anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Anticorps

The protein encoded by HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). De plus, nous expédions HIF3A Kits (7) et HIF3A Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HIF3A 64344 Q9Y2N7
HIF3A 53417 Q0VBL6
HIF3A 64345 Q9JHS2
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Top anti-HIF3A Anticorps sur anticorps-enligne.fr

Showing 10 out of 97 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC, WB WB Suggested Anti-HIF3A Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate There is BioGPS gene expression data showing that HIF3A is expressed in HepG2 Human kidney 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of HIF3 alpha expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ICC, IF, IP, WB Western Blot: HIF-3 alpha Antibody [ABIN250965] - Hif3a expression in papillary renal cell carcinoma samples. Image from verified customer review. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Souris Inconjugué IHC, IHC (p), WB Immunohistochemistry: HIF-3 alpha Antibody (2D2) [NBP2-45735] - Analysis of Carcinoma of Human bladder tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Western Blot: HIF-3 alpha Antibody (2D2) [NBP2-45735] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HIF3A. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$585.06
Détails
Souris Lapin Inconjugué ELISA, WB Western blot using Affinity Purified anti-Hif3A antibody shows detection of a band ~72 kDa corresponding to mouse Hif3A (arrowhead).   Approximately 10 µg of a CoCl<sub>2</sub> treated 3T3 cell lysate (lane 1) and control 3T3 cell lysate (lane 2) were separated by 4-20% SDS-PAGE and transferred onto nitrocellulose.  Treatment of exponentially growing 3T3 cells with 130 µM CoCl<sub>2</sub> for 6 h at 37° C effectively mimics hypoxia.   After blocking the membrane was probed overnight at 4° C with the primary antibody diluted to 1:1,600.  The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-132-122) for 45 min at room temperature. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. Western blot using  Affinity Purified anti-Hif antibody shows detection of a band ~72 kDa corresponding to mouse Hif3a (arrowhead). Approximately 10 ?g of a CoCl2 treated 3T3 cell lysate (lane 1) and control 3T3 cell lysate (lane 2) were separated by 4-20% SDS-PAGE and transferred onto nitrocellulose. Treatment of exponentially growing 3T3 cells with 130 uM CoCl2 for 6 h at 37° C effectively mimics hypoxia. After blocking the membrane was probed overnight at 4° C with the primary antibody diluted to 1:1,600. The membrane was washed and reacted with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX  for 45 min at room temperature. IRDye800 fluorescence image was captured using the Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 100 μg Connectez-vous pour afficher 7 to 9 Days
$389.00
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Souris Inconjugué WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Souris Lapin Inconjugué EIA, IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$619.30
Détails
Humain Lapin Inconjugué WB Detection of HIF-3 alpha in a reticulocyte lysate using ABIN151687. Western Blot: HIF-3 alpha Antibody [ABIN250675] - Analysis of HIF-3 alpha in Jurkat cell lysate. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$415.44
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, IHC (p), WB Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with HIF3A antibody ABIN214599 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Placenta (formalin-fixed, paraffin-embedded) stained with HIF3A antibody ABIN214599 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails

HIF3A Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-HIF3A Anticorps mieux référencés

  1. Human Polyclonal HIF3A Primary Antibody pour ICC, IF - ABIN250964 : Forooghian, Razavi, Timms: Hypoxia-inducible factor expression in human RPE cells. dans The British journal of ophthalmology 2007 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal HIF3A Primary Antibody pour IHC, WB - ABIN2778530 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. dans Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal HIF3A Primary Antibody pour WB - ABIN151687 : Jackson, Zhang, Hadley, Rabbani, Zhang, Marks, Vujaskovic: Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung. dans Free radical biology & medicine 2012 (PubMed)

  4. Human Polyclonal HIF3A Primary Antibody pour ICC, IF - ABIN315681 : Huang, Kapere Ochieng, Kempen, Munck, Swagemakers, van Ijcken, Grosveld, Tibboel, Rottier: Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development. dans PLoS ONE 2013 (PubMed)

  5. Human Monoclonal HIF3A Primary Antibody pour IHC, IHC (p) - ABIN4317485 : Liu, Fang, Song, Jiang, He, Liu: Expression of hypoxia-inducible factor 3α in hepatocellular carcinoma and its association with other hypoxia-inducible factors. dans Experimental and therapeutic medicine 2016 (PubMed)

  6. Mouse (Murine) Polyclonal HIF3A Primary Antibody pour ELISA, WB - ABIN100475 : Takeda, Ho, Takeda, Duan, Nagy, Fong: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. dans Molecular and cellular biology 2006 (PubMed)

Plus d’anticorps contre HIF3A partenaires d’interaction

Human Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

  1. AA can protect cardiomyocytes against hypoxia-induced apoptosis through regulating the miR (Montrer MLXIP Anticorps)-1290/HIF3A/HIF-1alpha (Montrer HIF1A Anticorps) axis, and miR (Montrer MLXIP Anticorps)-1290 may be a potential target in the prevention of myocardial ischemia-reperfusion injury

  2. NAP peptide prevents outer blood retinal barrier breakdown by reducing HIF1alpha (Montrer HIF1A Anticorps)/HIF2alpha (Montrer EPAS1 Anticorps), VEGF (Montrer VEGFA Anticorps)/VEGFRs, and increasing HIF3alpha expression Moreover it is able to reduce the percentage of apoptotic cells by modulating the expression of two death related genes, BAX (Montrer BAX Anticorps) and Bcl2 (Montrer BCL2 Anticorps).

  3. HIF3A methylation was found in the association between the HIF3A rs3826795 polymorphism and alanine aminotransferase (Montrer ALT Anticorps) among obese children.

