anti-Interleukin 22 Receptor, alpha 2 (IL22RA2) Anticorps

The protein encoded by IL22RA2 is a soluble class II cytokine receptor. De plus, nous expédions IL22RA2 Kits (19) et IL22RA2 Protéines (12) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
IL22RA2 116379 Q969J5
IL22RA2 237310 Q80XF5
IL22RA2 444986 Q7TNI4
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Top anti-IL22RA2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 73 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Chien Lapin Inconjugué WB WB Suggested Anti-IL22RA2 Antibody Titration: 1.0 ug/ml Positive Control: RPMI-8226 Whole Cell 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of IL-22RA2 expression in HeLa (A), MCF7 (B), mouse heart (C), rat heart (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-IL-22BP Polyclonal Antibody, Unconjugated (ABIN748193) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat lung labeled with Anti-IL-22BP Polyclonal Antibody, Unconjugated (ABIN748193) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL 3 to 7 Days
$317.90
Détails
Souris Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Rat Spleen lysate; Primary Ab: 3µg/ml Rabbit Anti-Mouse IL22Ra2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$360.00
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis IL22RA2 using HepG2 whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image IL22 Receptor alpha 2 antibody detects IL22RA2 protein at cytosol on PC14 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded PC14 xenograft. IL22 Receptor alpha 2 antibody , dilution: 1:250. WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 12% SDS PAGE antibody diluted at 1:200 100 μL 3 to 4 Days
$466.18
Détails
Rat Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Rat Spleen lysate; Primary Ab: 5µg/ml Rabbit Anti-Rat IL22Ra2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$380.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in T47D cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Détails
Souris Lapin Inconjugué IF/ICC, IHC, IP, WB Western blot analysis of Rat Spleen lysate, using Mouse IL22Ra2 Antibody (3 µg/ml) and HRP-conjugated Goat Anti-Rabbit antibody ( Western blot analysis of the recombinant protein. 100 μg 16 to 26 Days
$454.83
Détails
Souris Mouton APC FACS   100 Tests 11 to 14 Days
$1,057.83
Détails

anti-IL22RA2 Anticorps mieux référencés

  1. Human Polyclonal IL22RA2 Primary Antibody pour IHC, IHC (p) - ABIN4324964 : Laaksonen, Guerreiro-Cacais, Adzemovic, Parsa, Zeitelhofer, Jagodic, Olsson: The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation. dans Genes and immunity 2014 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre IL22RA2 partenaires d’interaction

Human Interleukin 22 Receptor, alpha 2 (IL22RA2) interaction partners

  1. IL-22BP expression was downregulated in skin biopsies of psoriasis patients compared to the skin of healthy donors.

  2. expression higher in the epidermal compartment of the skin in comparison with dermis in both healthy skin and psoriasis skin

  3. suggest that the human IL-22BP isoforms have distinct spatial and temporal roles and coordinately fine-tune IL-22-dependent STAT3 responses in tissues as a type of rheostat.

  4. thia study shows shows that nonaffected skin of psoriasis patients displays lower expression of IL-22BP than skin of healthy controls, and that the strong IL-22 increase in lesional psoriatic skin is accompanied by a moderate induction of IL-22BP

  5. The deletion of IFNGR1 causes complete IFN-gammaR1 deficiency. Despite the deletion ending very close to the IL22RA2 gene, it does not appear to affect IL22RA2 transcription.

  6. IL-22BP is produced by eosinophils in the gut and blocks IL-22 protective actions in colitis.

  7. Through a combined approach including genetic and immunological investigation in an animal model and large-scale association studies of patients with multiple sclerosis (MS), IL-22RA2 is established as an MS risk gene.

  8. The IL-22R and IL-10R2 binding sites are juxtaposed on adjacent IL-22 surfaces contributed mostly by helices A, D, and F and loop AB.

  9. Crystallization and preliminary X-ray diffraction results of the IL-22-IL-22 binding protein (IL-22BP) complex are described.

  10. Comparison of IL-22/IL-22BP and IL-22/IL-22R1 crystal structures shows that both receptors display an overlapping IL-22 binding surface, which is consistent with the inhibitory role played by IL-22 binding protein.

  11. Polymorphisms in IL22RA1 are associated with severe CRS.

Mouse (Murine) Interleukin 22 Receptor, alpha 2 (IL22RA2) interaction partners

  1. This study used the TLR7 agonist Imiquimod (IMQ) to induce a psoriasis-like skin disease in mice and found a strong downregulation of IL-22BP in the affected skin as well as in the lymph nodes of animals treated with IMQ.

  2. This study demonstrated that the IL-22/IL-22BP system plays a major role during Pseudomonas aeruginosa pneumonia by moderating neutrophil accumulation in the lungs that ultimately leads to epithelium protection.

  3. limits the pathological manifestations in models of allergic contact dermatitis and psoriasis

  4. Il22bp-deficient mice were more susceptible to acute liver damage in models of acute liver damage induced by ischemia reperfusion and acetaminophen administration. IL-22BP plays a protective role in acute liver damage, via controlling IL-22-induced Cxcl10 expression.

  5. IL-22BP promotes bacterial uptake into Peyer's patches by influencing follicle-associated epithelium gene expression and function.

  6. IL22RA2 KO displayed a less severe EAE course, less demyelination and less infiltration of immune cells in the CNS.

  7. the IL-22-IL-22BP axis critically regulates intestinal tissue repair and tumorigenesis in the colon

  8. cloning and characterization; gene encodes a protein of 230 amino acids that share 67.1% amino-acid sequence identity with human IL-22 binding protein; upregulated by LPS stimulation in monocytes

IL22RA2 profil antigène

Profil protéine

The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene names and symbols associated with IL22RA2

  • interleukin 22 receptor subunit alpha 2 (IL22RA2) anticorps
  • interleukin 22 receptor, alpha 2 (IL22RA2) anticorps
  • interleukin 22 receptor, alpha 2 (Il22ra2) anticorps
  • interleukin 22 receptor subunit alpha 2 (Il22ra2) anticorps
  • CRF2-10 anticorps
  • Crf2-s1 anticorps
  • CRF2X anticorps
  • Il-22bp anticorps
  • IL-22R-alpha-2 anticorps
  • IL-22RA2 anticorps
  • ZCYTOR16 anticorps

Protein level used designations for IL22RA2

interleukin 22-binding protein , interleukin 22 receptor, alpha 2 , interleukin 22-binding protein-like , cytokine receptor class-II member 10 , cytokine receptor family type 2, soluble 1 , interleukin-22 receptor subunit alpha-2 , IL-22 receptor subunit alpha-2 , IL-22R-alpha-2 , IL-22RA2 , IL22BP , cytokine receptor family II soluble 1 , interleukin-22-binding protein , zcytoR16 , IL-22BP

GENE ID SPECIES
472133 Pan troglodytes
533061 Bos taurus
611470 Canis lupus familiaris
770428 Gallus gallus
116379 Homo sapiens
237310 Mus musculus
444986 Rattus norvegicus
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