anti-Interleukin 27 (IL27) Anticorps

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. De plus, nous expédions IL27 Kits (53) et IL27 Protéines (22) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
IL27 246778 Q8NEV9
IL27 365368  
IL27 246779 Q8K3I6
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Top anti-IL27 Anticorps sur

Showing 10 out of 164 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Souris Souris Inconjugué ICS, Neut   0.5 mg Connectez-vous pour afficher 6 to 8 Days
Humain Lapin Inconjugué WB WB Suggested Anti-IL27 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Fetal Lung 100 μL Connectez-vous pour afficher 2 to 3 Days
Humain Souris Inconjugué CyTOF, FACS Detection of IL-27 in PHA + IL-2-treated Human PBMC by Flow Cytometry. Human PBMC, treated with 5 ug/mL PHA and 5 ng/mL rhIL-2 (dark orange filled histogram), or untreated (open histogram, yellow line) were stained with Mouse Anti-Human IL-27 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Connectez-vous pour afficher 8 to 9 Days
Souris Rat Inconjugué WB 25 μL Connectez-vous pour afficher 1 to 2 Days
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
Souris Lapin Inconjugué WB Detection of recombinant IL27/p28 protein by anti-Mouse IL-27/p28 antibody. Recombinant mouse IL27/p28 was loaded on to an SDS-PAGE gel at 0.25 µg and after separation, transferred to nitrocellulose. The membrane was blocked with 1% BSA in TBST for 30 min at RT, followed by incubation with primary antibody diluted 1:1,000 in 1% BSA in TBST overnight at 4°C. After washes, the blot was reacted with secondary antibody HRP Goat anti-Rabbit IgG antibody diluted 1:40,000 in blocking buffer (p/n MB-070) for 30 min at RT. Data was collected using Bio-Rad VersaDoc® 4000 MP imaging system. 100 μg Connectez-vous pour afficher 1 to 2 Days
Humain Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 7 to 9 Days
Souris Lapin Inconjugué WB IL27 Antibody (Center) (ABIN658144) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the IL27 antibody detected the IL27 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
Souris Lapin HRP WB Recombinant mouse IL27/p28 was loaded at 0.25 µg. The blot was blocked with 1% BSA in TBST for 30 min at RT. Blot was incubated with HRP rabbit anti-Mouse IL-27/p28 in 1% BSA/TBST at 1:5,000 for 30 min at RT. Data was collected using Bio-Rad VersaDoc® 4000 MP. 100 μg Connectez-vous pour afficher 1 to 2 Days
Souris Rat Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days

IL27 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-IL27 Anticorps mieux référencés

  1. Mouse (Murine) Monoclonal IL27 Primary Antibody pour ICS, Neut - ABIN2689756 : Hall, Silver, Hunter: The immunobiology of IL-27. dans Advances in immunology 2012 (PubMed)
    Show all 7 Pubmed References

  2. Mouse (Murine) Polyclonal IL27 Primary Antibody pour WB - ABIN1043831 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. dans Immunity 2002 (PubMed)

  3. Mouse (Murine) Monoclonal IL27 Primary Antibody pour WB - ABIN1043835 : Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. dans Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  4. Mouse (Murine) Monoclonal IL27 Primary Antibody pour FACS - ABIN4896017 : Yoshida, Yoshimi, Yoshii, Kim, Dey, Xiong, Munasinghe, Yazawa, ODonovan, Maximova, Sharma, Zhu, Wang, Morse, Ozato: The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation. dans Immunity 2014 (PubMed)

  5. Human Monoclonal IL27 Primary Antibody pour CyTOF, FACS - ABIN4900122 : Seyerl, Kirchberger, Majdic, Seipelt, Jindra, Schrauf, Stöckl: Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. dans European journal of immunology 2010 (PubMed)

Plus d’anticorps contre IL27 partenaires d’interaction

Human Interleukin 27 (IL27) interaction partners

  1. this study found elevated expression of IL-27 in human peripheral serum and elevated expression of its specific receptor (wsx-1 (Montrer IL27RA Anticorps)) on fetal membranes in cases of preterm birth

  2. results indicate that elevated IL-27 strongly correlates with EOS (Montrer IKZF4 Anticorps) and may provide additional diagnostic value along with PCT (Montrer UROD Anticorps).

  3. serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barre syndrome

  4. Expression of IL-27 in the serum was markedly increased in patients with sepsis-induced myo (Montrer IRF6 Anticorps)cardial dysfunction compared with that in controls.

  5. IL-27 significantly inhibited the M2 macrophages polarization and dampened the proliferation, migration and metastasis of pancreatic cancer cells and as well enhanced the efficacy of gemcitabine.

  6. IL-27 increased NLRP3 (Montrer NLRP3 Anticorps) inflammasome activation in monocytes with enhanced release of IL-1 beta (Montrer IL1B Anticorps).

  7. this study shows that interleukin 27 is up-regulated in patients with active inflammatory bowel disease

  8. IL-27 polymorphisms might play a protective role for the development of ulcerative colitis in the Mexican population

  9. Nrf2 (Montrer GABPA Anticorps) Induces IL-17D (Montrer IL17D Anticorps) to mediate tumor and virus surveillance.

  10. IL-27 stimulation activated STAT1 (Montrer STAT1 Anticorps) and STAT3 (Montrer STAT3 Anticorps) in HeLa and T98G cells, suggesting that IL-27 engages the STAT1 (Montrer STAT1 Anticorps)/3 pathway, which then leads to the upregulation of IL-6 (Montrer IL6 Anticorps), IP-10 (Montrer CXCL10 Anticorps), and MIG (Montrer CXCL9 Anticorps)

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. TTP (Montrer ZFP36 Anticorps), encoded by Zfp36 (Montrer ZFP36 Anticorps), degrades p28 (Montrer GSTO1 Anticorps) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  2. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (Montrer TXNRD1 Anticorps)-like cells in celiac disease

  3. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (Montrer TP53 Anticorps) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  4. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (Montrer LTF Anticorps).

  5. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (Montrer TLR4 Anticorps) injection compared with control specimens.

  6. these findings highlight critical roles for IFN-gamma (Montrer IFNG Anticorps) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

  7. IL-27-induced Sca-1 (Montrer Ly6a Anticorps)(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (Montrer EOMES Anticorps) and Blimp1 (Montrer PRDM1 Anticorps).

  8. found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (Montrer IL6 Anticorps) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27

  9. We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.

  10. These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 profil antigène

Profil protéine

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with anti-Interleukin 27 (IL27) Anticorps

  • interleukin 27 (IL27) anticorps
  • interleukin 27 (Il27) anticorps
  • IL-27 anticorps
  • IL-27A anticorps
  • IL-27p28 anticorps
  • IL27 anticorps
  • IL27A anticorps
  • IL27p28 anticorps
  • Il30 anticorps
  • p28 anticorps
  • RGD1561420 anticorps

Protein level used designations for anti-Interleukin 27 (IL27) Anticorps

IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 , interleukin 27 p28 subunit , p28

246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
Fournisseurs de qualité sélectionnés pour anti-IL27 (IL27) Anticorps
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