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IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. De plus, nous expédions Interleukin 31 Anticorps (132) et Interleukin 31 Protéines (43) et beaucoup plus de produits pour cette protéine.
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Mouse (Murine) IL31 Kit ELISA pour Sandwich ELISA - ABIN415707
Yamada, Ueda, Nakamura, Kanayama, Tamura, Hashimoto, Matsumoto, Ishii: Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice. dans Experimental dermatology 2017
Show all 2 Pubmed References
Human IL31 Kit ELISA pour Sandwich ELISA - ABIN417593
Vangerven, Delrue, Brugman, Cosaert: A new therapeutic approach to accidental intra-arterial injection of thiopentone. dans British journal of anaesthesia 1989
Human IL31 Kit ELISA pour Sandwich ELISA - ABIN625326
Zeng, Zhang, Gao, Wang, Yu, Zhou, Xi: Clinical Significance of Serum Interleukin-31 and Interleukin-33 Levels in Patients of Endometrial Cancer: A Case Control Study. dans Disease markers 2016
The findings suggest that rs7977932 and rs4758680 of IL-31 may be associated with the development and progression of the epithelial ovarian cancer in the Chinese population.
this study shows that decreased serum levels of IL-31 correlate in treated patients with Relapsing-Remitting Multiple Sclerosis
review: in-depth overview of the role of IL-31 in chronic skin diseases and the possible diagnostic and therapeutic applications in the management of these diseases
Obtained results, as well as literature data, show that lower concentration of IL-31 in patients' serum may be correlated with its role in JAK (Montrer JAK3 Kits ELISA)/STAT (Montrer STAT1 Kits ELISA) signaling pathway which is involved in development of autoimmune blistering disease
IL-31 gene polymorphisms were tightly associated with dilated cardiomyopathy susceptibility and contributed to worse prognosis in DCM patients.
This study indicated that CXCL13 (Montrer CXCL13 Kits ELISA) rather than IL-31 may have clinical values of diagnosis and prognosis in hepatocellular carcinoma.
The first demonstration of the involvement of the IL-31/IL-31R axis in cancer came from studies in patients with mycosis fungoides/Sezary syndrome, the most frequent, cutaneous T cell lymphoma. Tumor cells were shown to produce IL-31, whose serum levels correlated with pruritus intensity.
IL31 and its receptor, IL31RA (Montrer IL31RA Kits ELISA), are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.
this study shows that IL-31 may be involved in the pathogenesis of asthma and rhinitis; dust mite and mugwort allergy could increase it significantly
While serum TSLP (Montrer TSLP Kits ELISA) levels were unaffected by concomitant allergies and atopic comorbidities, serum levels of IL-31, IL-33 (Montrer IL33 Kits ELISA) and sST2 (Montrer SSTR2 Kits ELISA) were affected to a small extent. We found a positive correlation between TSLP (Montrer TSLP Kits ELISA), IL-31 and IL-33 (Montrer IL33 Kits ELISA), and an inverse relationship between IL-33 (Montrer IL33 Kits ELISA) and sST2 (Montrer SSTR2 Kits ELISA)
IL-31 increased the concentration of intracellular Ca(2 (Montrer CA2 Kits ELISA)+) ions in mouse keratinocytes.
IL-31 elicits itch not only through direct action on primary sensory neurones, but also by inducing LTB4 (Montrer PTGR1 Kits ELISA) production in keratinocytes.
Oncostatin M (Montrer OSM Kits ELISA) and interleukin-31: Cytokines, receptors, signal transduction and physiology.
IL-31 upregulates IL-31RA (Montrer IL31RA Kits ELISA) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (Montrer IL31RA Kits ELISA) expression in mice
our results suggest a functional cooperation between NFAT1 (Montrer NFAT1 Kits ELISA) and JunB (Montrer JUNB Kits ELISA) in mediating IL-31 gene expression in CD4 (Montrer CD4 Kits ELISA)(+) T cells
Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.
IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases
IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.
these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004
, interleukin 31