anti-Hepatic Leukemia Factor (HLF) Anticorps

HLF encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. De plus, nous expédions HLF Kits (6) et HLF Protéines (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HLF 217082 Q8BW74
HLF 3131 Q16534
HLF 690286  
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Top anti-HLF Anticorps sur anticorps-enligne.fr

Showing 10 out of 46 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-Hlf Antibody Titration: 1.0 ug/ml Positive Control: Mouse Testis 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-HLF Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Hela cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of to HLF on HeLa cell . Western Blot analysis of HLF expression in transfected 293T cell line by HLF monoclonal antibody (M04), clone M2. Lane 1: HLF transfected lysate(33.2 KDa). Lane 2: Non-transfected lysate. 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué WB HLF Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HLF antibody detected the HLF protein (arrow). All lanes : Anti-HLF Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Western blot analysis of HLF using HeLa whole  lysates. ABIN6278024 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of mouse liver and mouse brain cells, using HLF antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.77
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Souris Inconjugué IF, RNAi, ELISA, WB Western Blot analysis of HLF expression in transfected 293T cell line by HLF monoclonal antibody (M04), clone M2.<br><br>Lane 1: HLF transfected lysate(33.2 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of monoclonal antibody to HLF on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Souris Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using HLF antibody (ABIN5971611) at 1/1000 dilution. 100 μL Connectez-vous pour afficher 11 to 16 Days
$412.19
Détails

anti-HLF Anticorps mieux référencés

  1. Human Monoclonal HLF Primary Antibody pour IF, RNAi - ABIN561276 : Murakami, Higashi, Matsunaga, Koyanagi, Ohdo: Circadian clock-controlled intestinal expression of the multidrug-resistance gene mdr1a in mice. dans Gastroenterology 2008 (PubMed)

Plus d’anticorps contre HLF partenaires d’interaction

Mouse (Murine) Hepatic Leukemia Factor (HLF) interaction partners

  1. HLF-deficient hematopoietic stem cells display loss of quiescence and increased sensitivity to chemotoxic insults.

  2. Results demonstrate that Hlf is a genetic modifier of epilepsy caused by voltage-gated sodium channel mutations and that modulation of the pyridoxine pathway can also influence phenotype severity

  3. Conditional expression of E2A (Montrer TCF3 Anticorps)-HLF induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  4. Data indicate that Meis homeobox 1 (MEIS1 (Montrer MEIS1 Anticorps)) is required for the maintenance of myeloid-lymphoid leukemia protein MLL (Montrer MLL Anticorps)-fusion gene leukemia, and hepatic leukemia factor (HLF)is a key downstream mediator of Meis1 (Montrer MEIS1 Anticorps).

  5. we demonstrate that D site albumin promoter binding protein/thyrotroph embryonic factor (Montrer TEF Anticorps)/hepatic leukemia factor triple knockout mice develop cardiac hypertrophy and left ventricular dysfunction associated with a low blood pressure

  6. mice deficient for all three PAR (Montrer AFG3L2 Anticorps) bZip proteins (DBP (Montrer GC Anticorps),HLF,& TEF (Montrer TEF Anticorps)) are highly susceptible to generalized spontaneous and audiogenic epilepsies, frequently lethal. Pyridoxal kinase (Montrer PDXK Anticorps) is a target gene of PAR (Montrer AFG3L2 Anticorps) bZip proteins in both liver and brain

  7. The HLF protein control the expression of many enzymes and regulators involved in detoxification and drug metabolism, such as cytochrome P450 (Montrer CYP Anticorps) enzymes, carboxylesterases, and constitutive androstane receptor (Montrer NR1I3 Anticorps) (CAR).

  8. Data show that the clock knockout mice or mice devoid of dbp (Montrer GC Anticorps)/hlf/tef (Montrer TEF Anticorps) (triple knockout) exhibit significant changes in renal expression of several key regulators of water or sodium balance.

Human Hepatic Leukemia Factor (HLF) interaction partners

  1. Poly (ADP-ribose) polymerase (Montrer PARP1 Anticorps) inhibitors selectively induce cytotoxicity in TCF3 (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps)-positive leukemic cells.

  2. HLF-mediated miR-132 directly suppresses TTK expression, thus exerting inhibitory effects on cancer cell proliferation, metastasis and radioresistance.

  3. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3 (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps) ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids.

  4. ectopic expression of HLF (Montrer EPAS1 Anticorps), an established transcription factor that cycles with circadian rhythms, can recapitulate many features associated with circadian-dependent physiological variation.

  5. both Lmo2 (Montrer LMO2 Anticorps) and Bcl-2 (Montrer BCL2 Anticorps) are required for the action of E2A (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps) in leukemogenesis

  6. E2A (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps) promotes cell survival of t(17;19)- acute lymphoblastic leukemia cells by aberrantly up-regulating LMO2 (Montrer LMO2 Anticorps) expression

  7. Evidence pertaining to leukemogenesis by the well-characterized oncogenic fusion protein E2A (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps) is reviewed and its mechanistic implications are considered.

  8. E2A-HLF induces annexin II by substituting for cytokines that activate downstream pathways of Ras

  9. The E2A (Montrer TCF3 Anticorps)-HLF (Montrer EPAS1 Anticorps)-mediated over-expression of ABCB1 (Montrer ABCB1 Anticorps) may play a role in the clinical phenotype of ALLs with a t(17;19), suggesting pharmacologic modulation of ABCB1 (Montrer ABCB1 Anticorps) activity as a rational therapeutic strategy for this chemotherapy resistant subtype of ALL.

  10. The patients with immunophenotype of Pre-B-acute lymphoblastic leukemia were found to carry: E2A (Montrer TCF3 Anticorps)/PBX1 (Montrer PBX1 Anticorps) and E2A (Montrer TCF3 Anticorps)/HLF (Montrer EPAS1 Anticorps).

HLF profil antigène

Profil protéine

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with HLF

  • HLF, PAR bZIP transcription factor (HLF) anticorps
  • hepatic leukemia factor (Hlf) anticorps
  • hepatic leukemia factor a (hlfa) anticorps
  • Hepatic leukemia factor (Bm1_18395) anticorps
  • Hepatic leukemia factor (hlf) anticorps
  • HLF, PAR bZIP transcription factor (Hlf) anticorps
  • DKFZp469P0721 anticorps
  • E230015K02Rik anticorps
  • Hlf anticorps
  • HLF1 anticorps
  • zgc:153035 anticorps

Protein level used designations for HLF

hepatic leukemia factor , hepatic leukemia factor 1 , zhlf1 , Hepatic leukemia factor

GENE ID SPECIES
706623 Macaca mulatta
516069 Bos taurus
217082 Mus musculus
100192429 Ovis aries
100171535 Pongo abelii
593063 Strongylocentrotus purpuratus
417395 Gallus gallus
455140 Pan troglodytes
3131 Homo sapiens
768192 Danio rerio
6098588 Brugia malayi
100380463 Salmo salar
100724740 Cavia porcellus
690286 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-HLF (HLF) Anticorps
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