anti-Interferon-Induced Transmembrane Protein 1 (IFITM1) Anticorps

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. De plus, nous expédions IFITM1 Protéines (7) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
IFITM1 293618  
IFITM1 8519 P13164
IFITM1 68713 Q9D103
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Top anti-IFITM1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 108 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (fro), IHC (p), WB Anti-IFITM1 antibody, Western blotting Lane 1: SW620 Cell Lysate Lane 2: CEM Cell Lysate Anti-IFITM1 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, antibody was diluted at 1:100. 100 μL Connectez-vous pour afficher Disponible
$363.46
Détails
Humain Lapin Inconjugué WB Western blot analysis of CD225 expression in K562 (A), PC12 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A549 B: HeLa 15% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using IFITM1, antibody at 1:500 dilution. 100 μL Connectez-vous pour afficher 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué EIA, IF, WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$522.50
Détails
Humain Lapin Inconjugué IHC (fro), IHC (p), WB IFITM1 Polyclonal Antibody 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$456.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IHC, IHC (p), WB Human Uterus, Myometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of IFITM1 expression in K562,The lane on the left is treated with the antigen-specific peptide. ABIN6273643 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 4 to 8 Days
$522.50
Détails

anti-IFITM1 Anticorps mieux référencés

  1. Human Polyclonal IFITM1 Primary Antibody pour WB - ABIN1881445 : Yang, Chen, Lin, Yu, Liu, Wang, Liu, Chen et al.: Nickel catalysts bearing bidentate alpha-aminoaldimines for ethylene polymerization--independent and cooperative structure/reactivity relationship resulting from unsymmetric square planar... dans Dalton transactions (Cambridge, England : 2003) 2009 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal IFITM1 Primary Antibody pour IHC (fro), IHC (p) - ABIN3044336 : Yang, Xu, Chen, Hu: IFITM1 plays an essential role in the antiproliferative action of interferon-gamma. dans Oncogene 2007 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal IFITM1 Primary Antibody pour ICC, IF - ABIN4321079 : Klymiuk, Kenner, Adler, Busch, Boersma, Irmler, Fridrich, Gailus-Durner, Fuchs, Leitner, Müller, Kühn, Schlederer, Treise, de Angelis, Beckers: In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis. dans PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  4. Polyclonal IFITM1 Primary Antibody pour IHC (fro), IHC (p) - ABIN540567 : Tanaka, Yamaguchi, Tsoi, Lickert, Tam: IFITM/Mil/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion. dans Developmental cell 2005 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal IFITM1 Primary Antibody pour IHC, WB - ABIN5664696 : Teng, Luo, Yu, Chen, Huang, Chen, Xie, Zeng, Luo, Xiong, Liu, Hou, Feng: CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells. dans Genes and immunity 2018 (PubMed)

Plus d’anticorps contre IFITM1 partenaires d’interaction

Human Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. overexpression of IFITM1, 2 and 3 suppressed entry of CXCR4 and CCR5 tropic viruses; entry of transmitted founder HIV-1 in U87 cells is more sensitive to inhibition by IFITM2 and IFITM3 than by IFITM1

  2. High IFITM1 expression is associated with lymph node metastasis and invasion in Gallbladder Adenocarcinomas

  3. Strong ifitm1 Expression in CD4 T Cells in HIV Controllers Is Correlated With Immune Activation

  4. Using a multi-group heat map from GSE9716 analysis of the GEO database, IFITM1 was determined to be a relevant radioresistance gene. Inhibition of IFITM1 in combination with radiotherapy could, indeed, inhibit oral neoplasm cells.

  5. Inactivated viral particle inoculation increased the expression of IFITM1protein at mRNA and protein levels, and mediated the antiviral state in HUVECs.

  6. Identification of three distinct mutations that converted IFITM1 or IFITM3 from inhibitors to enhancers of MERS-CoV or SARS-CoV spike protein-mediated entry revealed key structural motifs or residues determining the biological activities of IFITM proteins.