  4. TIMP2 (Montrer TIMP2 Anticorps) suppression, in a hypoxic environment, was induced through a regulatory feedback circuit consisting of hypoxia-inducible factor (HIF) 1 alpha (Montrer HIF1A Anticorps), microRNA-210 (miR (Montrer MLXIP Anticorps)-210), and HIF-3alpha.

  5. Results were discordant with those expected if HIF3A methylation has a causal effect on body mass index (BMI) & provided more evidence for causality in the reverse direction (i.e., an effect of BMI on HIF3A methylation); results also show a long-lasting intergenerational influence of maternal BMI on offspring methylation at this locus, which may confound associations between own adiposity & HIF3A methylation.

  6. DNA methylation (Montrer HELLS Anticorps) in HIF3A shares moderate correlation between adipose tissue and blood, and both are associated with BMI. In contrast, methylation in FASN (Montrer FASN Anticorps) is poorly correlated across tissues, but the DNA methylation (Montrer HELLS Anticorps) in adipose tissue but not blood is highly associated with BMI

  7. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (Montrer HIF1A Anticorps) or Bcl-xL (Montrer BCL2L1 Anticorps), binding proteins of IPAS in the nucleus and mitochondria, respectively.

  8. Results confirmed a positive association between BMI and HIF3A DNA promoter methylation in the blood. The tissue-specific results of HIF3A gene expression indicate that subcutaneous adipose tissue is the more functional tissue in which a low expression may adversely affect whole-body insulin (Montrer INS Anticorps) sensitivity.

  9. Parkin (Montrer PARK2 Anticorps) is downregulated under hypoxia and that it interferes with HIF expression based on cellular oxygen tension.

  10. This provides a compelling model for how hypoxia-induced miR (Montrer MLXIP Anticorps)-429 regulates the switch between HIF-1 (Montrer HIF1A Anticorps) adaptive responses to HIF-3 survival responses by rapidly decreasing HIF1A (Montrer HIF1A Anticorps) levels while simultaneously slowing the progression of HIF3A expression until the miR (Montrer MLXIP Anticorps)-429 levels drop below normoxic levels.

Mouse (Murine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

  1. Phosphorylation of inhibitory PAS domain protein (IPAS) at Ser184 by MAPK-activated protein kinase 2 (MK2 (Montrer MAPKAPK2 Anticorps) or MAPKAPK2 (Montrer MAPKAPK2 Anticorps)) enhances the proapoptotic function of IPAS.

  2. Report suggests that BV-2 microglial cells express HIF-3a under inflammatory conditions and that its activation differed from that of HIF-1a (Montrer HIF1A Anticorps)

  3. mRNA of HIF-2alpha (Montrer EPAS1 Anticorps) and Ets-1 (Montrer ETS1 Anticorps) were significantly increased by HIF-3alpha ablation. Both factors activate the VE-cadherin (Montrer CDH5 Anticorps) gene, the transcriptional repression of these factors by HIF-3alpha is important for silencing the irrelevant expression of the VE-cadherin (Montrer CDH5 Anticorps) gene.

  4. our data indicated that Tnni2K175del mutation led to abnormally increased hif3a and decreased vegf (Montrer VEGFA Anticorps) in bone, which explain, at least in part, the small body size of Tnni2K175del mice

  5. Anoxia preconditioning increases anti-ischemic neuronal resistance which to a certain extent correlates with the changes of HIF-1alpha (Montrer HIF1A Anticorps) and HIF-3alpha expression.

  6. alternative splicing and expression of IPAS is induced by hypoxia.

  7. By generating mice with a targeted disruption of the NEPAS/HIF-3alpha locus, it was found that homozygous mutant mice, NEPAS/HIF-3alpha(-/-), were viable but displayed enlargement of the right ventricle and impaired lung remodeling.

  8. Identity of third HIF alpha class member, HIF-3alpha. mRNA expression information by mouse MTN. Experimental proof of dimerization with ARNT/HIF-1beta (Montrer ARNT Anticorps).

Zebrafish Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

Cow (Bovine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

HIF3A profil antigène

Profil protéine

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with HIF3A

  • hypoxia inducible factor 3 alpha subunit (HIF3A) anticorps
  • hypoxia inducible factor 3, alpha subunit (Hif3a) anticorps
  • bHLHe17 anticorps
  • HIF-3A anticorps
  • HIF3A anticorps
  • Ipas anticorps
  • Mop7 anticorps
  • NEPAS anticorps
  • PASD7 anticorps

Protein level used designations for HIF3A

HIF3-alpha-1 , PAS domain-containing protein 7 , basic-helix-loop-helix-PAS protein MOP7 , class E basic helix-loop-helix protein 17 , hypoxia-inducible factor 3-alpha , inhibitory PAS domain protein , member of PAS protein 7 , HIF-3-alpha , HIF3-alpha , hypoxia inducible factor three alpha , neonatal and embryonic PAS , HIF-3 alpha , HIF3 alpha 1 , hypoxia inducible factor 3 alpha , hypoxia inducible factor 3a , hypoxia-inducible factor 3 alpha , hypoxia inducible factor 3, alpha subunit , hypoxia-inducible factor-3 alpha , hypoxia-inducible factor 3-alpha-like

GENE ID SPECIES
64344 Homo sapiens
53417 Mus musculus
64345 Rattus norvegicus
456149 Pan troglodytes
476429 Canis lupus familiaris
507699 Bos taurus
100135687 Ovis aries
100413902 Callithrix jacchus
100442498 Pongo abelii
100473029 Ailuropoda melanoleuca
100582446 Nomascus leucogenys
100621574 Sus scrofa
100071095 Equus caballus
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