Interleukin 1 Receptor-Like 1 Protéines (IL1RL1)

The protein encoded by IL1RL1 is a member of the interleukin 1 receptor family. De plus, nous expédions IL1RL1 Anticorps (127) et IL1RL1 Kits (31) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
IL1RL1 17082 P14719
IL1RL1 9173 Q01638
Rat IL1RL1 IL1RL1 25556 Q62611
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Showing 10 out of 23 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
HEK-293 Cells Humain Inconjugué   25 μg Connectez-vous pour afficher 10 to 12 Days
HOST_Human Cells Humain Fc Tag 100 μg Connectez-vous pour afficher 20 to 21 Days
HEK-293 Cells Humain Fc Tag Human IL-1RL1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. Immobilized Human IL-33, Tag Free  with a linear range of 1.95-7.8 ng/mL. 200 μg Connectez-vous pour afficher 21 to 31 Days
HOST_Human Cells Souris Fc Tag 100 μg Connectez-vous pour afficher 20 to 21 Days
HOST_Human Cells Humain Inconjugué 100 μg Connectez-vous pour afficher 20 to 21 Days
CHO Cells Humain DYKDDDDK Tag Validation with Western Blot 50 μg Connectez-vous pour afficher 6 to 10 Days

IL1RL1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) , , ,
, ,
Human , , , , ,
, , , ,

Plus protéines pour Interleukin 1 Receptor-Like 1 (IL1RL1) partenaires d'interaction

Mouse (Murine) Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. an increased prevalence in neonatal mortality was observed in litters from dams lacking ST2

  2. Taken together, the data demonstrate a critical role of MyD88 (Montrer MYD88 Protéines) in DCs and of IL-33 (Montrer IL33 Protéines) signaling via ST2 (Montrer SULT2A1 Protéines) in MC903-induced Atopic dermatitis (AD). These data suggest that IL-33 (Montrer IL33 Protéines)/IL-33R may be a therapeutic target of AD.

  3. Heligmosomoides polygyrus Alarmin Release Inhibitor (HpARI) prevents binding of active interleukin-33 (IL-33 (Montrer IL33 Protéines)) to the IL-33 (Montrer IL33 Protéines) receptor.

  4. this study shows that ST2 (Montrer SULT2A1 Protéines) regulates early IL-13 (Montrer IL13 Protéines) production in fungus-induced allergic airway inflammation

  5. mice deficient in the receptor for IL-33 (Montrer IL33 Protéines) (Il1rl1-/-) demonstrated enhanced lung clearance of Aspergillus fumigatus

  6. This stuidy shown that the mRNA expression of IL-33 and ST2 receptors is increased in the CNS of Rocio virus-infected WT mice and that ST2(-/-) mice showed increased susceptibility to infection.

  7. Liver Treg cells show a high expression of ST2 (Montrer SULT2A1 Protéines), a cellular receptor for tissue alarmin IL-33 (Montrer IL33 Protéines), which is strongly upregulated in the liver of infected mice. These results illustrate the importance of IL-33 (Montrer IL33 Protéines) in the suppressive function of liver Treg cells during Cytomegaloviruses (CMVs) infection.

  8. these studies establish a basal defect in eosinophilopoiesis in IL-33 (Montrer IL33 Protéines)- and ST2 (Montrer SULT2A1 Protéines)-deficient mice and a mechanism whereby IL-33 (Montrer IL33 Protéines) supports eosinophils by driving both systemic IL-5 (Montrer IL5 Protéines) production and the expansion of IL-5Ralpha-expressing precursor cells

  9. These results shed light on endogenous IL-33/ST2 signaling as a potential immune regulatory mechanism that serves to promote beneficial microglial responses and mitigate ischemic brain injury after stroke.

  10. Plasmodium berghei infection triggered a dramatic increase of IL-33 expression by oligodendrocytes, through ST2 pathway.

Human Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. present study highlights significant associations between ST2 and inflammatory bowel disease.

  2. Data show that interleukin-2 receptor alpha (Montrer IL2RA Protéines), tumor necrosis factor receptor 1 (Montrer TNFRSF1A Protéines), serum STimulation-2 (IL1RL1 gene product), and regenerating islet-derived 3-alpha (Montrer REG3A Protéines) were significantly associated with non-relapse mortality.

  3. Serum IL-33 (Montrer IL33 Protéines) and sST2 (Montrer SSTR2 Protéines) levels, and CD4 (Montrer CD4 Protéines)+ST2L+ expression in peripheral blood mononuclear cells are closely associated with HIV-1 infection and immune reconstitution in patients received highly-active antiretroviral therapy.

  4. Elevated levels of sST2 (Montrer SSTR2 Protéines) concentration in stable coronary heart disease patients may independently predict short- and long-term risk for fatal CVD events and total mortality but not non-fatal CVD events.

  5. Patients with severe aortic valve stenosis present elevated sST2 (Montrer SSTR2 Protéines) levels. Left ventricular global longitudinal strain resulted the only independent predictor of sST2 (Montrer SSTR2 Protéines) levels.

  6. The Il1RL1 rs950880 AA homozygote is an independent predictor of all-cause mortality in coronary artery disease and peripheral arterial disease patients.

  7. In a cohort of hypertensive heart failure subjects, soluble ST2 correlates significantly with indicators of right ventricular function.

  8. Data provide evidence that increased IL-33/ST2 levels in patients with chronic kidney disease are an indicator of increased inflammation, impaired endothelial functions, and cardiovascular events.

  9. Serum levels of IL33R were positively correlated with cognitive performance in patients with schizophrenia.

  10. Interleukin 1 receptor-like 1 (ST2/IL1RL1) is a biomarker for cardiac stress and heart failure, which can be associated with cocaine use. Data suggest that serum ST2/IL1RL1 levels are up-regulated by cocaine use; cocaine use appears to be associated with subclinical cardiac stress and damage outside of acute cardiac events; elevated serum ST2/IL1RL1 levels may serve as biomarkers for cocaine-induced cardiac complications.

Profil protéine IL1RL1

Profil protéine

The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with IL1RL1

  • interleukin 1 receptor-like 1 (Il1rl1)
  • interleukin 1 receptor like 1 (IL1RL1)
  • DER4 Protéine
  • FIT-1 Protéine
  • FIT1 Protéine
  • IL33R Protéine
  • Ly84 Protéine
  • ST2 Protéine
  • St2-rs1 Protéine
  • ST2L Protéine
  • ST2V Protéine
  • T1 Protéine
  • T1/ST2 Protéine

Protein level used designations for IL1RL1

T1 , interleukin-1 receptor-like 1 , lymphocyte antigen 84 , protein T1 , growth stimulation-expressed , homolog of mouse growth stimulation-expressed , interleukin 1 receptor-related protein , fos-responsive gene 1 protein

17082 Mus musculus
9173 Homo sapiens
611442 Canis lupus familiaris
374136 Gallus gallus
25556 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour IL1RL1 Protéines (IL1RL1)
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