticorps

HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. De plus, nous expédions Hect Domain and RLD 5 Protéines (4) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HERC5 51191 Q9UII4
HERC5 514373  
HERC5 100063774  
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Top anti-Hect Domain and RLD 5 Anticorps sur anticorps-enligne.fr

Showing 10 out of 13 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-HERC5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-HERC5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HT1080 cell lysate Rabbit Anti-HERC5 antibody  Formalin Fixed Paraffin Embedded Tissue: Human Testis Primary antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20x Exposure Time: 0.5-2.0sec 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL 11 to 12 Days
$305.71
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Détails
Humain Lapin Inconjugué WB HERC5 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Détails
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
$654.50
Détails

anti-Hect Domain and RLD 5 Anticorps mieux référencés

  1. Human Polyclonal HERC5 Primary Antibody pour ELISA, WB - ABIN565561 : Woods, Kelly, Hattlmann, Tong, Xu, Coleman, Quest, Smiley, Barr: Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. dans Retrovirology 2011 (PubMed)
    Show all 4 Pubmed References

Plus d’anticorps contre Hect Domain and RLD 5 partenaires d’interaction

Human Hect Domain and RLD 5 (HERC5) interaction partners

  1. Low HERC5 expression is associated with HIV infections.

  2. A synonymous mutation at rs6857425 (T-C) was present in the same region among all study groups (T-C), irrespective of their HIV status.

  3. Results show that HERC5 mediates covalent ISG15 conjugation to parkin in mammalian cells and that ISG15 is conjugated to the Lys349 and Lys369 residues of parkin.

  4. HERC5 plays a crucial role in HCC immune evasion and has clinical relevance as a reproducible prognostic marker for risk of tumor recurrence and survival in patients.

  5. The inhibitory effect of ISG15 on HCV RNA replication does not require its conjugation to substrates by HERC5.

  6. vIRF1 association with HERC5 altered ISG15 modification of cellular proteins, and knockdown of ISG15 augmented reactivation of KSHV from latency.

  7. The study reports on the NMR solution structure of a G-quadruplex formed by the CEB1 DNA G-rich fragment d(AGGGGGGAGGGAGGGTGG), harboring several G-tracts including one with six continuous guanines.

  8. Results show that HERC5 gene may be involved in regulating the spread of non-small cell lung cancer tumors where the methylation of its promoter is correlated with number increase of disseminated tumor cells and metastases as well as survival decreased.

  9. Authors identified a second distinct mechanism by which HERC5 inhibits HIV-1 replication and demonstrate that HERC5 is evolving under strong positive selection.

  10. Data indicate that income was inversely related to smoking behavior, and paternally derived CEB1 mutations were dose dependently increased when the father smoked in the 6 mo before pregnancy, 0.21 vs. 0.05 in smoking and nonsmoking fathers, respectively.

  11. The E3 ligase activity of HERC5 was required for blocking HIV-1 Gag particle production and correlated with the post-translational modification of Gag with ISG15.

  12. This study characterizes HERC5 as a positive regulator of innate antiviral responses, and show that it sustains IRF3 activation via a novel posttranslational modification, ISG15-ylation.

  13. Data show that HERC5, a functionally active HECT ubiquitin ligase, exhibits a tightly controlled cytosolic level under inflammatory conditions in endothelial cells.

  14. HERC5/Ceb1 is involved in the conjugation of ISG15 to cellular proteins.

  15. these results suggest that Herc5 functions as a general E3 ligase for protein ISGylation.

  16. Overexpression of cyclin E is associated with neuroendocrine lung tumors

Hect Domain and RLD 5 (HERC5) profil antigène

Profil protéine

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

Gene names and symbols associated with HERC5

  • HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5) anticorps
  • hect domain and RLD 5 (HERC5) anticorps
  • CEB1 anticorps
  • CEBP1 anticorps
  • HERC5 anticorps

Protein level used designations for HERC5

E3 ISG15--protein ligase HERC5 , hect domain and RLD 5 , probable E3 ubiquitin-protein ligase HERC5-like , HECT domain and RCC1-like domain-containing protein 5 , cyclin-E-binding protein 1 , probable E3 ubiquitin-protein ligase HERC5

GENE ID SPECIES
514373 Bos taurus
461369 Pan troglodytes
478474 Canis lupus familiaris
100063774 Equus caballus
100410536 Callithrix jacchus
100438710 Pongo abelii
100480303 Ailuropoda melanoleuca
100584608 Nomascus leucogenys
51191 Homo sapiens
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