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The protein encoded by IL22RA1 belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22).
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Mouse (Murine) Monoclonal IL22 Receptor alpha 1 Primary Antibody pour CyTOF, FACS - ABIN4899326
Li, Burns, Miller, Smith: CCL20, γδ T cells, and IL-22 in corneal epithelial healing. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
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Human Monoclonal IL22 Receptor alpha 1 Primary Antibody pour CyTOF, FACS - ABIN4899325
Perriard, Mathias, Enz, Canales, Schluep, Gentner, Schaeren-Wiemers, Du Pasquier: Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. dans Journal of neuroinflammation 2015
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Human Monoclonal IL22 Receptor alpha 1 Primary Antibody pour FACS - ABIN4895922
Maarof, Bouchet-Delbos, Gary-Gouy, Durand-Gasselin, Krzysiek, Dalloul: Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells. dans Blood 2010
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Human Polyclonal IL22 Receptor alpha 1 Primary Antibody pour IF (p), IHC (p) - ABIN748178
Guo, Wu, Cen, Li, Kong, Zhou: IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis. dans Virology journal 2014
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Human Monoclonal IL22 Receptor alpha 1 Primary Antibody pour FACS - ABIN4895924
Tohyama, Hanakawa, Shirakata, Dai, Yang, Hirakawa, Tokumaru, Okazaki, Sayama, Hashimoto: IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. dans European journal of immunology 2009
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increased expression of IL-22Ralpha therefore promotes keratinocyte proliferation and pro-inflammatory cytokine production during UVB-induced skin inflammation, suggesting that UVB facilitates skin inflammation by increasing the responsiveness of keratinocytes to IL-22 (Montrer IL22 Anticorps)
IL-22 (Montrer IL22 Anticorps) and its receptor have a crucial role in the development and pathogenesis of uveitis by facilitating inflammatory cell infiltration.
phosphorylation of STAT3 (Montrer STAT3 Anticorps) and AKT (Montrer AKT1 Anticorps) was highly induced by treatment with IL-22 (Montrer IL22 Anticorps) via IL-22R1. IL-22R1 was also consistently overexpressed in recurrent NSCLC tissues
These data suggest that imbalance of IL-22 (Montrer IL22 Anticorps)/IL-22R1 signaling regulates the pathogenesis of chronic rhinosinusitis with nasal polyps, including local eosinophilia, via alteration of MUC1 (Montrer MUC1 Anticorps) expression.
FBXW12 (Montrer FBXW12 Anticorps) functions as an E3 ligase constituent to ubiquitinate and degrade IL-22R and that therapeutic FBXW12 (Montrer FBXW12 Anticorps) inhibition may enhance IL-22 (Montrer IL22 Anticorps) signaling and bolster mucosal host defense and infection containment.
IL-22R1 is over-expressed in primary Sjogren's syndrome and Sjogren-associated non-Hodgkin lymphomas and is regulated by IL-18 (Montrer IL18 Anticorps).
IL-22 (Montrer IL22 Anticorps) has restricted tissue specificity as its unique receptor IL-22R1 is exclusively expressed on epithelial and tissue cells, but not immune cells.
serum IL-22 (Montrer IL22 Anticorps) levels are significantly higher in patients with pituitary macroadenomas than in healthy controls and IL-22R is variably expressed in both prolactinoma and non-functioing pituitary adenoma cells.
High expression of interleukin-22 (Montrer IL22 Anticorps) receptor is associated with pancreatic ductal adenocarcinoma.
Letter: calcipotriol inhibits the IL-22 (Montrer IL22 Anticorps)-induced epidermal hyperplasia by decreasing keratinocyte proliferation and down-modulating IL-22R expression.
Endogenous IL-22 (Montrer IL22 Anticorps) and hepatic IL-22R signaling play critical roles in controlling pneumococcal lung burden, and systemic IL-22 (Montrer IL22 Anticorps) decreases bacterial burden in the lungs and peripheral organs by potentiating C3 opsonization on bacterial surfaces, through the increase of hepatic C3 expression.
our data suggest that IL-20 (Montrer IL20 Anticorps) subfamily cytokines, particularly IL-20 (Montrer IL20 Anticorps), IL-22 (Montrer IL22 Anticorps), and IL-24 (Montrer IL24 Anticorps), might provide therapeutic benefit for patients with Diabetic foot ulcers (DFU) .
this study shows that IL-22 (Montrer IL22 Anticorps) plays role in acute graft versus host disease via IL-22R-STAT3 (Montrer STAT3 Anticorps) pathway
RNA sequencing analyses of primary colonic organoids showed that IL-22RA1 signaling promotes intestinal fucosylation via induction of the fucosyltransferase Fut2 (Montrer FUT2 Anticorps).
These findings reveal the ability of GSK-3beta to modulate IL-22R protein stability that might have significant implications for cytoprotective functions and therapeutic targeting of the IL-22 (Montrer IL22 Anticorps) signaling axis.
IL-22R was up-regulated in lymphoid organs and joints during the course of arthritis.
This study documents a previously unknown role of IL-22R1 in inflammation and identifies the involvement of IL-22R1/IL-22 (Montrer IL22 Anticorps) in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
Genomic structure and inducible expression of the IL-22 (Montrer IL22 Anticorps) receptor alpha chain (Montrer FCGRT Anticorps).
SNPs in IFNG (Montrer IFNG Anticorps), IFNGR1 (Montrer IFNGR1 Anticorps) and R2, IL22 (Montrer IL22 Anticorps), and IL22RA1 were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.
interleukin 22 receptor, alpha 1
, IL-22 receptor subunit alpha-1
, cytokine receptor class-II member 9
, cytokine receptor family 2 member 9
, interleukin-22 receptor subunit alpha-1
, interleukin-22 receptor alpha chain