Homer Homolog 3 (Drosophila) Protéines (HOMER3)

HOMER3 encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. De plus, nous expédions HOMER3 Anticorps (62) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
HOMER3 9454 Q9NSC5
HOMER3 26558 Q99JP6
Rat HOMER3 HOMER3 29548 Q9Z2X5
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top HOMER3 Protéines sur anticorps-enligne.fr

Showing 5 out of 8 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,370.21
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 11 Days
$888.80
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$400.00
Détails

HOMER3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour Homer Homolog 3 (Drosophila) (HOMER3) partenaires d'interaction

Human Homer Homolog 3 (Drosophila) (HOMER3) interaction partners

  1. Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation.

  2. Interaction of the protein with amyloid precursor protein is regulated by calcium homeostasis.

  3. Loss of Homer3 is associated with acute myeloid leukemia.

  4. Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta subunit of the IKK complex.

  5. Homer-3 may be involved in the regulation of SRE activation in T cells via interaction between its EVH1 domain and C/EBP beta.

  6. Fat1 exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells

  7. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin

Mouse (Murine) Homer Homolog 3 (Drosophila) (HOMER3) interaction partners

  1. impaired mTORC1-Homer-3 activity underlies PC susceptibility in Spinocerebellar ataxia type 1 and presents a promising therapeutic target

  2. Expression of Homer 3a/b is restricted to the developing cerebellum, hippocampus, and neonatal olfactory bulb, and is concentrated in the dendritic spines of Purkinje cells and their axons.

  3. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin

  4. Homer2 and Homer3 proteins interact specifically with amyloid precursor protein (APP) by inhibiting APP processing and reducing secretion of Abeta peptides.

  5. Homer3 in Purkinje cells might function as a reversible coupler regulated by CaMKII phosphorylation and that the phosphorylation is capable of regulating the postsynaptic molecular architecture in response to synaptic activity.

Profil protéine HOMER3

Profil protéine

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with HOMER3

  • homer scaffolding protein 3b (homer3b)
  • homer scaffolding protein 3 (HOMER3)
  • homer scaffolding protein 3 (Homer3)
  • AW146114 Protéine
  • HOMER-3 Protéine
  • Vesl-3 Protéine
  • VESL3 Protéine
  • zgc:55557 Protéine

Protein level used designations for HOMER3

homer protein homolog 3 , Homer, neuronal immediate early gene, 3 , homer homolog 3 (Drosophila) , homer, neuronal immediate early gene, 3 , homer-3 , VASP/Ena-related gene up-regulated during seizure and LTP 3

GENE ID SPECIES
394088 Danio rerio
736171 Pan troglodytes
100605039 Nomascus leucogenys
9454 Homo sapiens
26558 Mus musculus
29548 Rattus norvegicus
420115 Gallus gallus
484813 Canis lupus familiaris
508124 Bos taurus
Fournisseurs de qualité sélectionnés pour HOMER3 Protéines (HOMER3)
Avez-vous cherché autre chose?