anti-Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) Anticorps

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals.

afficher tous les anticorps Gène GeneID UniProt
Anti-Souris INPP5B INPP5B 16330 Q8K337
Anti-Rat INPP5B INPP5B 362590  
Anti-Humain INPP5B INPP5B 3633 P32019
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Top anti-INPP5B Anticorps sur anticorps-enligne.fr

Showing 10 out of 44 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-INPP5B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Hela cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB INPP5B Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the INPP5B antibody detected the INPP5B protein (arrow). INPP5B antibody (C-term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the INPP5B antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué EIA, FACS, IHC (p), WB Flow cytometric analysis of CEM cells using INPP5B / 5PTase 2 Antibody (C-term) Cat.-No AP52214PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle reacted with INPP5B / 5PTase 2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Chien Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IHC (p), IHC, WB Western Blot: INPP5B Antibody [NBP1-31705] - Sample (30 ug of whole cell lysate) A: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: INPP5B Antibody [NBP1-31705] - Paraffin-embedded Ca922 xenograft, using antibody at 1:100 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Lapin Inconjugué WB Western Blot: INPP5B Antibody [NBP1-54719] - Hela cell lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: INPP5B Antibody [NBP1-89439] Staining of human cell line U-251MG shows positivity in cytoplasm & cytoskeleton (microtubules). Immunohistochemistry-Paraffin: INPP5B Antibody [NBP1-89439] - Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB   100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using INPP5B, antibody at 1:100 dilution. WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Lapin Inconjugué WB INPP5B antibody used at 1 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 2 to 3 Days
$473.93
Détails

anti-INPP5B Anticorps mieux référencés

  1. Dog (Canine) Polyclonal INPP5B Primary Antibody pour WB - ABIN2785875 : Tothova, Kollipara, Huntly, Lee, Castrillon, Cullen, McDowell, Lazo-Kallanian, Williams, Sears, Armstrong, Passegué, DePinho, Gilliland: FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. dans Cell 2007 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre INPP5B partenaires d’interaction

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) interaction partners

  1. These results suggest that the functions of OCRL (Montrer OCRL Anticorps)/INPP5B and proton-chloride exchange transporter 5 converge on shared mechanisms, the impairment of which has a dramatic effect on proximal tubule endocytosis

  2. study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl (Montrer OCRL Anticorps) function

  3. ADAM cleavage was only modestly impaired in numerous Inpp5b-null males and varied between individual animals.

  4. These results indicate a functional overlap of Ocrl (Montrer OCRL Anticorps) and Inpp5b in most cell lineages, especially in extraembryonic tissues.

  5. Inpp5b role in the regulation of cell adhesion in the testis and in the formation of junctional complexes with neighboring cells

  6. 72-5ptase expression promoted GLUT4 (Montrer SLC2A4 Anticorps) trafficking via a Rab11 (Montrer RAB11A Anticorps)-dependent pathway but not by Rab5 (Montrer RAB5A Anticorps)-mediated endocytosis. Therefore, endogenous PtdIns(3)P at the plasma membrane promotes GLUT4 (Montrer SLC2A4 Anticorps) translocation.

Human Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) interaction partners

  1. OCRL (Montrer OCRL Anticorps)-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells

  2. The crystal structures of human INPP5B in complex with phosphoinositide substrate analogs revealed a membrane interaction patch likely to assist in sequestering substrates from the lipid bilayer.

  3. study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl (Montrer OCRL Anticorps) function

  4. The homologous phosphatase Inpp5b was unable to complement the Ocrl1 (Montrer OCRL Anticorps)-dependent cell migration defect.

  5. INPP5B is also localised to the early secretory pathway including the Golgi apparatus and ER-to-Golgi intermediate compartment (ERGIC).

  6. The NH2-terminal region of OCRL (Montrer OCRL Anticorps), but not of INPP5B, binds clathrin heavy chain (Montrer CLTC Anticorps).

INPP5B profil antigène

Profil protéine

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with INPP5B

  • inositol polyphosphate-5-phosphatase B (INPP5B) anticorps
  • type II inositol 1,4,5-trisphosphate 5-phosphatase-like (LOC100224437) anticorps
  • inositol polyphosphate-5-phosphatase B L homeolog (inpp5b.L) anticorps
  • inositol polyphosphate 5-phosphatase OCRL-1 (LOC100159919) anticorps
  • inositol polyphosphate-5-phosphatase B (Inpp5b) anticorps
  • 5PTase anticorps
  • 75kDa anticorps
  • AW260155 anticorps
  • INPP5P anticorps

Protein level used designations for INPP5B

inositol polyphosphate-5-phosphatase, 75kDa , inositol polyphosphate-5-phosphatase, 75kDa-like , type II inositol-1,4,5-trisphosphate 5-phosphatase-like , 5PTase , inositol polyphosphate-5-phosphatase, 75 kDa , phosphoinositide 5-phosphatase , type II inositol 1,4,5-trisphosphate 5-phosphatase , type II inositol-1,4,5-trisphosphate 5-phosphatase , 75 kDa inositol polyphosphate-5-phosphatase

GENE ID SPECIES
419609 Gallus gallus
456767 Pan troglodytes
538291 Bos taurus
716851 Macaca mulatta
100054559 Equus caballus
100224437 Taeniopygia guttata
100350043 Oryctolagus cuniculus
100381066 Xenopus laevis
100159919 Acyrthosiphon pisum
100512110 Sus scrofa
16330 Mus musculus
362590 Rattus norvegicus
3633 Homo sapiens
100686373 Canis lupus familiaris
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