  7. Epithelial-mesenchymal transition (EMT) signature was dysregulated by both loss and gain of function of IFITM1, which was partially reverted by Caveolin-1 (CAV1).

  8. These results indicate that IFITM1 protein can restrict alphavirus infection by inhibiting viral fusion with cellular membranes.

  9. The transcriptional regulation of IFITM1, 2 and 3 expression.

  10. IFITM1 and IFITM3 inhibit Zika virus infection early in the viral life cycle.

  11. IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT1-mediated induction of p21.

  12. Compared with CD10, IFITM1 has superior performance distinguishing endometrial stroma of adenomyosis from mesenchyma surrounding invasive endometrial adenocarcinoma.

  13. Overexpression of IFITM1 is associated with Oral Squamous Cell Carcinomas.

  14. High expression of IFITM1 is associated with poor prognosis of colorectal cancer.

  15. These findings indicate that overexpression of IFITM1 enhances the aggressive phenotype of triple-negative SUM149 IBC cells and that this effect is dependent on STAT2/BRG1 interaction.

  16. propose that the IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation and demonstrate that the actions of the IFITM proteins are indeed virus and cell-type specific

  17. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  18. Suggest that IFITM1 promotes the aggressiveness of colorectal cancer cells via caveolin-1 signaling.

  19. In virus-producing cells, IFITMs coalesce with forming virions and are incorporated into HIV-1 viral particles.

  20. Incorporation of IFITM1, IFITM2 and IFITM3 into HIV-1 virions impair viral fusion and spread.

Mouse (Murine) Interferon-Induced Transmembrane Protein 1 (IFITM1) interaction partners

  1. Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins.

  2. the importance of the C-terminal region of IFITM1 in modulating the antiviral function through controlling protein subcellular localization.

  3. Palmitoylation of IFITM1 regulates protein stability by preventing proteasomal degradation, and modification of the nonconserved cysteine at the IFITM1 C terminus supports an intramembrane topology with implications for anti-influenza A virus activity.

  4. the fact that IFITM1 can function as a negative regulator of cell proliferation, and because the gene maps to chromosome band 11p15.5, previously associated with NSCLC, it is likely that IFITM1 in man has a key role in tumor formation

  5. Fragilis2 regulates epithelialization of the somites and paraxial mesoderm formation.

  6. The antiproliferative action of IFN-gamma requires the induction of IFITM1.

IFITM1 profil antigène

Profil protéine

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53- dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Gene names and symbols associated with IFITM1

  • interferon induced transmembrane protein 1 (Ifitm1) anticorps
  • interferon induced transmembrane protein 1 (IFITM1) anticorps
  • interferon induced transmembrane protein 1 (9-27) (IFITM1) anticorps
  • 9-27 anticorps
  • 1110036C17Rik anticorps
  • CD225 anticorps
  • DSPA2a anticorps
  • IFI17 anticorps
  • LEU13 anticorps
  • Mil-2 anticorps
  • Mil2 anticorps

Protein level used designations for IFITM1

interferon-induced transmembrane protein 1 , interferon induced transmembrane protein 1 (9-27) , interferon induced transmembrane protein 1 , dispanin subfamily A member 2a , interferon-induced protein 17 , interferon-inducible protein 9-27 , leu-13 antigen , fragilis protein 2 , fragilis2 , ifitm-like protein 2 , interferon induced transmembrane protein 2 like , interferon-induced membrane protein Leu-13/9-27 , interferon-induced transmembrane protein 1 (9-27) , interferon-induced transmembrane protein 1 (9-27) isoform 1

GENE ID SPECIES
293618 Rattus norvegicus
100455800 Pongo abelii
100526663 Pan troglodytes
8519 Homo sapiens
68713 Mus musculus
697687 Macaca mulatta
353510 Bos taurus
Fournisseurs de qualité sélectionnés pour anti-IFITM1 (IFITM1) Anticorps
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