Immature Colon Carcinoma Transcript 1 Protéines (ICT1)

The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. De plus, nous expédions ICT1 Anticorps (64) et ICT1 Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ICT1 3396 Q14197
ICT1 68572 Q8R035
Rat ICT1 ICT1 303673  
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Top ICT1 Protéines sur anticorps-enligne.fr

Showing 8 out of 10 products:

Catalogue No. Origin Source Conjugué Images Quantité Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Détails
Escherichia coli (E. coli) Humain His-SUMO Tag 100 μg 11 Days
$356.40
Détails
Wheat germ Humain GST tag 10 μg 11 to 12 Days
$414.29
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Détails
Levure Boeuf (Vache) His tag   1 mg 60 to 71 Days
$2,414.50
Détails
Levure REACT_Panda His tag   1 mg 60 to 71 Days
$2,414.50
Détails
Levure REACT_Atlantic Salmon His tag   1 mg 60 to 71 Days
$2,352.17
Détails

ICT1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, , ,
Mouse (Murine)

Plus protéines pour Immature Colon Carcinoma Transcript 1 (ICT1) partenaires d'interaction

Human Immature Colon Carcinoma Transcript 1 (ICT1) interaction partners

  1. miR-1301-3p inhibits cell proliferation via inducing cell cycle arrest and apoptosis through targeting ICT1, and might be a therapeutic target for BC.

  2. High ICT1 expression is associated with leukemia.

  3. ICT1 overexpression notably predicted poor prognosis of gastric cancer patients.

  4. Study demonstrates that ICT1 overexpression correlates with malignant clinical features and poor prognosis of hepatocellular carcinoma (HCC) patients. Functionally, ICT1 promotes proliferation, cell cycle progression and inhibits apoptosis of HCC cells. ICT1 regulates the expressions of CDK1, cyclin B1, Bcl-2 and Bax, and is directly targeted by microRNA-134 (miR-134) in HCC cells.

  5. ICT1 may play a crucial role in promoting gastric cancer proliferation in vitro.

  6. The results provide direct evidence that localized feedbacks on Fat4-Ds1 complexes can give rise to planar cell polarity.

  7. our preliminary study reveals the important role of ICT1 in NSCLC cells that knockdown of ICT1 significantly suppressed cell proliferation, arrested cell cycle though altering expression cell cycle regulators, and promoted cell apoptosis.

  8. ICT1 knockdown significantly inhibited cell proliferation and migration, led to G2/M phase cell-cycle arrest, and triggered apoptosis via the intracellular AMPKa, SAPK/JNK, and PARP signaling pathways.

  9. ICT1 was significantly upregulated in diffuse large B-cell lymphoma tissues (DLBCL) and correlated with poor survival. Knockdown of ICT1 remarkably induced cell cycle G0/G phase arrest and apoptosis in DLBCL cells.

  10. ICT1 knockdown altered the expression of apoptosis- or cell cyclerelated proteins such as Bcl-2, caspase-3, CDK1, CDK2 and cyclin B.

  11. ICT1 may be essential for hydrolysis of prematurely terminated peptidyl-tRNA moieties in stalled mitoribosomes.

Mouse (Murine) Immature Colon Carcinoma Transcript 1 (ICT1) interaction partners

  1. Because ICT1 is essential in human cells, these results suggest that ribosome rescue activity in mitochondria is required in humans

  2. solution structure of the catalytic domain of the ICT1 protein that lacks an N-terminal mitochondrial targeting signal and an unstructured C-terminal basic-residue-rich extension

Profil protéine ICT1

Profil protéine

The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.

Gene names and symbols associated with ICT1

  • mitochondrial ribosomal protein L58 (MRPL58)
  • imitochondrial ribosomal protein L58 S homeolog (mrpl58.S)
  • Immature colon carcinoma transcript 1 (PVX_091510)
  • mitochondrial ribosomal protein L58 (mrpl58)
  • mitochondrial ribosomal protein L58 (Mrpl58)
  • mitochondrial ribosomal protein L58 (ict1)
  • 1110001A02Rik Protéine
  • 1110002E03Rik Protéine
  • DS-1 Protéine
  • DS1 Protéine
  • ICT1 Protéine

Protein level used designations for ICT1

immature colon carcinoma transcript 1 , Immature colon carcinoma transcript 1 , Immature colon carcinoma transcript 1 protein homolog , Peptidyl-tRNA hydrolase ICT1, mitochondrial , digestion substraction 1 , immature colon carcinoma transcript 1 protein , peptidyl-tRNA hydrolase ICT1, mitochondrial , immature colon carcinoma transcript 1 protein homolog

GENE ID SPECIES
422114 Gallus gallus
700207 Macaca mulatta
734168 Xenopus laevis
736364 Pan troglodytes
5474589 Plasmodium vivax Sal-1
100170604 Xenopus (Silurana) tropicalis
100344624 Oryctolagus cuniculus
100466987 Ailuropoda melanoleuca
3396 Homo sapiens
68572 Mus musculus
303673 Rattus norvegicus
515465 Bos taurus
100196025 Salmo salar
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