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Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. De plus, nous expédions Interleukin 1 Family Member 9 Anticorps (81) et Interleukin 1 Family Member 9 Protéines (42) et beaucoup plus de produits pour cette protéine.
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Human IL1F9 Kit ELISA pour Sandwich ELISA - ABIN572390
Takahashi, Nishida, Shioya, Imaeda, Bamba, Inatomi, Shimizu, Kitoh, Andoh: Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts. dans PLoS ONE 2015
Cathepsin S (Montrer CTSS Kits ELISA) was identified as the major IL-36gamma-activating protease expressed in epithelial cells.
IL-36-mediated IL-6 (Montrer IL6 Kits ELISA) and CXCL8 (Montrer IL8 Kits ELISA) production in human lung fibroblasts and bronchial epithelial cells may be involved in pulmonary inflammation especially caused by bacterial or viral infections.
IL-36gamma inhibits differentiation and induces inflammation of keratinocyte via Wnt (Montrer WNT2 Kits ELISA) signaling pathway in psoriasis.
IL-36gamma-stimulated endothelial cells secrete the proinflammatory chemokines IL-8 (Montrer IL8 Kits ELISA), CCL2 (Montrer CCL2 Kits ELISA) and CCL20 (Montrer CCL20 Kits ELISA).
skin injury increases IL-36gamma via the activation of TLR3 (Montrer TLR3 Kits ELISA)-SLUG-VDR (Montrer CYP27B1 Kits ELISA) axis and IL-36gamma induces REG3A (Montrer REG3A Kits ELISA) to promote wound healing
Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2 (Montrer GABPA Kits ELISA)-IL-36gamma Pathway
IL-36gamma, a member of the IL-1 (Montrer IL1A Kits ELISA) superfamily, is involved in host defense and contributes to proinflammatory responses and development of inflammatory diseases.
Study shows that plasma concentrations of IL-36alpha and IL-36gamma are overexpressed in active systemic lupus erythematosus patients and that IL-36alpha has a substantial pro-inflammatory effect through regulation of IL-6 (Montrer IL6 Kits ELISA) and CXCL8 (Montrer IL8 Kits ELISA) production.
IRF6 is likely to promote inflammation to P. gingivalis through its regulation of IL-36gamma.
Findings indicate that Interleukin (IL)-1beta (Montrer IL1B Kits ELISA)-induced interleukin 36 gamma (IL-36gamma) expression is mediated by the activation of transcriptional factors, NF-kappaB (Montrer NFKB1 Kits ELISA) p65 and AP-1 (c-jun (Montrer JUN Kits ELISA)).
results uncover an important role for IkappaBzeta (Montrer NFKBIZ Kits ELISA) in IL-36 signaling and validate IkappaBzeta (Montrer NFKBIZ Kits ELISA) as an attractive target for psoriasis therapy.
This study defines a critical IL-36/IL-23 (Montrer IL23A Kits ELISA)/IL-22 (Montrer IL22 Kits ELISA) cytokine network instrumental for antimicrobial peptide (Montrer CAMP Kits ELISA) production and host defense in intestinal mucosa damage using a mouse inflammatory bowel disease model.
these findings reveal a fundamental contribution for the IL-36/IL-36R axis in regulating the Treg-Th9 cell balance with broad implications for Th cell-mediated disorders, such as inflammatory bowel diseases and particularly ulcerative colitis
Data presented herein shed further light on involvement of T-bet in innate immunity and suggest that IL-36gamma, besides IFNgamma, may contribute to functions of this transcription factor in immunopathology.
Interleukin-36 (Montrer IL1F6 Kits ELISA) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
A critical role of IL-36R (Montrer IL1RL2 Kits ELISA) ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.
Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
, IL-1 related protein 2
, IL-1-related protein 2
, interleukin 1 family, member 9
, interleukin 1-related protein 2
, interleukin-1 epsilon
, interleukin-1 family member 9
, interleukin-1 homolog 1
, interleukin-36 gamma